Florfenicol (Nuflor, Nuflor-S): adverse event reports that FDA received
Active ingredient
Also sold as: Nuflor, Nuflor-S, NuflorGOLD, Loncor 300, Norfenicol, Florfeniject, and 4 more brand names.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
Read this first. FDA says this about the data:
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .
This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.
Contacting a veterinarianHow to report to FDAFrom January 1996 to June 2026, FDA received 1,082 adverse event reports that name a drug with florfenicol as its active ingredient. Of the 1,082 reports, 490 (45.3%) are about cattle. 183 reports are about people who were exposed to the drug (16.9%).
In January to March 2026, FDA received 4 reports that name this drug. The signs that appear in the largest number of the 1,082 reports are "Death", "Accidental exposure" and "Lack of efficacy (bacteria) - NOS". A report is not proof that a drug caused a sign.
Reports that name this drug fell by 5.5% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 1.9% of the reports that name this drug, and 72.6% of all reports.
Since the last update of the FDA data
The latest update of the FDA data, recorded on , changed no count of this page.
January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 4 reports that name florfenicol: 0 dog, 0 cat, 0 horse, 4 other or not given.
Signs that the reports list
A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 1,082 reports that list the sign. One report can list more than one sign.
The sign that is in the largest number of the reports comes first.
- Death32.3%350 reports
- Accidental exposure[exposure that was not intended]15.1%163 reports
- Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]14.7%159 reports
- Unclassifiable adverse event[event that fits no dictionary term]14.1%153 reports
- Lack of efficacy - NOS[the product did not have the expected effect]10.4%113 reports
- Injection site pain[pain where the injection was given]5.6%61 reports
- Diarrhoea[diarrhea]5.5%60 reports
- Anorexia[not eating]4.4%48 reports
- Injection site swelling[swelling where the injection was given]4.3%47 reports
- Anaphylaxis[sudden severe allergic-type reaction]4.3%46 reports
- Death by euthanasia[the animal was euthanized]4.3%46 reports
- No sign[no clinical sign was reported]3.3%36 reports
- Depression[dull, quiet or withdrawn]3.2%35 reports
- Containers, Damaged[a product quality report, not a sign in an animal]3%33 reports
Show the next 16 signs
- Recumbency[lying down and unable or unwilling to rise]3%32 reports
- Color, Abnormal[a product quality report, not a sign in an animal]2.8%30 reports
- Necropsy performed2.8%30 reports
- Collapse2.6%28 reports
- Vials, Leaking[a product quality report, not a sign in an animal]2.6%28 reports
- Ataxia[unsteady, uncoordinated movement]2.5%27 reports
- Respiratory tract disorder NOS[NOS: not otherwise specified]2.2%24 reports
- Respiratory signs2.1%23 reports
- Pneumonia[lung infection or inflammation]1.9%21 reports
- Solution, Abnormal[a product quality report, not a sign in an animal]1.9%21 reports
- Seal, Abnormal[a product quality report, not a sign in an animal]1.8%20 reports
- Found dead1.8%19 reports
- Injection site bleeding[bleeding where the injection was given]1.8%19 reports
- PR-lung(s), lesion(s)[legacy FDA term: lesions found in the lungs]1.8%19 reports
- Death-treatment failure1.6%17 reports
- Bronchopneumonia1.5%16 reports
The list shows 30 of 531 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)
Reports by species
The share is of all 1,082 reports that name florfenicol. The other reports give a different species or no species.
