Carprofen (Rimadyl, Vetprofen): adverse event reports that FDA received

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 52,532 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

1. Vomiting24.5%12,887 reports
2. Anorexia[not eating]18.8%9,854 reports
3. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]16.5%8,692 reports
4. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]14.5%7,621 reports
5. Depression[dull, quiet or withdrawn]11.9%6,234 reports
6. Accidental exposure[exposure that was not intended]11.6%6,103 reports
7. Diarrhoea[diarrhea]10%5,252 reports
8. Elevated total bilirubin[bilirubin above the normal range]8.5%4,457 reports
9. Death by euthanasia[the animal was euthanized]8.4%4,417 reports
10. Death8.3%4,346 reports
11. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]6.8%3,593 reports
12. Lethargy[unusually tired or inactive]6.8%3,582 reports
13. No sign[no clinical sign was reported]6.4%3,374 reports
14. Elevated creatinine[a kidney value above the normal range]6%3,132 reports

The list shows 30 of 2,193 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

• Dog90.1%47,325
• Cat3.3%1,711
• Human exposure1.6%844
• Other0.1%46
• Pigunder 0.1%9
• Rabbitunder 0.1%9

The share is of all 52,532 reports that name carprofen. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

• Dog
• Cat
• Horse
• Other or not given

2026 has the reports that FDA received through Jun 2026. Download the years (CSV)

What the reports record

Each bar is on a scale of 0 to 100%.

Next in the A to Z list

• Buprenorphine
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• Capromorelin
• Cefadroxil
• Cefovecin sodium
• Cefpodoxime proxetil
• Ceftiofur Crystalline Free Acid

All drugs by active ingredient. Brand names A to Z

FDA pages for this drug

• How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
• Green Book record of NADA 141-053The FDA record of the application for Rimadyl Caplets.Client Information Sheet of Rimadyl Caplets (PDF): a label document that FDA posts with the record.Package Insert of Rimadyl Caplets (PDF): a label document that FDA posts with the record.
• Green Book record of NADA 141-111The FDA record of the application for Rimadyl Chewable Tablets.Client Information Sheet of Rimadyl Chewable Tablets (PDF): a label document that FDA posts with the record.Package Insert of Rimadyl Chewable Tablets (PDF): a label document that FDA posts with the record.
• Green Book record of NADA 141-199The FDA record of the application for Rimadyl Sterile Injectable Solution.Package Insert of Rimadyl Sterile Injectable Solution (PDF): a label document that FDA posts with the record.
• Green Book record of ANADA 200-397The FDA record of the application for Vetprofen.Package Insert of Vetprofen (PDF): a label document that FDA posts with the record.Client Information Sheet of Vetprofen (PDF): a label document that FDA posts with the record.
• Green Book record of ANADA 200-490The FDA record of the application for Carprofen.
• Green Book record of ANADA 200-498The FDA record of the application for Carprieve.Client Information Sheet of Carprieve (PDF): a label document that FDA posts with the record.Package Insert of Carprieve (PDF): a label document that FDA posts with the record.
• Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Pet Drug Reports. Carprofen: adverse event reports that FDA received. https://petdrugreports.com/drug/carprofen/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists the brand names with this active ingredient.

Do the reports show that the drug caused the signs?

No. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 1,848 reports in the 12 months to June 2026. It received 2,258 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 52,532 reports received from February 1997 to June 2026, 91.9% are about a safety issue only. 3% are about a lack of expected effectiveness, alone or with a safety issue. 5.1% are about a defect of the product or its package.