Drugs by active ingredient

Monthly reports by species, five years

Reports by the month FDA received them. Each panel has its own scale; the peak month is printed at the top right. The newest months are incomplete because FDA posts reports with a delay of three to six months.

Reports by year received

2026 covers reports received through March 2026 only.

Signs listed in reports

share of gentamicin sulfate reports listing the termall drugs containing gentamicin sulfateall dog reports

1. Lethargy[unusually tired or inactive]9.6%34
2. Vomiting9.3%33
3. Death9.1%32
4. Emesis[vomiting]6.2%22
5. Anorexia[not eating]5.9%21
6. Other abnormal test result NOS[abnormal laboratory result, type not specified]5.9%21
7. Ataxia[unsteady, uncoordinated movement]5.4%19
8. Lack of efficacy - NOS[the product did not have the expected effect]5.4%19
9. Diarrhoea[diarrhea]5.1%18
10. Abdominal pain4.8%17
11. Depression[dull, quiet or withdrawn]4.2%15
12. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]4.2%15
13. Elevated creatinine[a kidney value above the normal range]4.2%15
14. Weight loss4%14
15. Administration device NOS, malfunction3.7%13
16. Corneal ulcer3.7%13
17. Death by euthanasia[the animal was euthanized]3.7%13
18. Behavioural disorder NOS[behaviour change, type not specified]3.4%12
19. Colic3.1%11
20. Shaking3.1%11
21. Decreased appetite2.8%10
22. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]2.8%10
23. Fever2.8%10
24. Loose stool2.8%10
25. Solution, Abnormal[a product quality report, not a sign in an animal]2.8%10
26. Tachycardia[fast heart rate]2.8%10
27. Anaemia NOS[low red blood cell count]2.5%9
28. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]2.5%9
29. Increased sweating2.5%9
30. Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]2.5%9

Top 30 of 553 coded terms (VeDDRA, the veterinary reporting dictionary; plain-language gloss in brackets). One report can list several terms. The ticks show how often the same term appears in a wider pool of reports; they describe the reports, and FDA cautions that such figures cannot be used to estimate risk or to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Outcomes and report types

Coloured bar: reports naming gentamicin sulfate. Grey bar: all 1,357,245 reports in the database. Outcomes are the status at the time of the last report, as stated by the reporter; a report covering several animals can carry more than one outcome. FDA has not necessarily determined whether any drug played a part in any outcome.

Species and breeds in the reports

Breed shares follow how common each breed is. Crossbred animals and reports with no breed stay in the species figure only.

Age, weight and route

Route of administration stated in reports: intravenous (59), topical (51), auricular (otic) (28), intramuscular (19), ophthalmic (16), subcutaneous (14).

In context

The gentamicin sulfate pool is every report naming gentamicin sulfate alone or in any combination; this single-ingredient set accounts for 5.5% of it. Shares are of reports, not of animals treated. The number of doses sold is not public, so none of these figures is a rate of occurrence, and differences between columns reflect which animals receive a drug and who reports as much as anything else.

Other ingredient sets sharing an ingredient

Listed for navigation, ordered by report count. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another": drugs differ in formulation, in the animals they are given to, in sales volume and in years on the market. A report's ingredient field can be incomplete, so reports about one product may sit under more than one set.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Drug entries are grouped by the active ingredients their unmasked ingredient field discloses; the application number that records also carry is not used. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.