Citric Acid: adverse event reports that FDA received
Active ingredient
The Green Book lists no brand name for exactly this active ingredient.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
Read this first. FDA says this about the data:
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .
This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.
Contacting a veterinarianHow to report to FDAFrom August 2014 to December 2025, FDA received 20 adverse event reports that name a drug with citric acid as its active ingredient. Of the 20 reports, 15 (75%) are about dogs. 2 reports are about cats (10%).
In January to March 2026, FDA received no reports that name this drug. A report is not proof that a drug caused a sign.
Fewer than 20 reports named this drug in the 12 months before June 2026, so this page gives no change.
Search engines list a drug page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.
Since the last update of the FDA data
The latest update of the FDA data, recorded on , changed no count of this page.
January to March 2026 is the latest closed quarter in the data. In that quarter FDA received 0 reports that name citric acid: 0 dog, 0 cat, 0 horse, 0 other or not given.
Signs that the reports list
A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 20 reports that list the sign. One report can list more than one sign.
The sign that is in the largest number of the reports comes first.
- Diarrhoea[diarrhea]15%3 reports
- Seizure NOS[seizure, type not specified]15%3 reports
- Anaemia NOS[low red blood cell count]10%2 reports
- Anorexia[not eating]10%2 reports
- Death by euthanasia[the animal was euthanized]10%2 reports
- Distension of abdomen10%2 reports
- Extensor rigidity10%2 reports
- Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]10%2 reports
- Lack of efficacy - NOS[the product did not have the expected effect]10%2 reports
- Low platelet count10%2 reports
- Malodour10%2 reports
- Mass NOS[NOS: not otherwise specified]10%2 reports
- Pale mucous membrane[pale gums]10%2 reports
- Petit mal epilepsy10%2 reports
Show the next 16 signs
- Tense abdomen10%2 reports
- Urine leakage10%2 reports
- Vomiting10%2 reports
- Weakness10%2 reports
- Accidental exposure[exposure that was not intended]5%1 reports
- Allergic skin reaction5%1 reports
- Appearance, Abnormal[a product quality report, not a sign in an animal]5%1 reports
- Ataxia[unsteady, uncoordinated movement]5%1 reports
- Autoimmune disorder NOS[NOS: not otherwise specified]5%1 reports
- Behavioural disorder NOS[behaviour change, type not specified]5%1 reports
- Color, Abnormal[a product quality report, not a sign in an animal]5%1 reports
- Contamination, Foreign Object5%1 reports
- Decreased appetite5%1 reports
- Dermal mass5%1 reports
- Ear infection NOS[NOS: not otherwise specified]5%1 reports
- Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]5%1 reports
The list shows 30 of 66 coded signs. A report is not proof that a drug caused a sign. Download all signs (CSV)
Reports by species
The share is of all 20 reports that name citric acid. The other reports give a different species or no species.
Reports for each month, Jul 2021 to Jun 2026
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Reports by year
- Dog
- Cat
- Horse
- Other or not given
| Year | Dog | Cat | Horse | Other or not given | All species |
|---|---|---|---|---|---|
| 2025 | 1 | 0 | 0 | 1 | 2 |
| 2024 | 3 | 0 | 0 | 1 | 4 |
| 2023 | 2 | 0 | 0 | 1 | 3 |
| 2022 | 0 | 1 | 0 | 0 | 1 |
| 2021 | 2 | 0 | 0 | 0 | 2 |
| 2020 | 2 | 0 | 0 | 0 | 2 |
| 2019 | 1 | 0 | 0 | 0 | 1 |
| 2018 | 2 | 0 | 0 | 0 | 2 |
| 2015 | 1 | 1 | 0 | 0 | 2 |
| 2014 | 1 | 0 | 0 | 0 | 1 |
2025 has the reports that FDA received through Dec 2025. Download the years (CSV)
What the reports record
Outcome at the time of the report
- Recovered/Normal20%4
- Recovered with Sequela[recovered, with a lasting effect]0%0
- Ongoing15%3
- Died0%0
- Euthanized10%2
- Outcome Unknown45%9
An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 20 reports that name citric acid.
A report about more than one animal can have more than one outcome.
Kind of report
- Safety issue80%16
- Lack of expected effectiveness0%0
- Both safety and lack of expected effectiveness0%0
- Manufacturing or product defect20%4
- Other0%0
13 reports say if the event was serious. 61.5% of them have the serious flag. The person who sends the report sets the flag.
Show age, weight, breed and route
Age of the animal
- Under 1 year0%0
- 1 to 3 years10%2
- 4 to 7 years15%3
- 8 to 11 years35%7
- 12 years and over20%4
- Age not given20%4
Weight of the animal
- Under 5 kg (11 lb)15%3
- 5 to 9.9 kg (11 to 22 lb)10%2
- 10 to 24.9 kg (22 to 55 lb)35%7
- 25 to 44.9 kg (55 to 99 lb)15%3
- 45 kg and over (99 lb and over)5%1
- Weight not given20%4
Breed, where the report gives one breed
- Chihuahua15%3
- Domestic5%1
- Welsh Pembroke Corgi5%1
- Chesapeake Bay Retriever5%1
- Labrador Retriever5%1
- Shetland Sheepdog5%1
- Shih Tzu5%1
- Cavalier King Charles Spaniel5%1
A breed with many animals has many reports.
Route in the report
- Oral35%7
- Topical10%2
Each bar is on a scale of 0 to 100%.
Approved animal drugs with this active ingredient (FDA Green Book)
This section is reference data. It has no report count.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
No approved product has exactly this set of active ingredients. The ingredient field of a report can be incomplete. The approved products below have all the ingredients of this page and one or more other ingredients.
| Brand name | Active ingredients | Sponsor | Approved species | Application |
|---|---|---|---|---|
| Re-Sorb; Vytrate | Citric Acid, Dextrose, Glycine, Potassium Citrate, Potassium Phosphate, Sodium Chloride | Phibro Animal Health Corp. | Cattle | NADA 125-961 |
Other pages with this ingredient
A report names a drug by its set of active ingredients. Each set has its own page. The list is in order of name.
FDA pages for this drug
- How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
- Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.
The site checked these addresses on . The links open in a new tab.
Cite this page
Pet Drug Reports. Citric Acid: adverse event reports that FDA received. https://petdrugreports.com/drug/citric-acid/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .
Where the data come from
The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site does not use the application number that a record has.
The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.
Questions about these reports
- Which brand are these reports about?
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book lists no brand name for exactly this active ingredient.
- Do the reports show that the drug caused the signs?
No. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
- How many reports did FDA receive in the latest 12 months?
FDA received 1 report in the 12 months to June 2026. It received 3 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
- What kinds of report are in the count?
Of the 20 reports received from August 2014 to December 2025, 80% are about a safety issue only. 20% are about a defect of the product or its package.