Pet Drug Reports

Seizure NOS: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: seizure, type not specified.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From July 1999 to June 2026, FDA received 34,259 adverse event reports for animal drugs that list this sign. That is 2.5% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 2,784 reports that list this sign.

Of the 34,259 reports, 91.8% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 13 of 1,149 clinical signs with a page. Reports that list this sign fell by 15.2% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 91.8% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 136 drug pages.

Show the 136 drug pages
Drug pages with 20 or more reports that list this sign, in order of name
Active ingredientsReports that list the sign
(S) - methoprene269
Acepromazine Maleate110
Afoxolaner4,063
Afoxolaner + Moxidectin + Pyrantel Pamoate457
Alfaxalone52
Alprazolam30
Amantadine27
Amlodipine38
Amoxicillin91
Amoxicillin + Clavulanate Potassium100
Amoxicillin Trihydrate + Clavulanate Potassium118
Atipamezole Hydrochloride124
Atropine53
Bedinvetmab1,596
Benazepril28
Buprenorphine231
Butorphanol Tartrate326
Capromorelin54
Carprofen1,006
Cefovecin sodium605
Cefpodoxime proxetil220
Ceftiofur Crystalline Free Acid46
Cephalexin137
Cetirizine29
Clindamycin73
Clomipramine Hydrochloride27
Clotrimazole + Gentamicin20
Cyclosporine221
Deracoxib116
Desoxycorticosterone Pivalate21
Detomidine Hydrochloride25
Dexamethasone174
Dexamethasone + Neomycin Sulfate + Thiabendazole35
Dexamethasone Sodium Phosphate57
Dexmedetomidine121
Dexmedetomidine hydrochloride183
Dextrose47
Diazepam245
Diphenhydramine191
Doxycycline180
Emodepside + Praziquantel80
Enalapril Maleate125
Enrofloxacin312
Eprinomectin + Esafoxolaner + Praziquantel128
Estriol58
Famotidine130
Febantel + Praziquantel + Pyrantel Pamoate83
Fenbendazole49
Fentanyl21
Firocoxib168
Florfenicol + Mometasone furoate + Terbinafine105
Florfenicol + Terbinafine28
Flunixin Meglumine29
Fluoxetine hydrochloride145
Fluralaner3,394
Fluralaner + Moxidectin57
Frunevetmab192
Furosemide147
Gabapentin613
Grapiprant270
Hydrocodone33
Hydromorphone50
Hydroxyzine44
Ilunocitinib70
Imidacloprid242
Imidacloprid + Moxidectin559
Insulin356
Isoflurane171
Ivermectin484
Ivermectin + Praziquantel + Pyrantel Pamoate137
Ivermectin + Pyrantel Pamoate2,491
Ketamine Hydrochloride231
Ketoconazole69
Lactulose25
Levetiracetam343
Levothyroxine sodium184
Lotilaner682
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate131
Lufenuron + Milbemycin Oxime547
Lufenuron + Milbemycin Oxime + Praziquantel177
Lufenuron + Praziquantel86
Marbofloxacin54
Maropitant706
Melarsomine Dihydrochloride249
Meloxicam248
Methimazole48
Methocarbamol87
Methylprednisolone Acetate40
Metoclopramide41
Metronidazole154
Midazolam249
Milbemycin Oxime341
Milbemycin Oxime + Praziquantel871
Milbemycin Oxime + Spinosad4,209
Mirtazapine74
Moxidectin1,222
Moxidectin + Pyrantel Pamoate + Sarolaner78
Nitenpyram388
Oclacitinib1,155
Omeprazole45
Ondansetron33
Orbifloxacin34
Pergolide mesylate28
Phenobarbital627
Phenylpropanolamine hydrochloride33
Pimobendan239
Polysulfated Glycosaminoglycan136
Potassium bromide80
Praziquantel29
Praziquantel + Pyrantel Pamoate102
Prednisolone107
Prednisolone + Trimeprazine Tartrate68
Prednisone367
Propofol214
Pyrantel Pamoate158
Pyrantel Pamoate + Sarolaner4,373
Robenacoxib105
Sarolaner2,869
Sarolaner + Selamectin251
Selamectin808
Selegiline Hydrochloride31
Sevoflurane33
Sodium Chloride30
Spinosad1,297
Sucralfate49
Sulfadimethoxine23
Tiletamine Hydrochloride30
Tiletamine Hydrochloride + Zolazepam Hydrochloride22
Tramadol189
Trazodone109
Triamcinolone Acetonide23
Trilostane337
Ursodiol26
Vitamin E45
Xylazine37
Zonisamide120

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 132 ingredients.

Show the 132 ingredients

Reports by species

The share is of the 34,259 reports that list this sign. The sign is in 3.1% of all reports about the species dog. The sign is in 1.7% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Seizure NOS, by the year in which FDA received them
YearReports
20261,356
20253,075
20243,224
20232,464
20222,596
20212,395
20202,410
20192,561
20182,417
20172,143
20161,935
20151,958
20141,950
20131,804
20121,469
2011384
201021
20096
200845
20077
200614
20056
20041
200313
20024
19991

What these reports record

Outcome at the time of the report

  • Reports with this sign
  • All reports
  • Recovered/Normal37.1%12,701, All reports: 20.7%
  • Recovered with Sequela[recovered, with a lasting effect]1.8%615, All reports: 2.3%
  • Ongoing24.1%8,244, All reports: 17.4%
  • Died7.1%2,424, All reports: 4.9%
  • Euthanized7.8%2,656, All reports: 1.5%
  • Outcome Unknown22.5%7,701, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 34,259 reports that list this sign.

Age of the animal

  • Reports with this sign
  • All reports
  • Under 1 year8.4%2,890, All reports: 9.5%
  • 1 to 3 years22.3%7,652, All reports: 23.9%
  • 4 to 7 years26%8,891, All reports: 20.2%
  • 8 to 11 years20.3%6,957, All reports: 15.4%
  • 12 years and over17%5,813, All reports: 10.7%
  • Age not given6%2,056, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Seizure NOS: adverse event reports for animal drugs. https://petdrugreports.com/reaction/seizure-nos/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?

In plain words: seizure, type not specified. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 2,784 reports in the 12 months to June 2026. It received 3,284 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

How many of these reports have a serious flag?

Of the 33,855 reports that say if the event was serious, 86.3% have the serious flag. The person who sends a report sets the flag.

Does a drug in the table cause this sign?

The reports do not show that. A report can name more than one drug. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices