Pet Drug Reports

Vitamin E: adverse event reports that FDA received

Active ingredient

The Green Book lists no brand name for exactly this active ingredient.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From March 1987 to June 2026, FDA received 1,191 adverse event reports that name a drug with vitamin e as its active ingredient. Of the 1,191 reports, 655 (55%) are about dogs. 255 reports are about cattle (21.4%).

In January to March 2026, FDA received 5 reports that name this drug. The signs that appear in the largest number of the 1,191 reports are "Death", "Elevated alanine aminotransferase (ALT)" and "Vomiting". A report is not proof that a drug caused a sign.

Reports that name this drug fell by 44.4% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about cattle are 21.4% of the reports that name this drug, and 2.3% of all reports.

Search engines list a drug page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Since the last update of the FDA data

The latest update of the FDA data, recorded on , changed no count of this page.

January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 5 reports that name vitamin e: 3 dog, 0 cat, 0 horse, 2 other or not given.

All updatesFeed of updates (RSS)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 1,191 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

  1. Death21.8%260 reports
  2. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]21.2%253 reports
  3. Vomiting18.4%219 reports
  4. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]16.1%192 reports
  5. Lethargy[unusually tired or inactive]15.9%189 reports
  6. Anorexia[not eating]14.9%177 reports
  7. Elevated total bilirubin[bilirubin above the normal range]12.5%149 reports
  8. Anaphylaxis[sudden severe allergic-type reaction]12.2%145 reports
  9. Elevated liver enzymes[liver enzymes above the normal range]11.2%133 reports
  10. Other abnormal test result NOS[abnormal laboratory result, type not specified]9.2%109 reports
  11. Death by euthanasia[the animal was euthanized]8.9%106 reports
  12. Diarrhoea[diarrhea]8.6%103 reports
  13. Weight loss7.5%89 reports
Show the next 16 signs
  1. Icterus[jaundice (yellowing)]5.9%70 reports
  2. Ataxia[unsteady, uncoordinated movement]5.7%68 reports
  3. Collapse5.7%68 reports
  4. Dyspnoea[difficulty breathing]5.7%68 reports
  5. Decreased appetite5.5%66 reports
  6. Depression[dull, quiet or withdrawn]5%60 reports
  7. Leucocytosis NOS[high white blood cell count]4.9%58 reports
  8. Elevated gamma-glutamyl transferase (GGT)[a liver enzyme above the normal range]4.8%57 reports
  9. Elevated aspartate aminotransferase (AST)[a liver and muscle enzyme above the normal range]4.5%53 reports
  10. Elevated creatinine[a kidney value above the normal range]4.4%52 reports
  11. Emesis[vomiting]4.4%52 reports
  12. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]4.3%51 reports
  13. Not eating4.1%49 reports
  14. Recumbency[lying down and unable or unwilling to rise]3.9%47 reports
  15. Seizure NOS[seizure, type not specified]3.8%45 reports
  16. Anaemia NOS[low red blood cell count]3.7%44 reports

The list shows 30 of 867 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

The share is of all 1,191 reports that name vitamin e. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

Dog87 reports. Largest count in one month: 6 (Jul 2021)
Cat5 reports

No chart: no month has 5 or more reports.

Horse10 reports

No chart: no month has 5 or more reports.

Other or not given14 reports. Largest count in one month: 5 (Jul 2023)

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

  • Dog
  • Cat
  • Horse
  • Other or not given
Reports that name vitamin e, by the year in which FDA received them and by species
YearDogCatHorseOther or not givenAll species
2026810312
20251810019
20241515223
20231422624
20221802323
20213501440
20204722152
20193520138
20185310458
20176520269
20167662286
20156651072
2014814312100
201370512096
20124725761
201100347
201000066
200910168
20080021416
20071021013
20061012527
2005005712
20040081119
2003006410
20020011314
2001003710
2000007512
199900132336
1998005712
199700111021
19960031417
19950052227
1994009918
19932071221
199210121326
19911031418
19900071320
19890022224
19880051015
198700819

2026 has the reports that FDA received through Jun 2026. Download the years (CSV)

What the reports record

Outcome at the time of the report

  • Recovered/Normal10.3%123
  • Recovered with Sequela[recovered, with a lasting effect]0.8%9
  • Ongoing27.7%330
  • Died23.2%276
  • Euthanized8.8%105
  • Outcome Unknown10%119

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 1,191 reports that name vitamin e.