Reports for each month, Jul 2021 to Jun 2026
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Reports by year
- Dog
- Cat
- Horse
- Other or not given
| Year | Dog | Cat | Horse | Other or not given | All species |
|---|---|---|---|---|---|
| 2026 | 0 | 0 | 0 | 11 | 11 |
| 2025 | 3 | 5 | 0 | 57 | 65 |
| 2024 | 1 | 0 | 1 | 51 | 53 |
| 2023 | 2 | 0 | 0 | 33 | 35 |
| 2022 | 1 | 0 | 0 | 27 | 28 |
| 2021 | 0 | 0 | 0 | 25 | 25 |
| 2020 | 0 | 0 | 0 | 37 | 37 |
| 2019 | 3 | 1 | 0 | 24 | 28 |
| 2018 | 0 | 0 | 0 | 27 | 27 |
| 2017 | 0 | 0 | 0 | 25 | 25 |
| 2016 | 1 | 0 | 0 | 26 | 27 |
| 2015 | 0 | 1 | 0 | 34 | 35 |
| 2014 | 0 | 0 | 0 | 40 | 40 |
| 2013 | 0 | 0 | 0 | 64 | 64 |
| 2012 | 0 | 0 | 0 | 48 | 48 |
| 2011 | 0 | 0 | 0 | 24 | 24 |
| 2010 | 0 | 0 | 0 | 33 | 33 |
| 2009 | 0 | 0 | 0 | 22 | 22 |
| 2008 | 0 | 0 | 0 | 40 | 40 |
| 2007 | 3 | 0 | 0 | 33 | 36 |
| 2006 | 1 | 0 | 0 | 53 | 54 |
| 2005 | 0 | 0 | 0 | 29 | 29 |
| 2004 | 0 | 2 | 0 | 47 | 49 |
| 2003 | 2 | 0 | 0 | 24 | 26 |
| 2002 | 0 | 1 | 1 | 19 | 21 |
| 2001 | 0 | 1 | 1 | 22 | 24 |
| 2000 | 2 | 0 | 3 | 57 | 62 |
| 1999 | 0 | 0 | 1 | 21 | 22 |
| 1998 | 1 | 0 | 1 | 38 | 40 |
| 1997 | 1 | 0 | 2 | 25 | 28 |
| 1996 | 0 | 0 | 0 | 24 | 24 |
2026 has the reports that FDA received through Jun 2026. Download the years (CSV)
What the reports record
Outcome at the time of the report
- Recovered/Normal7.7%83
- Recovered with Sequela[recovered, with a lasting effect]0.3%3
- Ongoing6.8%74
- Died38.4%415
- Euthanized3.1%34
- Outcome Unknown9.2%100
An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 1,082 reports that name florfenicol.
A report about more than one animal can have more than one outcome.
Kind of report
- Safety issue65.2%706
- Lack of expected effectiveness11.6%125
- Both safety and lack of expected effectiveness3.6%39
- Manufacturing or product defect19.5%211
- Other0.1%1
310 reports say if the event was serious. 75.5% of them have the serious flag. The person who sends the report sets the flag.
Show age, weight, breed and route
Age of the animal
- Under 1 year28.4%307
- 1 to 3 years5.3%57
- 4 to 7 years1.6%17
- 8 to 11 years1.3%14
- 12 years and over14.9%161
- Age not given48.6%526
Weight of the animal
- Under 5 kg (11 lb)2.5%27
- 5 to 9.9 kg (11 to 22 lb)2%22
- 10 to 24.9 kg (22 to 55 lb)1.6%17
- 25 to 44.9 kg (55 to 99 lb)2%22
- 45 kg and over (99 lb and over)36.8%398
- Weight not given55.1%596
Breed, where the report gives one breed
- Holstein-Friesian7%76
- Aberdeen Angus3.7%40
- Cattle1%11
- Golden/Rainbow/Redband/Steelhead Trout0.9%10
- Limousin0.6%7
- Charolais0.6%6
- Hereford cattle0.5%5
- Brangus0.4%4
A breed with many animals has many reports.
Route in the report
- Subcutaneous23.3%252
- Intramuscular17%184
- Oral8.4%91
- Intradermal1.8%19
- Topical1.8%19
- Other1.1%12
Each bar is on a scale of 0 to 100%.
Approved animal drugs with this active ingredient (FDA Green Book)
This section is reference data. It has no report count.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
Brand names
- Nuflor
- Nuflor-S
- NuflorGOLD
- Loncor 300
- Norfenicol
- Florfeniject
- Aquaflor Type A Medicated Article
- Florvio 2.3%
- Florcon
- Paqflor
What the Green Book records give
- Applications with an approval in force
- 12
- Approved species
- Cattle, Swine, Fish
- Dose forms
- Injectable Solution, Liquid (Solution), Solution, Medicated Feed, Oral Concentrate Solution, Type A Medicated Article, Type A medicated articles to be used in the manufacture of Type C medicated feeds
- Routes
- Intramuscular, Oral, Subcutaneous
- Sale
- RX (prescription), VFD (veterinary feed directive)
- Earliest approval date in the records
The species, dose forms and routes are the words of the Green Book records for all the applications together. One product can have fewer. The label of a product gives its approved use.
| Brand name | Active ingredients | Sponsor | Approved species | Application |
|---|---|---|---|---|
| Nuflor; Nuflor-S | Florfenicol | Intervet, Inc. | Cattle, Swine | NADA 141-063 |
| Nuflor Concentrate Solution | Florfenicol | Intervet, Inc. | Swine | NADA 141-206 |
| Aquaflor Type A Medicated Article | Florfenicol | Intervet, Inc. | Not in the list of major species | NADA 141-246 |
| Nuflor | Florfenicol | Intervet, Inc. | Swine | NADA 141-264 |
| NuflorGOLD | Florfenicol | Intervet, Inc. | Cattle | NADA 141-265 |
| Florvio 2.3% Concentrate Solution | Florfenicol | Elanco US Inc. | Swine | ANADA 200-519 |
| Loncor 300 | Florfenicol | Zoetis Inc. | Cattle | ANADA 200-582 |
| Florfenicol Injection | Florfenicol | Sparhawk Laboratories, Inc. | Cattle | ANADA 200-588 |
| Florcon | Florfenicol | Bimeda Animal Health Ltd. | Swine | ANADA 200-589 |
| Norfenicol | Florfenicol | Norbrook Laboratories, Ltd. | Cattle | ANADA 200-591 |
| Florfeniject | Florfenicol | Cronus Pharma Specialities India Private Ltd. | Cattle | ANADA 200-760 |
| Paqflor | Florfenicol | Phibro Animal Health Corp. | Not in the list of major species | ANADA 200-803 |
Other pages with this ingredient
A report names a drug by its set of active ingredients. Each set has its own page. The list is in order of name.
Next in the A to Z list
FDA pages for this drug
- How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
- Green Book record of NADA 141-063The FDA record of the application for Nuflor, Nuflor-S.
- Green Book record of NADA 141-265The FDA record of the application for NuflorGOLD.
- Green Book record of ANADA 200-582The FDA record of the application for Loncor 300.
- Green Book record of ANADA 200-588The FDA record of the application for Florfenicol Injection.
- Green Book record of ANADA 200-591The FDA record of the application for Norfenicol.
- Green Book record of ANADA 200-760The FDA record of the application for Florfeniject.
- Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.
The site checked these addresses on . The links open in a new tab.
Cite this page
Pet Drug Reports. Florfenicol: adverse event reports that FDA received. https://petdrugreports.com/drug/florfenicol/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .
Where the data come from
The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.
The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.
Questions about these reports
- Which brand are these reports about?
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists the brand names with this active ingredient.
- Do the reports show that the drug caused the signs?
No. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
- How many reports did FDA receive in the latest 12 months?
FDA received 52 reports in the 12 months to June 2026. It received 55 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
- What kinds of report are in the count?
Of the 1,082 reports received from January 1996 to June 2026, 65.2% are about a safety issue only. 15.2% are about a lack of expected effectiveness, alone or with a safety issue. 19.5% are about a defect of the product or its package.