Drugs by active ingredient: adverse event reports that FDA received

367 single ingredients and combinations, A to Z

A drug on this list is a set of active ingredients: one ingredient, or a combination. A brand name is not on this list. Brand names A to Z gives the active ingredients of each brand name.

Search engines list 153 of these pages. Each has 500 reports or more in all years and 30 reports or more in the latest 12 months. The other pages stay on the site and are in the table.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

The list

Sets of active ingredients with 50 or more reports, in order of name
Active ingredients	Species in the largest number of reports	Reports, all years	Reports, latest 12 months	Approved applications in the Green Book	Listed by search engines
(S) - methoprene	Dog	6,186	178	1	Yes
Acepromazine Maleate	Dog	2,597	140	8	Yes
Acetaminophen	Dog	87	24	None	No
Acetylsalicylic Acid	Dog	177	4	None	No
Afoxolaner	Dog	61,428	2,823	1	Yes
Afoxolaner + Moxidectin + Pyrantel Pamoate	Dog	10,096	4,386	1	Yes
Albendazole	Cattle	770	5	3	No
Alfaxalone	Dog	1,027	148	1	Yes
Alprazolam	Dog	442	25	None	No
Altrenogest	Human exposure	489	16	6	No
Amantadine	Dog	532	124	None	Yes
Amitraz	Dog	1,105	0	1	No
Amitraz + (S) - methoprene	Dog	462	0	None	No
Amlodipine	Cat	754	114	None	Yes
Amoxicillin	Dog	8,680	186	None	Yes
Amoxicillin + Amoxicillin Trihydrate + Clavulanate Potassium	Dog	256	1	None	No
Amoxicillin + Clavulanate Potassium	Dog	2,378	216	1	Yes
Amoxicillin Trihydrate	Cat	109	6	13	No
Amoxicillin Trihydrate + Clavulanate Potassium	Dog	5,559	373	6	Yes
Ampicillin Sodium	Dog	333	53	2	No
Ampicillin Trihydrate	Dog	652	19	12	No
Amprolium	Cattle	396	11	13	No
Apomorphine	Dog	135	5	None	No
Aspirin	Dog	271	22	None	No
Atenolol	Cat	150	24	None	No
Atinvicitinib	Dog	379	379	1	No
Atipamezole Hydrochloride	Dog	3,952	286	5	Yes
Atropine	Dog	952	62	None	Yes
Attapulgite	Dog	135	14	None	No
Avilamycin	Chicken	59	2	2	No
Azathioprine	Dog	107	4	None	No
Azithromycin	Cat	154	16	None	No
Bacitracin	Dog	417	18	None	No
Bedinvetmab	Dog	19,893	4,339	1	Yes
Benazepril	Dog	589	106	None	Yes
Benazepril hydrochloride	Dog	108	3	None	No
Benazepril hydrochloride + Spironolactone	Dog	78	12	1	No
Betamethasone Acetate + Florfenicol + Terbinafine	Dog	627	60	1	Yes
Betamethasone Acetate + Terbinafine	Dog	65	61	1	No
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	Dog	2,334	17	4	No
Betamethasone Valerate + Gentamicin Sulfate	Dog	386	12	8	No
Bexagliflozin	Cat	4,126	1,153	1	Yes
Bismuth Subsalicylate	Dog	61	4	None	No
Budesonide	Cat	213	44	None	No
Bupivacaine	Dog	1,014	149	1	Yes
Buprenorphine	Cat	7,491	917	2	Yes
Butorphanol Tartrate	Dog	7,724	683	9	Yes
Butorphanol Tartrate + Dexmedetomidine + Ketamine Hydrochloride	Cat	131	16	None	No
Capromorelin	Dog	2,799	439	2	Yes
Carprofen	Dog	52,532	1,848	24	Yes
Cefadroxil	Cat	182	0	2	No
Cefovecin sodium	Cat	13,482	821	3	Yes
Cefpodoxime proxetil	Dog	4,248	340	3	Yes
Ceftiofur Crystalline Free Acid	Cattle	2,159	123	2	Yes
Ceftiofur Hydrochloride	Cattle	1,236	37	5	Yes
Ceftiofur Sodium	Cattle	1,401	63	3	Yes
Cephalexin	Dog	2,858	127	1	Yes
Cephapirin Benzathine	Cattle	438	7	1	No
Cephapirin Sodium	Cattle	860	4	1	No
Cetirizine	Dog	741	72	None	Yes
Chlorambucil	Cat	107	15	None	No
Chloramphenicol	Dog	105	5	17	No
Chlortetracycline	Cattle	125	6	5	No
Chlortetracycline Calcium Complex	Cattle	79	0	3	No
Chlortetracycline Hydrochloride	Cattle	98	1	17	No
Ciclesonide	Horse	302	8	1	No
Ciprofloxacin	Dog	303	22	None	No
Cisapride	Cat	161	29	None	No
Clenbuterol Hydrochloride	Horse	148	3	1	No
Clindamycin	Dog	1,212	119	1	Yes
Clindamycin Hydrochloride	Dog	707	22	9	No
Clodronate	Horse	317	19	1	No
Clomipramine Hydrochloride	Dog	2,457	40	3	Yes
Clonidine	Dog	63	26	None	No
Cloprostenol Sodium	Cattle	223	2	2	No
Clorsulon + Ivermectin	Cattle	939	21	4	No
Clotrimazole + Gentamicin	Dog	1,331	58	None	Yes
Clotrimazole + Gentamicin + Mometasone furoate	Dog	166	2	None	No
Clotrimazole + Gentamicin Sulfate + Mometasone furoate	Dog	163	114	1	No
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate	Dog	1,333	12	1	No
Cloxacillin Benzathine	Cattle	247	5	3	No
Cloxacillin Sodium	Cattle	58	0	1	No
Codeine	Dog	79	15	None	No
Copper Naphthenate	Human exposure	434	3	3	No
Cyclophosphamide	Dog	59	8	None	No
Cyclosporine	Dog	21,715	626	5	Yes
Danofloxacin	Cattle	161	16	1	No
Decoquinate	Cattle	159	1	2	No
Deracoxib	Dog	11,982	94	3	Yes
Deslorelin Acetate	Ferret	391	8	2	No
Desoxycorticosterone Pivalate	Dog	2,502	5	2	No
Detomidine Hydrochloride	Horse	1,304	80	5	Yes
Dexamethasone	Dog	3,041	314	18	Yes
Dexamethasone + Neomycin Sulfate + Thiabendazole	Cat	1,137	174	2	Yes
Dexamethasone + Thiabendazole	Dog	904	17	None	No
Dexamethasone Sodium Phosphate	Dog	864	135	7	Yes
Dexmedetomidine	Dog	2,779	412	1	Yes
Dexmedetomidine hydrochloride	Dog	5,731	334	6	Yes
Dextran	Pig	117	6	1	No
Dextrose	Dog	302	30	None	No
Dextrose + Sodium Chloride	Dog	75	2	None	No
Diazepam	Dog	979	51	1	Yes
Dichlorophene + Toluene	Cat	305	0	17	No
Diclazuril	Horse	181	18	2	No
Diclofenac sodium	Horse	60	4	1	No
Diethylcarbamazine Citrate	Dog	440	0	23	No
Difloxacin Hydrochloride	Dog	91	0	1	No
Diltiazem	Dog	51	8	None	No
Dimethyl Sulfoxide + Fluocinolone Acetonide	Dog	350	11	2	No
Dinoprost Tromethamine	Cattle	1,299	19	4	No
Diphenhydramine	Dog	5,115	501	None	Yes
Dirlotapide	Dog	2,992	0	1	No
Doramectin	Cattle	4,771	72	5	Yes
Doramectin + Levamisole Hydrochloride	Cattle	159	58	None	No
Doxorubicin	Dog	56	8	None	No
Doxycycline	Dog	4,349	513	None	Yes
Doxycycline Hyclate	Dog	126	7	1	No
Emodepside + Praziquantel	Cat	6,144	182	1	Yes
Enalapril Maleate	Dog	2,086	130	1	Yes
Enrofloxacin	Dog	8,078	279	23	Yes
Enrofloxacin + Ketoconazole + Triamcinolone	Dog	101	19	None	No
Enrofloxacin + Silver sulfadiazine	Dog	743	39	2	Yes
Eprinomectin	Cattle	2,269	36	5	Yes
Eprinomectin + Esafoxolaner + Praziquantel	Cat	3,445	1,062	1	Yes
Eprinomectin + Praziquantel	Cat	629	5	1	No
Epsiprantel	Dog	754	12	1	No
Erythromycin	Cat	101	7	5	No
Estradiol	Cattle	431	13	1	No
Estradiol + Trenbolone Acetate	Cattle	267	16	5	No
Estradiol + Tylosin Tartrate	Cattle	74	0	None	No
Estradiol Benzoate + Progesterone	Cattle	290	4	1	No
Estradiol Benzoate + Trenbolone Acetate	Cattle	344	21	2	No
Estriol	Dog	2,054	177	1	Yes
Etodolac	Dog	1,945	0	2	No
Famotidine	Dog	3,067	272	None	Yes
Famphur	Cattle	264	0	3	No
Febantel + Praziquantel + Pyrantel Pamoate	Dog	7,171	426	1	Yes
Fenbendazole	Dog	4,283	189	12	Yes
Fenprostalene	Cattle	57	0	2	No
Fentanyl	Dog	736	45	1	Yes
Fenthion	Dog	234	0	3	No
Firocoxib	Dog	9,582	176	12	Yes
Florfenicol	Cattle	1,082	52	12	Yes
Florfenicol + Flunixin	Cattle	434	7	1	No
Florfenicol + Mometasone furoate + Terbinafine	Dog	5,599	476	4	Yes
Florfenicol + Terbinafine	Dog	2,282	18	None	No
Fluconazole	Dog	344	64	None	No
Flunixin	Cattle	219	19	1	No
Flunixin Meglumine	Horse	1,499	81	13	Yes
Fluoxetine hydrochloride	Dog	3,019	320	1	Yes
Fluralaner	Dog	88,144	9,563	5	Yes
Fluralaner + Moxidectin	Cat	3,964	687	1	Yes
Follicle Stimulating Hormone	Cattle	50	0	2	No
Frunevetmab	Cat	8,249	1,727	1	Yes
Furosemide	Dog	2,555	255	14	Yes
Gabapentin	Dog	11,015	2,223	None	Yes
Gamithromycin	Cattle	460	18	2	No
Gentamicin	Dog	232	59	None	No
Gentamicin Sulfate	Dog	358	19	29	No
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	Dog	1,861	197	1	Yes
Glycopyrrolate	Dog	217	15	2	No
Gonadorelin	Cattle	232	13	2	No
Gonadorelin Hydrochloride	Cattle	95	0	1	No
Grapiprant	Dog	8,457	812	1	Yes
Griseofulvin	Cat	103	0	6	No
Guaifenesin	Dog	107	21	4	No
Hyaluronate Sodium	Horse	1,125	57	7	Yes
Hydrocodone	Dog	364	38	None	No
Hydrocortisone	Dog	179	22	None	No
Hydrocortisone + Ketoconazole	Dog	85	10	None	No
Hydrogen Peroxide	Dog	248	11	1	No
Hydromorphone	Dog	1,352	118	None	Yes
Hydroxyzine	Dog	1,068	37	None	Yes
Ilunocitinib	Dog	2,244	1,666	1	Yes
Imepitoin	Dog	263	87	1	No
Imidacloprid	Dog	7,093	426	1	Yes
Imidacloprid + Moxidectin	Dog	23,348	482	12	Yes
Imidocarb Dipropionate	Dog	190	0	2	No
Insulin	Dog	13,716	833	1	Yes
Insulin Glargine	Cat	69	17	None	No
Isoflupredone Acetate + Neomycin Sulfate + Tetracaine Hydrochloride	Dog	126	8	2	No
Isoflurane	Dog	5,260	610	7	Yes
Itraconazole	Cat	589	56	1	Yes
Ivermectin	Dog	20,136	263	37	Yes
Ivermectin + Praziquantel	Horse	3,393	47	3	Yes
Ivermectin + Praziquantel + Pyrantel Pamoate	Dog	9,010	81	2	Yes
Ivermectin + Pyrantel Pamoate	Dog	162,847	4,550	3	Yes
Ketamine Hydrochloride	Cat	7,297	415	8	Yes
Ketoconazole	Dog	2,472	337	None	Yes
Ketoprofen	Dog	366	7	2	No
Ketoprofen + Tulathromycin	Cattle	271	55	1	No
Lactic Acid + Salicylic Acid	Dog	302	8	None	No
Lactulose	Cat	304	37	None	No
Lasalocid	Cattle	131	2	3	No
Lasalocid sodium	Cattle	251	0	1	No
Levamisole	Cattle	164	0	2	No
Levamisole Hydrochloride	Sheep	98	2	17	No
Levamisole Phosphate	Cattle	85	0	4	No
Levetiracetam	Dog	719	114	None	Yes
Levothyroxine sodium	Dog	3,218	254	2	Yes
Lidocaine	Dog	536	63	None	Yes
Lincomycin Hydrochloride	Pig	135	0	18	No
Lincomycin Hydrochloride Monohydrate + Spectinomycin Sulfate Tetrahydrate	Cattle	226	0	1	No
Loperamide	Dog	71	3	None	No
Lotilaner	Dog	11,724	1,462	2	Yes
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate	Dog	3,399	2,951	2	Yes
Lubabegron	Cattle	92	44	1	No
Lufenuron	Cat	2,371	3	4	No
Lufenuron + Milbemycin Oxime	Dog	27,608	360	1	Yes
Lufenuron + Milbemycin Oxime + Praziquantel	Dog	6,893	747	1	Yes
Lufenuron + Praziquantel	Dog	3,526	0	None	No
Marbofloxacin	Dog	1,848	63	5	Yes
Maropitant	Dog	16,807	1,951	6	Yes
Mebendazole	Dog	50	0	4	No
Mebendazole + Trichlorfon	Horse	75	0	2	No
Meclofenamic Acid	Dog	106	0	2	No
Medetomidine	Dog	2,642	26	1	No
Medetomidine hydrochloride	Dog	66	13	1	No
Medetomidine hydrochloride + Vatinoxan hydrochloride	Dog	568	101	1	Yes
Melarsomine Dihydrochloride	Dog	23,942	696	2	Yes
Melatonin	Dog	283	35	1	No
Melengestrol Acetate	Cattle	776	10	5	No
Meloxicam	Dog	17,324	586	15	Yes
Methadone	Dog	394	129	None	No
Methimazole	Cat	1,283	257	4	Yes
Methocarbamol	Dog	723	72	2	Yes
Methylprednisolone	Dog	307	24	2	No
Methylprednisolone Acetate	Cat	2,321	148	2	Yes
Metoclopramide	Dog	681	89	None	Yes
Metronidazole	Dog	3,699	433	1	Yes
Miconazole Nitrate	Dog	276	45	4	No
Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate	Dog	256	7	1	No
Midazolam	Dog	2,077	267	None	Yes
Milbemycin Oxime	Dog	32,619	383	3	Yes
Milbemycin Oxime + Praziquantel	Dog	33,672	2,240	1	Yes
Milbemycin Oxime + Spinosad	Dog	140,813	659	1	Yes
Minocycline	Dog	118	3	None	No
Mirtazapine	Cat	3,107	790	1	Yes
Misoprostol	Horse	171	41	None	No
Molidustat	Cat	677	224	1	Yes
Mometasone Furoate Monohydrate + Orbifloxacin + Posaconazole	Dog	126	29	1	No
Monensin	Cattle	4,867	147	11	Yes
Monensin + Tylosin	Cattle	79	0	2	No
Monensin + Tylosin Phosphate	Cattle	72	0	3	No
Moxidectin	Dog	58,630	4,428	13	Yes
Moxidectin + Praziquantel	Horse	560	11	1	No
Moxidectin + Pyrantel Pamoate + Sarolaner	Dog	1,191	373	1	Yes
Mupirocin	Dog	222	24	4	No
Mycophenolate	Dog	99	19	None	No
Narasin	Pig	434	23	2	No
Narasin + Nicarbazin	Chicken	311	7	1	No
Neomycin Sulfate + Nystatin	Dog	100	0	None	No
Neomycin Sulfate + Nystatin + Thiostrepton	Dog	63	1	None	No
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide	Dog	997	150	9	Yes
Neomycin Sulfate + Tetracaine Hydrochloride	Dog	111	21	None	No
Nitazoxanide	Horse	84	0	1	No
Nitenpyram	Dog	21,578	1,041	2	Yes
Novobiocin + Penicillin G Procaine	Cattle	54	0	None	No
Nystatin + Thiostrepton + Triamcinolone	Dog	59	16	None	No
Nystatin + Thiostrepton + Triamcinolone Acetonide	Dog	95	16	None	No
Oclacitinib	Dog	30,692	2,947	2	Yes
Omeprazole	Horse	3,868	654	3	Yes
Ondansetron	Dog	887	261	None	Yes
opAFP-GHc2 rDNA construct	Fish	98	0	1	No
Orbifloxacin	Cat	1,514	52	2	Yes
Orbifloxacin + Posaconazole	Dog	344	8	None	No
Ormetoprim + Sulfadimethoxine	Dog	1,147	2	3	No
Oxfendazole	Cattle	301	14	6	No
Oxibendazole	Dog	1,734	0	2	No
Oxytetracycline	Cattle	1,242	13	16	No
Oxytetracycline + Oxytetracycline Dihydrate	Cattle	165	3	None	No
Oxytetracycline + Polymyxin B Sulfate	Cat	389	15	None	No
Oxytetracycline Dihydrate	Cattle	222	13	3	No
Oxytetracycline Hydrochloride	Chicken	432	0	27	No
Oxytocin	Cattle	55	0	10	No
Pegbovigrastim	Cattle	102	0	1	No
Penicillin G Benzathine + Penicillin G Procaine	Dog	310	0	7	No
Penicillin G Procaine	Cattle	729	1	12	No
Pentobarbital	Dog	1,105	2	None	No
Pentobarbital Sodium + Phenytoin Sodium	Dog	607	56	4	Yes
Pentosan polysulfate sodium	Horse	217	81	1	No
Pentoxifylline	Dog	75	22	None	No
Pergolide mesylate	Horse	1,426	119	2	Yes
Phenobarbital	Dog	1,680	116	None	Yes
Phenylbutazone	Horse	230	22	36	No
Phenylpropanolamine hydrochloride	Dog	1,007	184	3	Yes
Pimobendan	Dog	6,809	626	3	Yes
Piperonyl Butoxide	Dog	57	5	None	No
Piperonyl Butoxide + Pyrethrins	Dog	76	1	None	No
Polysulfated Glycosaminoglycan	Dog	5,857	286	3	Yes
Ponazuril	Horse	490	33	1	No
Potassium bromide	Dog	540	30	1	Yes
Potassium Citrate	Dog	92	11	None	No
Pradofloxacin	Cat	653	66	2	Yes
Praziquantel	Cat	4,039	330	7	Yes
Praziquantel + Pyrantel Pamoate	Dog	5,092	206	2	Yes
Prednisolone	Dog	3,368	426	1	Yes
Prednisolone + Trimeprazine Tartrate	Dog	2,092	44	3	Yes
Prednisolone Acetate	Dog	62	9	2	No
Prednisolone Sodium Succinate	Dog	342	0	2	No
Prednisone	Dog	9,632	976	1	Yes
Pregabalin	Cat	221	82	1	No
Primidone	Dog	153	0	5	No
Progesterone	Cattle	840	25	2	No
Propofol	Dog	4,895	491	4	Yes
Pyrantel Pamoate	Dog	5,918	253	16	Yes
Pyrantel Pamoate + Sarolaner	Dog	55,025	10,254	None	Yes
Pyrantel Tartrate	Horse	1,023	1	31	No
Rabacfosadine	Dog	679	28	1	No
Ractopamine Hydrochloride	Cattle	326	0	8	No
Robenacoxib	Cat	3,752	409	5	Yes
Ropinirole	Dog	329	43	1	No
Salicylic Acid	Dog	451	76	1	No
Sarolaner	Dog	17,585	835	1	Yes
Sarolaner + Selamectin	Cat	9,828	1,306	1	Yes
Selamectin	Dog	62,378	819	6	Yes
Selegiline Hydrochloride	Dog	4,507	19	1	No
Sevoflurane	Dog	1,345	80	4	Yes
Sildenafil	Dog	91	15	None	No
Silver sulfadiazine	Dog	92	24	None	No
Sodium Chloride	Dog	5,041	512	None	Yes
Sotalol	Dog	87	9	None	No
Spinosad	Dog	72,836	61	1	Yes
Spironolactone	Dog	220	60	None	No
Stanozolol	Dog	63	0	3	No
Sucralfate	Dog	1,479	311	None	Yes
Sulfadiazine + Trimethoprim	Dog	286	6	11	No
Sulfadimethoxine	Dog	1,705	63	23	Yes
Sulfamethazine	Cattle	110	0	11	No
Telmisartan	Cat	714	68	1	Yes
Tepoxalin	Dog	1,166	0	1	No
Terbinafine	Dog	158	20	None	No
Tetracaine	Dog	120	3	None	No
Tetracycline Hydrochloride	Cat	68	0	26	No
Theophylline	Dog	185	12	None	No
Thiabendazole	Dog	56	0	17	No
Tiamulin	Pig	128	7	1	No
Tiamulin Hydrogen Fumarate	Pig	106	0	9	No
Tigilanol tiglate	Dog	2,050	243	1	Yes
Tildipirosin	Cattle	529	9	1	No
Tiletamine Hydrochloride	Dog	891	37	None	Yes
Tiletamine Hydrochloride + Zolazepam Hydrochloride	Cat	3,149	74	3	Yes
Tilmicosin	Human exposure	501	39	1	Yes
Tilmicosin Phosphate	Human exposure	3,573	0	3	No
Toceranib Phosphate	Dog	1,275	48	1	Yes
Tramadol	Dog	3,821	103	None	Yes
Trazodone	Dog	1,726	390	None	Yes
Triamcinolone	Dog	290	28	1	No
Triamcinolone Acetonide	Dog	1,448	20	9	No
Trilostane	Dog	12,213	731	1	Yes
Trimethoprim	Dog	181	21	None	No
Tulathromycin	Cattle	3,191	149	17	Yes
Tylosin	Dog	1,191	30	7	Yes
Tylosin Phosphate	Cattle	231	18	58	No
Tylosin Tartrate	Dog	521	34	4	Yes
Ursodiol	Dog	780	99	None	Yes
Velagliflozin	Cat	5,131	1,940	1	Yes
Verdinexor	Dog	436	49	1	No
Vincristine	Dog	88	15	None	No
Virginiamycin	Cattle	70	1	8	No
Vitamin D	Human exposure	64	10	None	No
Vitamin E	Dog	1,191	15	None	No
Xylazine	Horse	1,128	42	1	Yes
Xylazine Hydrochloride	Horse	131	22	7	No
Zeranol	Cattle	596	4	2	No
Zilpaterol	Cattle	90	0	None	No
Zonisamide	Dog	321	38	None	No

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The last column is the number of approved applications with exactly that set of ingredients.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Sets with 20 to 49 reports

Related lists

Brand names A to ZEach brand name opens the page of its active ingredients
Ingredients, all combinationsOne ingredient in every combination that the reports name