Pet Drug Reports

Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfateadverse event reports that FDA received

Combination of 3 active ingredients

The Green Book lists no brand name for exactly these active ingredients.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From September 2014 to April 2026, FDA received 32 adverse event reports that name this drug. Its active ingredients are dexamethasone, neomycin sulfate and polymyxin b sulfate. Of the 32 reports, 30 (93.8%) are about dogs. 2 reports are about cats (6.3%).

In January to March 2026, FDA received 1 report that names this drug. The signs that appear in the largest number of the 32 reports are "Other abnormal test result NOS", "Ocular discharge" and "Vomiting". A report is not proof that a drug caused a sign.

Fewer than 20 reports named this drug in the 12 months before June 2026, so this page gives no change. Reports about dogs are 93.8% of the reports that name this drug, and 72.6% of all reports.

Search engines list a drug page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Since the last update of the FDA data

The latest update of the FDA data, recorded on , changed no count of this page.

January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 1 report that names dexamethasone + neomycin sulfate + polymyxin b sulfate: 1 dog, 0 cat, 0 horse, 0 other or not given.

All updatesFeed of updates (RSS)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 32 reports that list the sign. One report can list more than one sign.

The sign that is in the largest number of the reports comes first.

  1. Other abnormal test result NOS[abnormal laboratory result, type not specified]25%8 reports
  2. Ocular discharge21.9%7 reports
  3. Vomiting18.8%6 reports
  4. Erythema (for urticaria see Immune SOC)15.6%5 reports
  5. Lethargy[unusually tired or inactive]15.6%5 reports
  6. Conjunctivitis12.5%4 reports
  7. Crust12.5%4 reports
  8. Decreased appetite12.5%4 reports
  9. Lack of efficacy - NOS[the product did not have the expected effect]12.5%4 reports
  10. Not eating12.5%4 reports
  11. Squinting12.5%4 reports
  12. Thrombocytopenia[low platelet count]12.5%4 reports
  13. Vestibular disorder NOS[NOS: not otherwise specified]12.5%4 reports
  14. Abnormal cytology9.4%3 reports
Show the next 16 signs
  1. Alopecia local9.4%3 reports
  2. Deafness9.4%3 reports
  3. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]9.4%3 reports
  4. Keratoconjunctivitis sicca9.4%3 reports
  5. Lameness9.4%3 reports
  6. Nasal discharge9.4%3 reports
  7. Neutrophilia[high neutrophil count]9.4%3 reports
  8. Otorrhoea9.4%3 reports
  9. Respiratory tract infection NOS[NOS: not otherwise specified]9.4%3 reports
  10. Scale9.4%3 reports
  11. Unable to walk9.4%3 reports
  12. Uveitis9.4%3 reports
  13. Weight gain9.4%3 reports
  14. Weight loss9.4%3 reports
  15. Allergy NOS[NOS: not otherwise specified]6.3%2 reports
  16. Anisocoria6.3%2 reports

The list shows 30 of 251 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)

Reports by species

The share is of all 32 reports that name dexamethasone + neomycin sulfate + polymyxin b sulfate. The other reports give a different species or no species.

Reports for each month, Jul 2021 to Jun 2026

Dog19 reports

No chart: no month has 5 or more reports.

Cat0 reports

No chart: no month has 5 or more reports.

Horse0 reports

No chart: no month has 5 or more reports.

Other or not given0 reports

No chart: no month has 5 or more reports.

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

  • Dog
  • Cat
  • Horse
  • Other or not given
Reports that name dexamethasone + neomycin sulfate + polymyxin b sulfate, by the year in which FDA received them and by species
YearDogCatHorseOther or not givenAll species
202620002
202550005
202460006
202360006
202111002
202010001
201921003
201840004
201710001
201610001
201410001

2026 has the reports that FDA received through Apr 2026. Download the years (CSV)

What the reports record

Outcome at the time of the report

  • Recovered/Normal15.6%5
  • Recovered with Sequela[recovered, with a lasting effect]3.1%1
  • Ongoing18.8%6
  • Died3.1%1
  • Euthanized6.3%2
  • Outcome Unknown53.1%17

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 32 reports that name dexamethasone + neomycin sulfate + polymyxin b sulfate.

A report about more than one animal can have more than one outcome.

Kind of report

  • Safety issue87.5%28
  • Lack of expected effectiveness6.3%2
  • Both safety and lack of expected effectiveness6.3%2
  • Manufacturing or product defect0%0
  • Other0%0

32 reports say if the event was serious. 78.1% of them have the serious flag. The person who sends the report sets the flag.

Show age, weight, breed and route

Age of the animal

  • Under 1 year25%8
  • 1 to 3 years9.4%3
  • 4 to 7 years25%8
  • 8 to 11 years18.8%6
  • 12 years and over18.8%6
  • Age not given3.1%1

Weight of the animal

  • Under 5 kg (11 lb)6.3%2
  • 5 to 9.9 kg (11 to 22 lb)46.9%15
  • 10 to 24.9 kg (22 to 55 lb)3.1%1
  • 25 to 44.9 kg (55 to 99 lb)25%8
  • 45 kg and over (99 lb and over)9.4%3
  • Weight not given9.4%3

Breed, where the report gives one breed

A breed with many animals has many reports.

Route in the report

  • Ophthalmic31.3%10
  • Intraocular3.1%1
  • Topical3.1%1

Each bar is on a scale of 0 to 100%.

Approved animal drugs with these active ingredients (FDA Green Book)

This section is reference data. It has no report count.

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

The Green Book lists no approved animal drug with these active ingredients. FDA also receives reports for human drugs and compounded drugs that veterinarians prescribe.

Other pages with one of these ingredients

A report names a drug by its set of active ingredients. Each set has its own page. The list is in order of name.

FDA pages for this drug

The site checked these addresses on . The links open in a new tab.

Cite this page

Pet Drug Reports. Dexamethasone + Neomycin Sulfate + Polymyxin B Sulfate: adverse event reports that FDA received. https://petdrugreports.com/drug/dexamethasone-neomycin-sulfate-polymyxin-b-sulfate/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book lists no brand name for exactly these active ingredients.

Do the reports show that the drug caused the signs?

No. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 7 reports in the 12 months to June 2026. It received 3 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 32 reports received from September 2014 to April 2026, 87.5% are about a safety issue only. 12.5% are about a lack of expected effectiveness, alone or with a safety issue.