Pet Drug Reports

Vomiting: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From January 1987 to June 2026, FDA received 215,752 adverse event reports for animal drugs that list this sign. That is 15.7% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 7,871 reports that list this sign.

Of the 215,752 reports, 91% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 1 of 1,149 clinical signs with a page. Reports that list this sign fell by 8.3% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 91% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 232 drug pages.

Show the 232 drug pages
Drug pages with 20 or more reports that list this sign, in order of name
Active ingredientsReports that list the sign
(S) - methoprene1,140
Acepromazine Maleate314
Acetylsalicylic Acid54
Afoxolaner14,589
Afoxolaner + Moxidectin + Pyrantel Pamoate1,686
Albendazole45
Alfaxalone66
Alprazolam75
Amantadine61
Amitraz161
Amitraz + (S) - methoprene80
Amlodipine109
Amoxicillin1,204
Amoxicillin + Clavulanate Potassium395
Amoxicillin Trihydrate23
Amoxicillin Trihydrate + Clavulanate Potassium598
Ampicillin Sodium107
Ampicillin Trihydrate27
Apomorphine55
Aspirin49
Atenolol26
Atipamezole Hydrochloride326
Atropine153
Attapulgite31
Azithromycin25
Bacitracin52
Bedinvetmab1,610
Benazepril95
Benazepril hydrochloride20
Betamethasone Acetate + Florfenicol + Terbinafine51
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate75
Betamethasone Valerate + Gentamicin Sulfate30
Bexagliflozin452
Bismuth Subsalicylate26
Budesonide42
Bupivacaine42
Buprenorphine510
Butorphanol Tartrate685
Capromorelin375
Carprofen12,887
Cefadroxil37
Cefovecin sodium1,883
Cefpodoxime proxetil737
Ceftiofur Sodium21
Cephalexin762
Cetirizine106
Ciprofloxacin51
Cisapride25
Clindamycin190
Clindamycin Hydrochloride90
Clomipramine Hydrochloride310
Clotrimazole + Gentamicin67
Clotrimazole + Gentamicin + Mometasone furoate45
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate54
Cyclosporine5,193
Deracoxib3,419
Desoxycorticosterone Pivalate310
Dexamethasone842
Dexamethasone + Neomycin Sulfate + Thiabendazole104
Dexamethasone + Thiabendazole69
Dexamethasone Sodium Phosphate242
Dexmedetomidine213
Dexmedetomidine hydrochloride403
Dextrose79
Diazepam128
Dichlorophene + Toluene125
Diethylcarbamazine Citrate80
Diphenhydramine1,484
Dirlotapide927
Doramectin30
Doxycycline615
Emodepside + Praziquantel608
Enalapril Maleate259
Enrofloxacin911
Enrofloxacin + Silver sulfadiazine35
Eprinomectin29
Eprinomectin + Esafoxolaner + Praziquantel419
Eprinomectin + Praziquantel87
Epsiprantel106
Estriol114
Etodolac365
Famotidine894
Febantel + Praziquantel + Pyrantel Pamoate2,535
Fenbendazole1,167
Fentanyl93
Fenthion25
Firocoxib2,545
Florfenicol + Mometasone furoate + Terbinafine481
Florfenicol + Terbinafine110
Fluconazole58
Flunixin Meglumine26
Fluoxetine hydrochloride362
Fluralaner20,576
Fluralaner + Moxidectin130
Frunevetmab823
Furosemide299
Gabapentin1,649
Gentamicin28
Gentamicin Sulfate33
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate38
Glycopyrrolate28
Grapiprant1,472
Griseofulvin22
Hydrocodone58
Hydrocortisone20
Hydrogen Peroxide113
Hydromorphone179
Hydroxyzine177
Ilunocitinib237
Imepitoin29
Imidacloprid630
Imidacloprid + Moxidectin2,181
Imidocarb Dipropionate27
Insulin957
Isoflurane434
Itraconazole90
Ivermectin2,121
Ivermectin + Praziquantel44
Ivermectin + Praziquantel + Pyrantel Pamoate3,454
Ivermectin + Pyrantel Pamoate17,641
Ketamine Hydrochloride302
Ketoconazole284
Ketoprofen72
Lactic Acid + Salicylic Acid21
Lactulose51
Levetiracetam76
Levothyroxine sodium453
Lidocaine68
Loperamide24
Lotilaner2,858
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate861
Lufenuron526
Lufenuron + Milbemycin Oxime3,649
Lufenuron + Milbemycin Oxime + Praziquantel931
Lufenuron + Praziquantel580
Marbofloxacin293
Maropitant4,027
Mebendazole22
Meclofenamic Acid31
Medetomidine197
Medetomidine hydrochloride + Vatinoxan hydrochloride21
Melarsomine Dihydrochloride2,737
Melatonin41
Meloxicam3,107
Methadone37
Methimazole213
Methocarbamol132
Methylprednisolone38
Methylprednisolone Acetate290
Metoclopramide200
Metronidazole937
Midazolam249
Milbemycin Oxime3,910
Milbemycin Oxime + Praziquantel6,465
Milbemycin Oxime + Spinosad32,022
Minocycline20
Mirtazapine294
Misoprostol24
Molidustat87
Mometasone Furoate Monohydrate + Orbifloxacin + Posaconazole30
Moxidectin10,774
Moxidectin + Pyrantel Pamoate + Sarolaner164
Mupirocin21
Mycophenolate24
Neomycin Sulfate + Nystatin24
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide94
Nitenpyram1,483
Oclacitinib3,499
Omeprazole301
Ondansetron266
Orbifloxacin129
Orbifloxacin + Posaconazole21
Ormetoprim + Sulfadimethoxine125
Oxibendazole296
Oxytetracycline + Polymyxin B Sulfate43
Penicillin G Procaine27
Pergolide mesylate40
Phenobarbital170
Phenylpropanolamine hydrochloride173
Pimobendan955
Polysulfated Glycosaminoglycan1,081
Ponazuril24
Potassium bromide32
Potassium Citrate20
Pradofloxacin65
Praziquantel381
Praziquantel + Pyrantel Pamoate1,941
Prednisolone438
Prednisolone + Trimeprazine Tartrate264
Prednisone1,429
Propofol344
Pyrantel Pamoate1,317
Pyrantel Pamoate + Sarolaner9,367
Pyrantel Tartrate21
Rabacfosadine58
Robenacoxib300
Ropinirole37
Salicylic Acid32
Sarolaner3,850
Sarolaner + Selamectin626
Selamectin5,149
Selegiline Hydrochloride457
Sevoflurane114
Sodium Chloride69
Spinosad19,852
Spironolactone51
Sucralfate382
Sulfadimethoxine219
Telmisartan134
Tepoxalin276
Terbinafine27
Theophylline36
Tigilanol tiglate146
Tiletamine Hydrochloride48
Tiletamine Hydrochloride + Zolazepam Hydrochloride120
Tilmicosin Phosphate64
Toceranib Phosphate212
Tramadol826
Trazodone343
Triamcinolone45
Triamcinolone Acetonide176
Trilostane2,024
Trimethoprim25
Tylosin46
Tylosin Tartrate44
Ursodiol164
Velagliflozin690
Verdinexor115
Vincristine29
Vitamin E219
Xylazine28
Zonisamide44

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 217 ingredients.

Show the 217 ingredients

Reports by species

  • Dog91%196,271
  • Cat8.7%18,708
  • Human exposure0.2%494
  • Pigunder 0.1%82
  • Otherunder 0.1%45
  • Ferretunder 0.1%14

The share is of the 215,752 reports that list this sign. The sign is in 19.6% of all reports about the species dog. The sign is in 12.4% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Vomiting, by the year in which FDA received them
YearReports
20263,816
20258,228
20249,280
20238,667
20228,477
202110,281
202012,112
201913,097
201813,612
201715,963
201617,248
201512,986
20147,526
20136,768
20129,104
201110,481
20109,482
20095,977
20086,197
20073,957
20063,045
20053,023
20043,352
20032,065
20022,163
20011,906
20002,263
19991,396
19981,193
1997534
1996410
1995234
1994135
1993118
199290
199194
199067
1989107
1988130
1987168

What these reports record

Outcome at the time of the report

  • Reports with this sign
  • All reports
  • Recovered/Normal45.5%98,175, All reports: 20.7%
  • Recovered with Sequela[recovered, with a lasting effect]0.4%923, All reports: 2.3%
  • Ongoing10.3%22,256, All reports: 17.4%
  • Died4.8%10,379, All reports: 4.9%
  • Euthanized1.6%3,354, All reports: 1.5%
  • Outcome Unknown14%30,274, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 215,752 reports that list this sign.

Age of the animal

  • Reports with this sign
  • All reports
  • Under 1 year15.7%33,859, All reports: 9.5%
  • 1 to 3 years28.2%60,938, All reports: 23.9%
  • 4 to 7 years23.1%49,776, All reports: 20.2%
  • 8 to 11 years16.9%36,421, All reports: 15.4%
  • 12 years and over9.9%21,286, All reports: 10.7%
  • Age not given6.2%13,472, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Vomiting: adverse event reports for animal drugs. https://petdrugreports.com/reaction/vomiting/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?

It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 7,871 reports in the 12 months to June 2026. It received 8,585 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

How many of these reports have a serious flag?

Of the 155,987 reports that say if the event was serious, 33.5% have the serious flag. The person who sends a report sets the flag.

Does a drug in the table cause this sign?

The reports do not show that. A report can name more than one drug. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices