Pet Drug Reports

Oxytetracycline Dihydrate (Noromycin 300 LA, Agrimycin 200)adverse event reports that FDA received

Active ingredient

Also sold as: Noromycin 300 LA, Agrimycin 200, Terramycin.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From December 2012 to April 2026, FDA received 222 adverse event reports that name a drug with oxytetracycline dihydrate as its active ingredient. Of the 222 reports, 88 (39.6%) are about cattle. 15 reports are about people who were exposed to the drug (6.8%).

In January to March 2026, FDA received 4 reports that name this drug. The signs that appear in the largest number of the 222 reports are "Vials, Damaged", "Death" and "Lack of efficacy - NOS". A report is not proof that a drug caused a sign.

Fewer than 20 reports named this drug in the 12 months before June 2026, so this page gives no change. Reports about cattle are 39.6% of the reports that name this drug, and 2.3% of all reports.

Search engines list a drug page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Since the last update of the FDA data

The latest update of the FDA data, recorded on , changed no count of this page.

January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 4 reports that name oxytetracycline dihydrate: 0 dog, 0 cat, 0 horse, 4 other or not given.

All updatesFeed of updates (RSS)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 222 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

  1. Vials, Damaged[a product quality report, not a sign in an animal]23.4%52 reports
  2. Death19.8%44 reports
  3. Lack of efficacy - NOS[the product did not have the expected effect]7.2%16 reports
  4. Bottles, Damaged[a product quality report, not a sign in an animal]6.8%15 reports
  5. Injection site swelling[swelling where the injection was given]6.8%15 reports
  6. Anaphylaxis[sudden severe allergic-type reaction]5.9%13 reports
  7. Appearance, Abnormal[a product quality report, not a sign in an animal]4.1%9 reports
  8. Containers, Leaking[a product quality report, not a sign in an animal]4.1%9 reports
  9. Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]3.2%7 reports
  10. Product Defect, General[a product quality report, not a sign in an animal]3.2%7 reports
  11. Accidental exposure[exposure that was not intended]2.7%6 reports
  12. Collapse NOS[NOS: not otherwise specified]2.7%6 reports
  13. Color, Abnormal[a product quality report, not a sign in an animal]2.7%6 reports
  14. Foaming at the mouth2.7%6 reports
Show the next 16 signs
  1. Anaphylactic-type reaction2.3%5 reports
  2. Behavioural disorder NOS[behaviour change, type not specified]2.3%5 reports
  3. Death by euthanasia[the animal was euthanized]2.3%5 reports
  4. Injection site pain[pain where the injection was given]2.3%5 reports
  5. Medication error2.3%5 reports
  6. Sudden death2.3%5 reports
  7. Anorexia[not eating]1.8%4 reports
  8. Collapse1.8%4 reports
  9. Containers, Damaged[a product quality report, not a sign in an animal]1.8%4 reports
  10. Injection site bleeding[bleeding where the injection was given]1.8%4 reports
  11. Injection site inflammation[inflammation where the injection was given]1.8%4 reports
  12. Abortion1.4%3 reports
  13. Defect Unknown/Not Specified[a product quality report, not a sign in an animal]1.4%3 reports
  14. Heavy breathing1.4%3 reports
  15. Hyperthermia[raised body temperature]1.4%3 reports
  16. Ineffective, antibiotic[legacy FDA term: the product did not have the expected effect (antibiotic)]1.4%3 reports

The list shows 30 of 175 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

The share is of all 222 reports that name oxytetracycline dihydrate. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

Dog4 reports

No chart: no month has 5 or more reports.

Cat1 report

No chart: no month has 5 or more reports.

Horse5 reports

No chart: no month has 5 or more reports.

Other or not given91 reports. Largest count in one month: 6 (Jul 2024)

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

  • Dog
  • Cat
  • Horse
  • Other or not given
Reports that name oxytetracycline dihydrate, by the year in which FDA received them and by species
YearDogCatHorseOther or not givenAll species
202600055
20250011112
20240101920
20232001820
20221042429
20211012325
20201013234
20190014142
20180001616
201720158
201600022
201500123
201400022
201300033
201200011

2026 has the reports that FDA received through Apr 2026. Download the years (CSV)

What the reports record

Outcome at the time of the report

  • Recovered/Normal18.9%42
  • Recovered with Sequela[recovered, with a lasting effect]0.5%1
  • Ongoing3.2%7
  • Died22.1%49
  • Euthanized2.3%5
  • Outcome Unknown18.9%42

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 222 reports that name oxytetracycline dihydrate.

A report about more than one animal can have more than one outcome.

Kind of report

  • Safety issue45.9%102
  • Lack of expected effectiveness8.1%18
  • Both safety and lack of expected effectiveness2.3%5
  • Manufacturing or product defect43.7%97
  • Other0%0

126 reports say if the event was serious. 65.1% of them have the serious flag. The person who sends the report sets the flag.

Show age, weight, breed and route

Age of the animal

  • Under 1 year12.6%28
  • 1 to 3 years13.5%30
  • 4 to 7 years3.2%7
  • 8 to 11 years2.7%6
  • 12 years and over8.1%18
  • Age not given59.9%133

Weight of the animal

  • Under 5 kg (11 lb)0.9%2
  • 5 to 9.9 kg (11 to 22 lb)1.4%3
  • 10 to 24.9 kg (22 to 55 lb)1.4%3
  • 25 to 44.9 kg (55 to 99 lb)0%0
  • 45 kg and over (99 lb and over)36.5%81
  • Weight not given59.9%133

Breed, where the report gives one breed

A breed with many animals has many reports.

Route in the report

  • Subcutaneous18.5%41
  • Intramuscular11.7%26
  • Intravenous2.7%6
  • Oral1.8%4
  • Parenteral1.4%3
  • Cutaneous0.5%1

Each bar is on a scale of 0 to 100%.

Approved animal drugs with this active ingredient (FDA Green Book)

This section is reference data. It has no report count.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Brand names

  • Noromycin 300 LA
  • Agrimycin 200
  • Terramycin

What the Green Book records give

Applications with an approval in force
3
Approved species
Cattle, Crustaceans, Fish, Swine
Dose forms
Type A Medicated Article, Injectable Solution, Solution
Routes
Intramuscular, Intravenous, Oral, Subcutaneous
Sale
RX (prescription), VFD (veterinary feed directive)
Earliest approval date in the records

The species, dose forms and routes are the words of the Green Book records for all the applications together. One product can have fewer. The label of a product gives its approved use.

Applications in the Green Book of 2 Nov 2026, pioneer applications (NADA) first
Brand nameActive ingredientsSponsorApproved speciesApplication
Terramycin 100 for Fish; Terramycin 200 for FishOxytetracycline DihydratePhibro Animal Health Corp.Not in the list of major speciesNADA 038-439
Noromycin 300 LAOxytetracycline DihydrateNorbrook Laboratories, Ltd.Cattle, SwineNADA 141-143
Agrimycin 200Oxytetracycline DihydrateHuvepharma EOODCattle, SwineANADA 200-128

Other pages with this ingredient

A report names a drug by its set of active ingredients. Each set has its own page. The list is in order of name.

Next in the A to Z list

All drugs by active ingredient. Brand names A to Z

FDA pages for this drug

The site checked these addresses on . The links open in a new tab.

Cite this page

Pet Drug Reports. Oxytetracycline Dihydrate: adverse event reports that FDA received. https://petdrugreports.com/drug/oxytetracycline-dihydrate/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists the brand names with this active ingredient.

Do the reports show that the drug caused the signs?

No. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 13 reports in the 12 months to June 2026. It received 17 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 222 reports received from December 2012 to April 2026, 45.9% are about a safety issue only. 10.4% are about a lack of expected effectiveness, alone or with a safety issue. 43.7% are about a defect of the product or its package.