Pet Drug Reports

Cat: adverse event reports for animal drugs

Species

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From January 1987 to June 2026, FDA received 151,153 adverse event reports about cats for animal drugs. That is 11% of the 1,378,761 reports that FDA received from January 1987 to June 2026.

In the 12 months to June 2026, FDA received 12,213 reports about cats. The signs that appear in the largest number of the 151,153 reports are "Vomiting", "Lethargy" and "Lack of efficacy (ectoparasite) - flea". A report is not proof that a drug caused a sign.

Since the last update of the FDA data

The site recorded an update of the FDA data on . 77 drug pages with reports about cats have a different count. Open the update

All updatesFeed of updates (RSS)

Drug pages with reports about cats

The table has every drug page with 20 or more reports about cats, in order of name. No count decides which drug is in the table. The table has 181 drug pages.

Show the 181 drug pages
Drug pages with 20 or more reports about cats, in order of name
Active ingredientsReports about cats
(S) - methoprene459
Acepromazine Maleate601
Afoxolaner80
Alfaxalone471
Amlodipine378
Amoxicillin1,623
Amoxicillin + Amoxicillin Trihydrate + Clavulanate Potassium28
Amoxicillin + Clavulanate Potassium507
Amoxicillin Trihydrate48
Amoxicillin Trihydrate + Clavulanate Potassium776
Ampicillin Sodium78
Ampicillin Trihydrate73
Atenolol91
Atipamezole Hydrochloride1,037
Atropine245
Azithromycin86
Bacitracin107
Benazepril66
Betamethasone Acetate + Florfenicol + Terbinafine123
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate70
Betamethasone Valerate + Gentamicin Sulfate43
Bexagliflozin4,053
Budesonide110
Bupivacaine288
Buprenorphine5,599
Buprenorphine + Dexmedetomidine + Ketamine Hydrochloride30
Butorphanol Tartrate2,248
Butorphanol Tartrate + Dexmedetomidine + Ketamine Hydrochloride128
Capromorelin821
Carprofen1,711
Cefadroxil69
Cefovecin sodium8,685
Cefpodoxime proxetil87
Ceftiofur Sodium26
Cephalexin89
Cetirizine55
Chlorambucil73
Cisapride109
Clindamycin280
Clindamycin Hydrochloride206
Clomipramine Hydrochloride123
Clotrimazole + Gentamicin30
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate36
Cyclosporine3,029
Deracoxib101
Dexamethasone622
Dexamethasone + Neomycin Sulfate + Thiabendazole584
Dexamethasone + Thiabendazole221
Dexamethasone Sodium Phosphate169
Dexmedetomidine1,193
Dexmedetomidine + Ketamine Hydrochloride32
Dexmedetomidine hydrochloride1,434
Dextrose85
Diazepam265
Dichlorophene + Toluene193
Dimethyl Sulfoxide + Fluocinolone Acetonide21
Diphenhydramine368
Doramectin28
Doxycycline254
Emodepside + Praziquantel5,730
Enalapril Maleate109
Enrofloxacin1,557
Enrofloxacin + Silver sulfadiazine80
Eprinomectin22
Eprinomectin + Esafoxolaner + Praziquantel3,247
Eprinomectin + Praziquantel586
Epsiprantel224
Erythromycin46
Famotidine406
Febantel + Praziquantel + Pyrantel Pamoate70
Fenbendazole158
Fentanyl80
Firocoxib52
Florfenicol + Mometasone furoate + Terbinafine692
Florfenicol + Terbinafine138
Fluconazole27
Fluoxetine hydrochloride242
Fluralaner10,635
Fluralaner + Moxidectin3,239
Frunevetmab8,033
Furosemide304
Gabapentin1,953
Gentamicin20
Gentamicin Sulfate28
Glycopyrrolate78
Griseofulvin84
Hydrocortisone31
Hydrogen Peroxide27
Hydromorphone273
Imidacloprid1,532
Imidacloprid + Moxidectin8,157
Insulin3,682
Insulin Glargine67
Isoflurane2,036
Itraconazole443
Ivermectin998
Ivermectin + Pyrantel Pamoate66
Ketamine Hydrochloride3,750
Ketoconazole99
Ketoprofen86
Lactic Acid + Salicylic Acid36
Lactulose210
Levetiracetam38
Levothyroxine sodium29
Lidocaine175
Lotilaner901
Lufenuron1,108
Lufenuron + Milbemycin Oxime38
Marbofloxacin566
Maropitant3,847
Medetomidine465
Medetomidine hydrochloride26
Meloxicam3,653
Methadone110
Methimazole1,249
Methocarbamol40
Methylprednisolone143
Methylprednisolone Acetate1,491
Metoclopramide84
Metronidazole392
Miconazole Nitrate52
Midazolam748
Milbemycin Oxime406
Milbemycin Oxime + Spinosad300
Mirtazapine1,878
Molidustat613
Moxidectin47
Mupirocin54
Neomycin Sulfate + Nystatin24
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide158
Nitenpyram8,753
Nystatin + Thiostrepton + Triamcinolone22
Oclacitinib463
Omeprazole38
Ondansetron218
Orbifloxacin678
Ormetoprim + Sulfadimethoxine42
Oxibendazole28
Oxytetracycline35
Oxytetracycline + Polymyxin B Sulfate182
Pentobarbital109
Pentobarbital Sodium + Phenytoin Sodium108
Phenobarbital130
Pimobendan145
Piperonyl Butoxide + Pyrethrins21
Polysulfated Glycosaminoglycan316
Ponazuril48
Pradofloxacin524
Praziquantel1,686
Praziquantel + Pyrantel Pamoate1,260
Prednisolone1,235
Prednisone751
Pregabalin131
Propofol1,170
Pyrantel Pamoate559
Pyrantel Pamoate + Sarolaner50
Robenacoxib3,276
Salicylic Acid54
Sarolaner255
Sarolaner + Selamectin8,227
Selamectin22,042
Selegiline Hydrochloride39
Sevoflurane387
Silver sulfadiazine29
Sodium Chloride130
Spinosad11,584
Sucralfate92
Sulfadimethoxine322
Telmisartan422
Tiletamine Hydrochloride362
Tiletamine Hydrochloride + Zolazepam Hydrochloride1,575
Toceranib Phosphate99
Tramadol35
Trazodone20
Triamcinolone67
Triamcinolone Acetonide89
Tylosin39
Ursodiol48
Velagliflozin4,798
Vitamin E34
Xylazine167

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Download all drugs for this species (CSV)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 151,153 reports about cats that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Vomiting12.4%18,708 reports
  2. Lethargy[unusually tired or inactive]9.7%14,661 reports
  3. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]7.6%11,414 reports
  4. Anorexia[not eating]7.2%10,926 reports
  5. Application site alopecia[hair loss where the product was applied]6.1%9,247 reports
  6. Death5.4%8,151 reports
  7. Application site hair loss[hair loss where the product was applied]5.3%8,021 reports
  8. Lack of efficacy - NOS[the product did not have the expected effect]4.8%7,288 reports
  9. Diarrhoea[diarrhea]4.8%7,243 reports
  10. Behavioural disorder NOS[behaviour change, type not specified]4.5%6,877 reports
  11. Weight loss4.5%6,828 reports
  12. Ataxia[unsteady, uncoordinated movement]4.4%6,670 reports
  13. Hypersalivation[drooling]4.1%6,186 reports
  14. Depression[dull, quiet or withdrawn]4.1%6,135 reports
Show the next 16 signs
  1. Emesis[vomiting]3.8%5,696 reports
  2. Death by euthanasia[the animal was euthanized]3.6%5,441 reports
  3. Hyperactivity3.1%4,642 reports
  4. Not eating3%4,595 reports
  5. Vocalisation[crying out or unusual noise]2.9%4,366 reports
  6. Fever2.7%4,066 reports
  7. Accidental exposure[exposure that was not intended]2.6%3,918 reports
  8. Pruritus[itching]2.5%3,799 reports
  9. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]2.5%3,718 reports
  10. Hiding2.4%3,570 reports
  11. Decreased appetite2.3%3,486 reports
  12. Ketosis[ketones building up in the body]2.1%3,248 reports
  13. Elevated creatinine[a kidney value above the normal range]2.1%3,110 reports
  14. Dehydration2%2,993 reports
  15. Hyperglycaemia[high blood sugar]1.9%2,901 reports
  16. Panting1.9%2,841 reports

Download all signs (CSV)

Reports by month and by year

Reports about cats for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports about cats, by the year in which FDA received them
YearReports
20265,688
202512,659
202414,440
202310,917
20226,414
20216,171
20206,731
20197,382
20187,222
20177,391
20166,419
20156,154
20146,067
20136,717
20125,547
20114,150
20104,429
20094,142
20083,220
20072,563
20062,015
20051,592
20041,529
20031,200
20021,536
20012,198
20002,429
1999926
1998714
1997463
1996471
1995362
1994252
1993251
1992186
1991197
1990130
1989135
198889
198755

What the reports record

Age of the animal

  • Under 1 year12.1%18,354
  • 1 to 3 years19.7%29,837
  • 4 to 7 years18.3%27,660
  • 8 to 11 years17%25,770
  • 12 years and over20%30,258
  • Age not given12.8%19,274

Weight of the animal

  • Under 5 kg (11 lb)50.3%76,082
  • 5 to 9.9 kg (11 to 22 lb)34.1%51,499
  • 10 to 24.9 kg (22 to 55 lb)0.5%808
  • 25 to 44.9 kg (55 to 99 lb)under 0.1%12
  • 45 kg and over (99 lb and over)under 0.1%24
  • Weight not given15%22,728

Outcome at the time of the report

  • Reports about cats
  • All reports
  • Recovered/Normal20.3%30,758, All reports: 20.7%
  • Recovered with Sequela[recovered, with a lasting effect]0.5%738, All reports: 2.3%
  • Ongoing23.8%36,005, All reports: 17.4%
  • Died6.8%10,344, All reports: 4.9%
  • Euthanized2.6%3,961, All reports: 1.5%
  • Outcome Unknown26.4%39,855, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 151,153 reports about cats.

Kind of report

  • Reports about cats
  • All reports
  • Safety issue83.9%126,789, All reports: 64.5%
  • Lack of expected effectiveness8.7%13,158, All reports: 18.9%
  • Both safety and lack of expected effectiveness5.3%7,992, All reports: 4.3%
  • Manufacturing or product defect2%3,057, All reports: 12.2%
  • Other0.1%157, All reports: 0.1%

Each share of age, weight and kind is of the 151,153 reports about cats. The thin bar is the same share in all 1,378,761 reports.

Ingredients, all combinations

The list has every active ingredient with 20 or more reports about cats, in order of name. It has 175 ingredients.

Show the 175 ingredients

Breeds with a page

A breed has a page when 100 or more reports give that one breed. Reports about crossbred animals are in the species count only.

Cite this page

Pet Drug Reports. Cat: adverse event reports for animal drugs. https://petdrugreports.com/species/cat/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

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Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the cats in the reports?

The figures are shares of the 151,153 reports about cats received from January 1987 to June 2026. 20% give an age of 12 years and over. 19.7% give an age of 1 to 3 years. 12.8% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 12,213 reports in the 12 months to June 2026. It received 13,649 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 151,153 reports received from January 1987 to June 2026, 83.9% are about a safety issue only. 14% are about a lack of expected effectiveness, alone or with a safety issue. 2% are about a defect of the product or its package.

Do more reports for cats show a higher risk for cats?

No. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices