Emesis: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: vomiting.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From September 2005 to June 2026, FDA received 69,533 adverse event reports for animal drugs that list this sign. That is 5% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 300 reports that list this sign.

Of the 69,533 reports, 91.6% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 4 of 1,149 clinical signs with a page. Reports that list this sign rose by 6.4% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 91.6% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 114 drug pages.

Show the 114 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
(S) - methoprene	136
Acepromazine Maleate	88
Afoxolaner	799
Alprazolam	47
Amitraz	35
Amoxicillin	102
Amoxicillin + Clavulanate Potassium	56
Amoxicillin Trihydrate + Clavulanate Potassium	200
Aspirin	21
Atipamezole Hydrochloride	37
Atropine	25
Bedinvetmab	54
Benazepril	24
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	48
Buprenorphine	90
Butorphanol Tartrate	81
Carprofen	976
Cefovecin sodium	252
Cefpodoxime proxetil	256
Cephalexin	371
Cetirizine	86
Ciprofloxacin	34
Clindamycin	73
Clomipramine Hydrochloride	41
Clotrimazole + Gentamicin	80
Cyclosporine	1,079
Deracoxib	257
Desoxycorticosterone Pivalate	40
Dexamethasone	147
Dexamethasone + Thiabendazole	33
Dexamethasone Sodium Phosphate	32
Dexmedetomidine hydrochloride	63
Diazepam	40
Diphenhydramine	435
Doxycycline	117
Emodepside + Praziquantel	99
Enalapril Maleate	87
Enrofloxacin	124
Epsiprantel	26
Famotidine	225
Febantel + Praziquantel + Pyrantel Pamoate	722
Fenbendazole	83
Fentanyl	35
Firocoxib	116
Florfenicol + Mometasone furoate + Terbinafine	54
Fluoxetine hydrochloride	101
Fluralaner	264
Frunevetmab	50
Furosemide	74
Gabapentin	103
Gentamicin Sulfate	22
Grapiprant	61
Hydrogen Peroxide	24
Hydromorphone	22
Hydroxyzine	231
Imidacloprid	184
Imidacloprid + Moxidectin	260
Insulin	99
Isoflurane	82
Ivermectin	1,474
Ivermectin + Praziquantel + Pyrantel Pamoate	105
Ivermectin + Pyrantel Pamoate	1,686
Ketamine Hydrochloride	40
Ketoconazole	147
Levothyroxine sodium	309
Lotilaner	156
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate	39
Lufenuron + Milbemycin Oxime	773
Lufenuron + Milbemycin Oxime + Praziquantel	26
Lufenuron + Praziquantel	127
Marbofloxacin	32
Maropitant	550
Melarsomine Dihydrochloride	105
Meloxicam	263
Methimazole	44
Methocarbamol	23
Metoclopramide	65
Metronidazole	245
Milbemycin Oxime	490
Milbemycin Oxime + Praziquantel	301
Milbemycin Oxime + Spinosad	41,538
Mirtazapine	31
Moxidectin	1,079
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide	20
Nitenpyram	235
Oclacitinib	327
Omeprazole	25
Pergolide mesylate	27
Phenobarbital	93
Phenylpropanolamine hydrochloride	21
Pimobendan	78
Polysulfated Glycosaminoglycan	117
Praziquantel	196
Praziquantel + Pyrantel Pamoate	220
Prednisolone	80
Prednisolone + Trimeprazine Tartrate	218
Prednisone	572
Propofol	54
Pyrantel Pamoate	229
Pyrantel Pamoate + Sarolaner	370
Rabacfosadine	25
Robenacoxib	60
Sarolaner	151
Selamectin	279
Spinosad	18,728
Sucralfate	86
Sulfadimethoxine	34
Tramadol	327
Trazodone	20
Triamcinolone	30
Triamcinolone Acetonide	42
Trilostane	28
Tylosin Tartrate	29
Vitamin E	52

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 112 ingredients.

Show the 112 ingredients

Reports by species

Dog91.6%63,696
Cat8.2%5,696
Human exposure0.1%41
Cattleunder 0.1%4
Other Canidsunder 0.1%4
Goatunder 0.1%3

The share is of the 69,533 reports that list this sign. The sign is in 6.4% of all reports about the species dog. The sign is in 3.8% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Emesis, by the year in which FDA received them
Year	Reports
2026	137
2025	297
2024	299
2023	330
2022	401
2021	506
2020	768
2019	954
2018	1,125
2017	1,659
2016	1,910
2015	8,155
2014	14,618
2013	18,820
2012	15,257
2011	4,249
2010	2
2008	41
2006	2
2005	3

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal85.3%59,281, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]2.7%1,911, All reports: 2.3%
Ongoing3.5%2,418, All reports: 17.4%
Died0.7%462, All reports: 4.9%
Euthanized0.7%500, All reports: 1.5%
Outcome Unknown7%4,889, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 69,533 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year16.4%11,383, All reports: 9.5%
1 to 3 years35.8%24,921, All reports: 23.9%
4 to 7 years25.2%17,547, All reports: 20.2%
8 to 11 years12.4%8,614, All reports: 15.4%
12 years and over5.3%3,685, All reports: 10.7%
Age not given4.9%3,383, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

Elevated thyroxine (T4)
Elevated total bilirubin[bilirubin above the normal range]
Elevated triglyceride
Embolism
Emesis (multiple)[vomiting more than once]
Enlarged liver
Enlarged lymph node (localised)
Enlarged lymph nodes (generalised)

All clinical signs

Cite this page

Pet Drug Reports. Emesis: adverse event reports for animal drugs. https://petdrugreports.com/reaction/emesis/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: In plain words: vomiting. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 300 reports in the 12 months to June 2026. It received 282 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 69,373 reports that say if the event was serious, 10% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices