Oxibendazole (Anthelcide EQ): adverse event reports that FDA received

Name: Oxibendazole: adverse event reports that FDA received, by year and species
Creator: Pet Drug Reports
License: https://creativecommons.org/publicdomain/zero/1.0/

Active ingredient

The name in brackets is a brand name with this active ingredient.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From January 1987 to February 2022, FDA received 1,734 adverse event reports that name a drug with oxibendazole as its active ingredient. Of the 1,734 reports, 1,294 (74.6%) are about dogs. 209 reports are about horses (12.1%).

In January to March 2026, FDA received no reports that name this drug. The signs that appear in the largest number of the 1,734 reports are "Vomiting", "Elevated alanine aminotransferase (ALT)" and "Anorexia". A report is not proof that a drug caused a sign.

Fewer than 20 reports named this drug in the 12 months before June 2026, so this page gives no change. Reports about horses are 12.1% of the reports that name this drug, and 1.4% of all reports.

Search engines list a drug page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Since the last update of the FDA data

The latest update of the FDA data, recorded on 11 Oct 2026, changed no count of this page.

January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 0 reports that name oxibendazole: 0 dog, 0 cat, 0 horse, 0 other or not given.

All updates Feed of updates (RSS)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 1,734 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

Vomiting17.1%296 reports
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]14.5%251 reports
Anorexia[not eating]13.6%235 reports
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]12.7%220 reports
Depression[dull, quiet or withdrawn]12%208 reports
Diarrhoea[diarrhea]11.6%201 reports
No sign[no clinical sign was reported]9.8%170 reports
Accidental exposure[exposure that was not intended]9.3%162 reports
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]9.2%160 reports
Death8%139 reports
Unpalatable[legacy FDA term: the animal would not take it]6.9%120 reports
Abdominal pain6.5%112 reports
Elevated total bilirubin[bilirubin above the normal range]5.7%99 reports
PR-liver, lesion(s)[legacy FDA term: lesions found in the liver]5.7%99 reports

Show the next 16 signs

Elevated aspartate aminotransferase (AST)[a liver and muscle enzyme above the normal range]5.7%98 reports
Icterus[jaundice (yellowing)]5.1%89 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.3%74 reports
Weight loss3.5%60 reports
Elevated liver enzymes[liver enzymes above the normal range]3.2%55 reports
Hypoalbuminaemia[low blood albumin]2.9%50 reports
Leucocytosis NOS[high white blood cell count]2.8%49 reports
Anaemia NOS[low red blood cell count]2.7%46 reports
Convulsion[seizure]2.7%46 reports
Fever2.7%46 reports
Death by euthanasia[the animal was euthanized]2.5%44 reports
Polydipsia[drinking more than usual]2.5%43 reports
Unclassifiable adverse event[event that fits no dictionary term]2.5%43 reports
Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]2.2%38 reports
Polyuria[passing more urine than usual]2.1%37 reports
Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]2.1%36 reports

The list shows 30 of 348 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

Dog74.6%1,294
Horse12.1%209
Human exposure2.4%42
Cat1.6%28
Other0.2%3
Cattle0.1%1

The share is of all 1,734 reports that name oxibendazole. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

Dog0 reports

No chart: no month has 5 or more reports.

Cat0 reports

No chart: no month has 5 or more reports.

Horse0 reports

No chart: no month has 5 or more reports.

Other or not given1 report

No chart: no month has 5 or more reports.

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

Dog
Cat
Horse
Other or not given

Reports that name oxibendazole, by the year in which FDA received them and by species
Year	Dog	Cat	Horse	Other or not given	All species
2022	0	0	0	1	1
2021	1	0	0	0	1
2012	0	0	1	0	1
2011	0	0	4	2	6
2010	0	0	3	2	5
2009	0	0	9	2	11
2008	0	0	17	1	18
2007	1	0	8	1	10
2006	0	0	10	1	11
2005	0	0	14	1	15
2004	12	0	3	4	19
2003	14	0	3	6	23
2002	24	0	3	6	33
2001	45	0	6	20	71
2000	72	2	5	86	165
1999	113	5	5	20	143
1998	88	4	7	12	111
1997	39	3	7	7	56
1996	52	0	10	4	66
1995	64	6	10	7	87
1994	80	3	10	7	100
1993	82	4	11	5	102
1992	79	0	9	5	93
1991	68	0	12	3	83
1990	66	0	11	0	77
1989	85	0	14	0	99
1988	136	1	8	0	145
1987	173	0	9	0	182

2022 has the reports that FDA received through Feb 2022. Download the years (CSV)

What the reports record

Outcome at the time of the report

Recovered/Normal0%0
Recovered with Sequela[recovered, with a lasting effect]0%0
Ongoing0%0
Died10.3%178
Euthanized0%0
Outcome Unknown0.1%1

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 1,734 reports that name oxibendazole.

A report about more than one animal can have more than one outcome.

Kind of report

Safety issue91.1%1,580
Lack of expected effectiveness0%0
Both safety and lack of expected effectiveness0%0
Manufacturing or product defect8.9%154
Other0%0

1 reports say if the event was serious. 100% of them have the serious flag. The person who sends the report sets the flag.

Show age, weight, breed and route

Age of the animal

Under 1 year9.4%163
1 to 3 years18.1%314
4 to 7 years19.2%333
8 to 11 years13.5%234
12 years and over7.8%135
Age not given32%555

Weight of the animal

Under 5 kg (11 lb)5.2%91
5 to 9.9 kg (11 to 22 lb)10.3%179
10 to 24.9 kg (22 to 55 lb)20%347
25 to 44.9 kg (55 to 99 lb)21.7%377
45 kg and over (99 lb and over)8.5%148
Weight not given34.1%592

Breed, where the report gives one breed

A breed with many animals has many reports.

Route in the report

Oral90.4%1,568
Topical0.1%1

Each bar is on a scale of 0 to 100%.

Approved animal drugs with this active ingredient (FDA Green Book)

This section is reference data. It has no report count.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Brand names

Anthelcide EQ

What the Green Book records give

Applications with an approval in force: 2
Approved species: Equids
Dose forms: Liquid (Suspension), Paste
Routes: Oral
Sale: OTC (over the counter), RX (prescription)

The species, dose forms and routes are the words of the Green Book records for all the applications together. One product can have fewer. The label of a product gives its approved use.

Applications in the Green Book of 2 Nov 2026, pioneer applications (NADA) first
Brand name	Active ingredients	Sponsor	Approved species	Application
Anthelcide EQ Suspension	Oxibendazole	Zoetis Inc.	Horses	NADA 109-722
Anthelcide EQ Paste	Oxibendazole	Zoetis Inc.	Horses	NADA 121-042

Next in the A to Z list

All drugs by active ingredient. Brand names A to Z

FDA pages for this drug

How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
Green Book record of NADA 109-722The FDA record of the application for Anthelcide EQ Suspension.
Green Book record of NADA 121-042The FDA record of the application for Anthelcide EQ Paste.
Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Pet Drug Reports. Oxibendazole: adverse event reports that FDA received. https://petdrugreports.com/drug/oxibendazole/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

Which brand are these reports about?: The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists the brand names with this active ingredient.
Do the reports show that the drug caused the signs?: No. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
How many reports did FDA receive in the latest 12 months?: FDA received no reports in the 12 months to June 2026. It received no reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
What kinds of report are in the count?: Of the 1,734 reports received from January 1987 to February 2022, 91.1% are about a safety issue only. 8.9% are about a defect of the product or its package.