Pet Drug Reports

Chihuahua: adverse event reports for animal drugs

Breed of dog

The FDA breed label is "Chihuahua". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From March 1987 to June 2026, FDA received 26,095 reports that give the breed Chihuahua. That is 2.6% of the reports about dogs. In the 12 months to June 2026, FDA received 1,052 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 26,095 reports are "Vomiting", "Lack of efficacy (ectoparasite) - flea" and "Lethargy". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 4 of 167 breeds of dogs with a page. Reports that give this breed fell by 3.2% in the 12 months to June 2026, compared with the 12 months before. Reports about dogs fell by 2.3% in the same periods. The newest months can get more reports in a later update. The sign "Lack of efficacy (ectoparasite) - flea" is in 11.7% of the reports that give this breed, and in 5.4% of the reports about dogs.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 178 drug pages.

Show the 178 drug pages
Drug pages with 5 or more reports that give the breed Chihuahua, in order of name
Active ingredientsReports that give this breed
(S) - methoprene229
Acepromazine Maleate52
Afoxolaner1,281
Afoxolaner + Moxidectin + Pyrantel Pamoate118
Alfaxalone27
Alprazolam13
Amantadine6
Amitraz49
Amoxicillin103
Amoxicillin + Clavulanate Potassium63
Amoxicillin Trihydrate + Clavulanate Potassium100
Ampicillin Sodium5
Ampicillin Trihydrate7
Atinvicitinib8
Atipamezole Hydrochloride48
Atropine24
Azithromycin5
Bacitracin8
Bedinvetmab300
Benazepril26
Benazepril hydrochloride + Spironolactone7
Betamethasone Acetate + Florfenicol + Terbinafine16
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate33
Betamethasone Valerate + Gentamicin Sulfate7
Bupivacaine10
Buprenorphine62
Butorphanol Tartrate132
Capromorelin52
Carprofen540
Cefovecin sodium249
Cefpodoxime proxetil45
Cephalexin30
Cetirizine8
Ciprofloxacin5
Clindamycin37
Clindamycin Hydrochloride9
Clomipramine Hydrochloride18
Clotrimazole + Gentamicin35
Clotrimazole + Gentamicin + Mometasone furoate5
Clotrimazole + Gentamicin Sulfate + Mometasone furoate6
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate29
Cyclosporine237
Deracoxib74
Desoxycorticosterone Pivalate49
Dexamethasone98
Dexamethasone + Neomycin Sulfate + Thiabendazole14
Dexamethasone + Thiabendazole11
Dexamethasone Sodium Phosphate20
Dexmedetomidine29
Dexmedetomidine hydrochloride95
Dextrose10
Diazepam29
Diphenhydramine174
Dirlotapide124
Doxycycline109
Doxycycline Hyclate6
Enalapril Maleate134
Enrofloxacin100
Enrofloxacin + Silver sulfadiazine8
Epsiprantel14
Estriol26
Etodolac6
Famotidine68
Febantel + Praziquantel + Pyrantel Pamoate246
Fenbendazole143
Fentanyl16
Firocoxib70
Florfenicol + Mometasone furoate + Terbinafine76
Florfenicol + Terbinafine50
Fluoxetine hydrochloride40
Fluralaner2,141
Furosemide187
Gabapentin167
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate27
Grapiprant112
Hydrocodone26
Hydrogen Peroxide8
Hydromorphone31
Hydroxyzine17
Ilunocitinib23
Imidacloprid229
Imidacloprid + Moxidectin615
Insulin276
Isoflurane86
Ivermectin314
Ivermectin + Praziquantel8
Ivermectin + Praziquantel + Pyrantel Pamoate356
Ivermectin + Pyrantel Pamoate2,196
Ketamine Hydrochloride51
Ketoconazole22
Ketoprofen9
Lactic Acid + Salicylic Acid12
Lactulose6
Levetiracetam18
Levothyroxine sodium53
Lidocaine5
Lotilaner202
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate53
Lufenuron17
Lufenuron + Milbemycin Oxime555
Lufenuron + Milbemycin Oxime + Praziquantel127
Lufenuron + Praziquantel91
Marbofloxacin30
Maropitant386
Medetomidine27
Melarsomine Dihydrochloride510
Melatonin6
Meloxicam490
Methocarbamol19
Methylprednisolone Acetate13
Metoclopramide9
Metronidazole63
Miconazole Nitrate7
Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate8
Midazolam44
Milbemycin Oxime490
Milbemycin Oxime + Praziquantel429
Milbemycin Oxime + Spinosad4,015
Minocycline6
Mirtazapine12
Moxidectin1,400
Moxidectin + Pyrantel Pamoate + Sarolaner14
Neomycin Sulfate + Nystatin7
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide16
Nitenpyram830
Nystatin + Thiostrepton + Triamcinolone Acetonide5
Oclacitinib537
Omeprazole8
Ondansetron8
Orbifloxacin18
Orbifloxacin + Posaconazole8
Ormetoprim + Sulfadimethoxine9
Pentobarbital Sodium + Phenytoin Sodium8
Phenobarbital67
Phenylpropanolamine hydrochloride7
Pimobendan519
Polysulfated Glycosaminoglycan51
Potassium bromide23
Potassium Citrate5
Praziquantel60
Praziquantel + Pyrantel Pamoate237
Prednisolone81
Prednisolone + Trimeprazine Tartrate75
Prednisone242
Propofol90
Pyrantel Pamoate205
Pyrantel Pamoate + Sarolaner809
Robenacoxib7
Ropinirole13
Salicylic Acid12
Sarolaner523
Sarolaner + Selamectin8
Selamectin880
Selegiline Hydrochloride42
Sevoflurane27
Sildenafil5
Silver sulfadiazine6
Sodium Chloride8
Spinosad3,150
Spironolactone15
Sucralfate19
Sulfadimethoxine34
Telmisartan6
Tepoxalin11
Theophylline19
Tigilanol tiglate69
Tiletamine Hydrochloride8
Tiletamine Hydrochloride + Zolazepam Hydrochloride15
Toceranib Phosphate13
Tramadol63
Trazodone24
Triamcinolone Acetonide17
Trilostane378
Tylosin Tartrate5
Ursodiol33
Verdinexor7
Vitamin E18
Zonisamide9

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 26,095 reports that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Vomiting21.9%5,709 reports
  2. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]11.7%3,061 reports
  3. Lethargy[unusually tired or inactive]11.3%2,957 reports
  4. Emesis[vomiting]8.2%2,131 reports
  5. Diarrhoea[diarrhea]7.3%1,896 reports
  6. Anorexia[not eating]5.6%1,472 reports
  7. Seizure NOS[seizure, type not specified]4.6%1,200 reports
  8. Depression[dull, quiet or withdrawn]4.5%1,169 reports
  9. Lack of efficacy - NOS[the product did not have the expected effect]4.3%1,121 reports
  10. Ataxia[unsteady, uncoordinated movement]3.7%954 reports
  11. Death3.3%866 reports
  12. Pruritus[itching]3.1%800 reports
  13. Shaking2.9%749 reports
  14. Behavioural disorder NOS[behaviour change, type not specified]2.7%712 reports
Show the next 11 signs
  1. Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]2.5%646 reports
  2. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]2.3%602 reports
  3. Overdose[more than the labelled amount was given]2.3%595 reports
  4. Accidental exposure[exposure that was not intended]2.3%590 reports
  5. Not eating2.2%587 reports
  6. Emesis (multiple)[vomiting more than once]2.2%582 reports
  7. Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]2.1%557 reports
  8. Trembling2.1%543 reports
  9. Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]1.8%482 reports
  10. Vocalisation[crying out or unusual noise]1.8%466 reports
  11. Lack of efficacy (flea)[the product did not have the expected effect: fleas]1.8%464 reports

What the reports record

Age of the animal

  • Chihuahua reports
  • All reports about dogs
  • Under 1 year10.6%2,771, All reports about dogs: 10.3%
  • 1 to 3 years27.3%7,129, All reports about dogs: 29.2%
  • 4 to 7 years25.7%6,694, All reports about dogs: 24.5%
  • 8 to 11 years19.3%5,035, All reports about dogs: 18.4%
  • 12 years and over12.1%3,164, All reports about dogs: 10.1%
  • Age not given5%1,302, All reports about dogs: 7.6%

Weight of the animal

  • Chihuahua reports
  • All reports about dogs
  • Under 5 kg (11 lb)71.7%18,699, All reports about dogs: 11.6%
  • 5 to 9.9 kg (11 to 22 lb)23.2%6,066, All reports about dogs: 18.7%
  • 10 to 24.9 kg (22 to 55 lb)1.2%324, All reports about dogs: 27.5%
  • 25 to 44.9 kg (55 to 99 lb)under 0.1%5, All reports about dogs: 30.4%
  • 45 kg and over (99 lb and over)under 0.1%7, All reports about dogs: 3.9%
  • Weight not given3.8%994, All reports about dogs: 7.9%

Outcome at the time of the report

  • Recovered/Normal29.1%7,581
  • Recovered with Sequela[recovered, with a lasting effect]3%776
  • Ongoing19%4,949
  • Died4%1,033
  • Euthanized1.3%339
  • Outcome Unknown25.3%6,598

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 26,095 reports that give this breed.

Each share of age and weight is of the 26,095 reports that give this breed. The thin bar is the same share in the 1,001,350 reports about dogs.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Chihuahua, by the year in which FDA received them
YearReports
2026514
20251,021
20241,156
2023927
2022991
20211,142
20201,284
20191,449
20181,530
20171,769
20161,692
20151,804
20141,750
20131,766
20121,717
20111,313
2010968
2009700
2008578
2007394
2006259
2005247
2004275
2003145
2002168
2001202
2000157
199961
199836
199716
199617
19959
19947
19931
19925
19913
19906
19895
19884
19877

Next in the A to Z list of breeds

All reports about dogs. All breeds

Cite this page

Pet Drug Reports. Chihuahua: adverse event reports for animal drugs. https://petdrugreports.com/breed/dog/chihuahua/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?

The figures are shares of the 26,095 reports about this breed received from March 1987 to June 2026. 27.3% give an age of 1 to 3 years. 25.7% give an age of 4 to 7 years. 5% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 1,052 reports in the 12 months to June 2026. It received 1,087 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Why are crossbred animals not in the count?

The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for dogs.

Do the reports show that this breed reacts more to a drug?

No. The reports do not give the number of animals of the breed. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices