Cat: adverse event reports for animal drugs
Species
Read this first. FDA says this about the data:
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .
This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.
Contacting a veterinarianHow to report to FDAFrom January 1987 to June 2026, FDA received 151,153 adverse event reports about cats for animal drugs. That is 11% of the 1,378,761 reports that FDA received from January 1987 to June 2026.
In the 12 months to June 2026, FDA received 12,213 reports about cats. The signs that appear in the largest number of the 151,153 reports are "Vomiting", "Lethargy" and "Lack of efficacy (ectoparasite) - flea". A report is not proof that a drug caused a sign.
Since the last update of the FDA data
The site recorded an update of the FDA data on . 77 drug pages with reports about cats have a different count. Open the update
Drug pages with reports about cats
The table has every drug page with 20 or more reports about cats, in order of name. No count decides which drug is in the table. The table has 181 drug pages.
Show the 181 drug pages
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
Signs that the reports list
A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 151,153 reports about cats that list the sign.
The sign that is in the largest number of the reports comes first.
- Vomiting12.4%18,708 reports
- Lethargy[unusually tired or inactive]9.7%14,661 reports
- Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]7.6%11,414 reports
- Anorexia[not eating]7.2%10,926 reports
- Application site alopecia[hair loss where the product was applied]6.1%9,247 reports
- Death5.4%8,151 reports
- Application site hair loss[hair loss where the product was applied]5.3%8,021 reports
- Lack of efficacy - NOS[the product did not have the expected effect]4.8%7,288 reports
- Diarrhoea[diarrhea]4.8%7,243 reports
- Behavioural disorder NOS[behaviour change, type not specified]4.5%6,877 reports
- Weight loss4.5%6,828 reports
- Ataxia[unsteady, uncoordinated movement]4.4%6,670 reports
- Hypersalivation[drooling]4.1%6,186 reports
- Depression[dull, quiet or withdrawn]4.1%6,135 reports
Show the next 16 signs
- Emesis[vomiting]3.8%5,696 reports
- Death by euthanasia[the animal was euthanized]3.6%5,441 reports
- Hyperactivity3.1%4,642 reports
- Not eating3%4,595 reports
- Vocalisation[crying out or unusual noise]2.9%4,366 reports
- Fever2.7%4,066 reports
- Accidental exposure[exposure that was not intended]2.6%3,918 reports
- Pruritus[itching]2.5%3,799 reports
- Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]2.5%3,718 reports
- Hiding2.4%3,570 reports
- Decreased appetite2.3%3,486 reports
- Ketosis[ketones building up in the body]2.1%3,248 reports
- Elevated creatinine[a kidney value above the normal range]2.1%3,110 reports
- Dehydration2%2,993 reports
- Hyperglycaemia[high blood sugar]1.9%2,901 reports
- Panting1.9%2,841 reports
Reports by month and by year
FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
| Year | Reports |
|---|---|
| 2026 | 5,688 |
| 2025 | 12,659 |
| 2024 | 14,440 |
| 2023 | 10,917 |
| 2022 | 6,414 |
| 2021 | 6,171 |
| 2020 | 6,731 |
| 2019 | 7,382 |
| 2018 | 7,222 |
| 2017 | 7,391 |
| 2016 | 6,419 |
| 2015 | 6,154 |
| 2014 | 6,067 |
| 2013 | 6,717 |
| 2012 | 5,547 |
| 2011 | 4,150 |
| 2010 | 4,429 |
| 2009 | 4,142 |
| 2008 | 3,220 |
| 2007 | 2,563 |
| 2006 | 2,015 |
| 2005 | 1,592 |
| 2004 | 1,529 |
| 2003 | 1,200 |
| 2002 | 1,536 |
| 2001 | 2,198 |
| 2000 | 2,429 |
| 1999 | 926 |
| 1998 | 714 |
| 1997 | 463 |
| 1996 | 471 |
| 1995 | 362 |
| 1994 | 252 |
| 1993 | 251 |
| 1992 | 186 |
| 1991 | 197 |
| 1990 | 130 |
| 1989 | 135 |
| 1988 | 89 |
| 1987 | 55 |
What the reports record
Age of the animal
- Under 1 year12.1%18,354
- 1 to 3 years19.7%29,837
- 4 to 7 years18.3%27,660
- 8 to 11 years17%25,770
- 12 years and over20%30,258
- Age not given12.8%19,274
Weight of the animal
- Under 5 kg (11 lb)50.3%76,082
- 5 to 9.9 kg (11 to 22 lb)34.1%51,499
- 10 to 24.9 kg (22 to 55 lb)0.5%808
- 25 to 44.9 kg (55 to 99 lb)under 0.1%12
- 45 kg and over (99 lb and over)under 0.1%24
- Weight not given15%22,728
Outcome at the time of the report
- Reports about cats
- All reports
- Recovered/Normal20.3%30,758, All reports: 20.7%
- Recovered with Sequela[recovered, with a lasting effect]0.5%738, All reports: 2.3%
- Ongoing23.8%36,005, All reports: 17.4%
- Died6.8%10,344, All reports: 4.9%
- Euthanized2.6%3,961, All reports: 1.5%
- Outcome Unknown26.4%39,855, All reports: 22.7%
An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 151,153 reports about cats.
Kind of report
- Reports about cats
- All reports
- Safety issue83.9%126,789, All reports: 64.5%
- Lack of expected effectiveness8.7%13,158, All reports: 18.9%
- Both safety and lack of expected effectiveness5.3%7,992, All reports: 4.3%
- Manufacturing or product defect2%3,057, All reports: 12.2%
- Other0.1%157, All reports: 0.1%
Each share of age, weight and kind is of the 151,153 reports about cats. The thin bar is the same share in all 1,378,761 reports.
Ingredients, all combinations
The list has every active ingredient with 20 or more reports about cats, in order of name. It has 175 ingredients.
Show the 175 ingredients
- (S) - methoprene
- Acepromazine Maleate
- Afoxolaner
- Alfaxalone
- Amlodipine
- Amoxicillin
- Amoxicillin Trihydrate
- Ampicillin Sodium
- Ampicillin Trihydrate
- Atenolol
- Atipamezole Hydrochloride
- Atropine
- Azithromycin
- Bacitracin
- Benazepril
- Betamethasone Acetate
- Betamethasone Valerate
- Bexagliflozin
- Budesonide
- Bupivacaine
- Buprenorphine
- Butorphanol Tartrate
- Capromorelin
- Carprofen
- Cefadroxil
- Cefovecin sodium
- Cefpodoxime proxetil
- Ceftiofur Sodium
- Cephalexin
- Cetirizine
- Chlorambucil
- Chloramphenicol
- Cisapride
- Clavulanate Potassium
- Clindamycin
- Clindamycin Hydrochloride
- Clomipramine Hydrochloride
- Clotrimazole
- Cyclosporine
- Deracoxib
- Dexamethasone
- Dexamethasone Sodium Phosphate
- Dexmedetomidine
- Dexmedetomidine hydrochloride
- Dextrose
- Diazepam
- Dichlorophene
- Dimethyl Sulfoxide
- Diphenhydramine
- Doramectin
- Doxycycline
- Emodepside
- Enalapril Maleate
- Enrofloxacin
- Eprinomectin
- Epsiprantel
- Erythromycin
- Esafoxolaner
- Famotidine
- Febantel
- Fenbendazole
- Fentanyl
- Firocoxib
- Florfenicol
- Fluconazole
- Fluocinolone Acetonide
- Fluoxetine hydrochloride
- Fluralaner
- Frunevetmab
- Furosemide
- Gabapentin
- Gentamicin
- Gentamicin Sulfate
- Glycopyrrolate
- Griseofulvin
- Hydrocortisone
- Hydrogen Peroxide
- Hydromorphone
- Imidacloprid
- Insulin
- Insulin Glargine
- Isoflurane
- Itraconazole
- Ivermectin
- Ketamine Hydrochloride
- Ketoconazole
- Ketoprofen
- Lactic Acid
- Lactulose
- Levetiracetam
- Levothyroxine sodium
- Lidocaine
- Lotilaner
- Lufenuron
- Marbofloxacin
- Maropitant
- Medetomidine
- Medetomidine hydrochloride
- Meloxicam
- Methadone
- Methimazole
- Methocarbamol
- Methylprednisolone
- Methylprednisolone Acetate
- Metoclopramide
- Metronidazole
- Miconazole Nitrate
- Midazolam
- Milbemycin Oxime
- Mirtazapine
- Molidustat
- Mometasone furoate
- Mometasone Furoate Monohydrate
- Moxidectin
- Mupirocin
- Neomycin Sulfate
- Nitenpyram
- Nystatin
- Oclacitinib
- Omeprazole
- Ondansetron
- Orbifloxacin
- Ormetoprim
- Oxibendazole
- Oxytetracycline
- Penicillin G Benzathine
- Penicillin G Procaine
- Pentobarbital
- Pentobarbital Sodium
- Phenobarbital
- Phenytoin Sodium
- Pimobendan
- Piperonyl Butoxide
- Polymyxin B Sulfate
- Polysulfated Glycosaminoglycan
- Ponazuril
- Posaconazole
- Pradofloxacin
- Praziquantel
- Prednisolone
- Prednisolone Acetate
- Prednisone
- Pregabalin
- Propofol
- Pyrantel Pamoate
- Pyrethrins
- Robenacoxib
- Salicylic Acid
- Sarolaner
- Selamectin
- Selegiline Hydrochloride
- Sevoflurane
- Silver sulfadiazine
- Sodium Chloride
- Spinosad
- Spironolactone
- Sucralfate
- Sulfadimethoxine
- Telmisartan
- Terbinafine
- Thiabendazole
- Thiostrepton
- Tiletamine Hydrochloride
- Toceranib Phosphate
- Toluene
- Tramadol
- Trazodone
- Triamcinolone
- Triamcinolone Acetonide
- Tylosin
- Ursodiol
- Velagliflozin
- Vitamin E
- Xylazine
- Zolazepam Hydrochloride
Breeds with a page
- Abyssinian cat
- American Curl Shorthair
- American Shorthair
- Bengal
- Bombay
- British cat
- Burmese
- Domestic Longhair
- Domestic Mediumhair
- Domestic Shorthair
- Himalayan
- Maine Coon
- Manx
- Norwegian Forest
- Persian
- Ragdoll
- Russian
- Siamese
- Siberian
- Sphynx
- Tonkinese
A breed has a page when 100 or more reports give that one breed. Reports about crossbred animals are in the species count only.
Cite this page
Pet Drug Reports. Cat: adverse event reports for animal drugs. https://petdrugreports.com/species/cat/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .
Where the data come from
The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026.
The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.
Questions about these reports
- What ages are the cats in the reports?
The figures are shares of the 151,153 reports about cats received from January 1987 to June 2026. 20% give an age of 12 years and over. 19.7% give an age of 1 to 3 years. 12.8% give no age.
- How does the count of the latest 12 months compare with the 12 months before?
FDA received 12,213 reports in the 12 months to June 2026. It received 13,649 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
- What kinds of report are in the count?
Of the 151,153 reports received from January 1987 to June 2026, 83.9% are about a safety issue only. 14% are about a lack of expected effectiveness, alone or with a safety issue. 2% are about a defect of the product or its package.
- Do more reports for cats show a higher risk for cats?
No. FDA states this about the data.
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices