Praziquantel: adverse event reports in all combinations

Drug pages with praziquantel

A report names a drug by its set of active ingredients. Each set with praziquantel that has a drug page is in the table, in order of name. The table has 14 sets.

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 85,618 reports that list the sign. One report can list more than one sign and more than one drug.

The sign that is in the largest number of the reports comes first.

1. Vomiting21.2%18,153 reports
2. Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]11.9%10,193 reports
3. Lethargy[unusually tired or inactive]8.6%7,334 reports
4. Diarrhoea[diarrhea]7.8%6,668 reports
5. Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.8%4,955 reports
6. Ineffective, hooks[legacy FDA term: the product did not have the expected effect (hooks)]3.7%3,170 reports
7. Lack of efficacy (endoparasite) - tapeworm[the product did not have the expected effect: tapeworms]3.5%3,032 reports
8. Hypersalivation[drooling]2.9%2,490 reports
9. Ataxia[unsteady, uncoordinated movement]2.8%2,439 reports
10. Other abnormal test result NOS[abnormal laboratory result, type not specified]2.8%2,439 reports
11. Unpalatable[legacy FDA term: the animal would not take it]2.8%2,364 reports
12. Behavioural disorder NOS[behaviour change, type not specified]2.7%2,314 reports
13. Anorexia[not eating]2.7%2,271 reports
14. Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.6%2,187 reports

Download all signs (CSV)

Reports by species

• Dog74.4%63,693
• Cat14.7%12,555
• Horse3.5%3,016
• Human exposure0.4%322
• Donkeyunder 0.1%27
• Otherunder 0.1%8

Reports for each month, Jul 2021 to Jun 2026

The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports by year

• Dog
• Cat
• Horse
• Other or not given

2026 has the reports that FDA received through Jun 2026. Download the years (CSV)

What the reports record

Each share of kind and age is of the 85,618 reports that name praziquantel.

FDA pages for this ingredient

• How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
• Green Book record of NADA 111-607The FDA record of the application for Droncit 5.68% Injectible Solution.
• Green Book record of NADA 111-798The FDA record of the application for Droncit Canine Cestocide Tablets, Droncit Feline Cestocide Tablets, Praziquantel 34 (Rx), Tapeworm Dewormer for Cats (OTC), Tapeworm Dewormer for Dogs (OTC).
• Green Book record of NADA 133-953The FDA record of the application for Vercom Paste Anthelmintic.
• Green Book record of NADA 141-007The FDA record of the application for Drontal Plus, Drontal Plus Taste Tabs, Quad Dewormer.
• Green Book record of NADA 141-257The FDA record of the application for Iverhart MAX.
• Green Book record of NADA 141-261The FDA record of the application for Virbantel, Worm X Plus.
• Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Pet Drug Reports. Praziquantel, all combinations: adverse event reports that FDA received. https://petdrugreports.com/ingredient/praziquantel/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

Questions about these reports

Which brand are these reports about?

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists brand names with this active ingredient.

Do the reports show that the ingredient caused the signs?

No. A report can name more than one drug, and a drug can have more than one active ingredient. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

How many reports did FDA receive in the latest 12 months?

FDA received 7,903 reports in the 12 months to June 2026. It received 6,663 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 85,618 reports received from February 1987 to June 2026, 57.2% are about a safety issue only. 34.3% are about a lack of expected effectiveness, alone or with a safety issue. 8.4% are about a defect of the product or its package.