Pyrantel Pamoate (Nemex, Nemex-2): adverse event reports that FDA received

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 5,918 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

1. Vomiting22.3%1,317 reports
2. Diarrhoea[diarrhea]12.9%761 reports
3. Death11.4%674 reports
4. Lethargy[unusually tired or inactive]11.3%671 reports
5. Anorexia[not eating]8.6%507 reports
6. Depression[dull, quiet or withdrawn]7.4%437 reports
7. Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]7.4%436 reports
8. No sign[no clinical sign was reported]4.7%280 reports
9. Accidental exposure[exposure that was not intended]4%236 reports
10. Emesis[vomiting]3.9%229 reports
11. Ataxia[unsteady, uncoordinated movement]3.5%207 reports
12. Facial swelling3.2%191 reports
13. Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]3.1%183 reports
14. Anaphylaxis[sudden severe allergic-type reaction]2.7%159 reports

The list shows 30 of 1,274 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

• Dog80.6%4,771
• Cat9.4%559
• Horse3.5%209
• Human exposure1.5%86
• Other0.4%23
• Goatunder 0.1%2

The share is of all 5,918 reports that name pyrantel pamoate. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

• Dog
• Cat
• Horse
• Other or not given

2026 has the reports that FDA received through Jun 2026. Download the years (CSV)

What the reports record

Each bar is on a scale of 0 to 100%.

Other pages with this ingredient

A report names a drug by its set of active ingredients. Each set has its own page. The list is in order of name.

• Pyrantel Pamoate, all combinations
• Afoxolaner + Moxidectin + Pyrantel Pamoate
• Febantel + Praziquantel + Pyrantel Pamoate
• Ivermectin + Praziquantel + Pyrantel Pamoate
• Ivermectin + Pyrantel Pamoate
• Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate
• Moxidectin + Pyrantel Pamoate + Sarolaner
• Praziquantel + Pyrantel Pamoate
• Pyrantel Pamoate + Sarolaner

Next in the A to Z list

• Pregabalin
• Primidone
• Progesterone
• Propofol
• Pyrantel Tartrate
• Rabacfosadine
• Ractopamine Hydrochloride

All drugs by active ingredient. Brand names A to Z

FDA pages for this drug

• How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
• Green Book record of NADA 100-237The FDA record of the application for Nemex, Nemex-2, RFD Liquid Wormer.
• Green Book record of NADA 101-331The FDA record of the application for Dog Wormer Tablets.
• Green Book record of NADA 139-191The FDA record of the application for Adams, D-Worm, Dog Wormer Chewable Tablets.
• Green Book record of ANADA 200-007The FDA record of the application for Liqui-Vict 2X.
• Green Book record of ANADA 200-248The FDA record of the application for Pyrantel Pamoate Suspension, Pyrantel Pamoate Suspension-2.27mg, Pyrantel Pamoate Suspension-4.54mg.
• Green Book record of ANADA 200-281The FDA record of the application for Pyrantel Pamoate Chewable Tablets.
• Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Pet Drug Reports. Pyrantel Pamoate: adverse event reports that FDA received. https://petdrugreports.com/drug/pyrantel-pamoate/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists the brand names with this active ingredient.

Do the reports show that the drug caused the signs?

No. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 253 reports in the 12 months to June 2026. It received 199 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 5,918 reports received from August 1987 to June 2026, 80.6% are about a safety issue only. 14.3% are about a lack of expected effectiveness, alone or with a safety issue. 5% are about a defect of the product or its package.