A report about more than one animal can have more than one outcome.

Kind of report

  • Safety issue91.6%1,091
  • Lack of expected effectiveness2.9%35
  • Both safety and lack of expected effectiveness3.3%39
  • Manufacturing or product defect2%24
  • Other0.2%2

721 reports say if the event was serious. 47% of them have the serious flag. The person who sends the report sets the flag.

Show age, weight, breed and route

Age of the animal

  • Under 1 year6.4%76
  • 1 to 3 years11.8%140
  • 4 to 7 years19.5%232
  • 8 to 11 years23.4%279
  • 12 years and over19.6%234
  • Age not given19.3%230

Weight of the animal

  • Under 5 kg (11 lb)6%71
  • 5 to 9.9 kg (11 to 22 lb)13.5%161
  • 10 to 24.9 kg (22 to 55 lb)14%167
  • 25 to 44.9 kg (55 to 99 lb)21.6%257
  • 45 kg and over (99 lb and over)28.5%340
  • Weight not given16.4%195

Breed, where the report gives one breed

A breed with many animals has many reports.

Route in the report

  • Oral26.4%314
  • Intramuscular22.3%265
  • Subcutaneous6.8%81
  • Intravenous3.9%46
  • Topical0.8%9
  • Other0.3%4

Each bar is on a scale of 0 to 100%.

Approved animal drugs with this active ingredient (FDA Green Book)

This section is reference data. It has no report count.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

No approved product has exactly this set of active ingredients. The ingredient field of a report can be incomplete. The approved products below have all the ingredients of this page and one or more other ingredients.

Applications in the Green Book of 2 Nov 2026, pioneer applications (NADA) first
Brand nameActive ingredientsSponsorApproved speciesApplication
BO-SESodium Selenite, Vitamin EIntervet, Inc.Cattle, Swine, SheepNADA 012-635
Seletoc Minicaps and CapsSodium Selenite, Vitamin EIntervet, Inc.DogsNADA 030-313
Mu-SeSodium Selenite, Vitamin EIntervet, Inc.CattleNADA 030-314
E-SESodium Selenite, Vitamin EIntervet, Inc.HorsesNADA 030-315
Seletoc InjectionSodium Selenite, Vitamin EIntervet, Inc.DogsNADA 030-316
VeleniumSodium Selenite, Vitamin EZoetis Inc.CattleANADA 200-109
Tylan Plus Vitaminsapproval withdrawnFolic Acid, Pyridoxine Hydrochloride, Tylosin, Vitamin A, Vitamin B1, Vitamin B2, Vitamin B5, Vitamin D, Vitamin EElanco Animal Health, A Division of Eli Lilly & Co.Not in the list of major speciesNADA 013-029

Next in the A to Z list

All drugs by active ingredient. Brand names A to Z

FDA pages for this drug

The site checked these addresses on . The links open in a new tab.

Cite this page

Pet Drug Reports. Vitamin E: adverse event reports that FDA received. https://petdrugreports.com/drug/vitamin-e/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book lists no brand name for exactly this active ingredient.

Do the reports show that the drug caused the signs?

No. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 15 reports in the 12 months to June 2026. It received 27 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 1,191 reports received from March 1987 to June 2026, 91.6% are about a safety issue only. 6.2% are about a lack of expected effectiveness, alone or with a safety issue. 2% are about a defect of the product or its package.