Species
Pig: adverse event reports
2,615 reports, 0.2% of FDA's animal drug adverse event database
2,615 adverse event reports in FDA's database concern pigs: 0.2% of all reports received from January 1987 to March 2026. 55 arrived in the 12 months to March 2026, close to the 56 of the 12 months before. That is 0.1% of all reports received in those 12 months and about 67 reports a year over the whole record.
By active ingredient, the drugs named most often are tylosin (7.8% of pig reports), narasin (6.5% of pig reports), tilmicosin phosphate (5.7% of pig reports) and ivermectin (5.5% of pig reports). Drugs given to the most animals lead the list for that reason; brands are masked in the public data.
The terms listed most often are death (38.3%), lack of efficacy (bacteria) - NOS (8.3%) and recumbency (7.7%). 60.3% of reports stating seriousness were classed as serious (38.6% across all species), and 49.1% record a death or euthanasia (6.4% overall).
FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.
Drugs named most often, by active ingredient
| Active ingredients recorded for the drug | Reports | Share of pig reports | Share of the drug's reports that concern pigs |
|---|---|---|---|
| Tylosin | 204 | 7.8% | 17.2% |
| Narasin | 170 | 6.5% | 39.3% |
| Tilmicosin Phosphate | 150 | 5.7% | 4.2% |
| Ivermectin | 143 | 5.5% | 0.7% |
| Doramectin | 142 | 5.4% | 3% |
| Ractopamine Hydrochloride | 104 | 4% | 31.9% |
| Tiamulin | 90 | 3.4% | 70.3% |
| Dextran | 87 | 3.3% | 75% |
| Tulathromycin | 79 | 3% | 2.5% |
| Tiamulin Hydrogen Fumarate | 71 | 2.7% | 67% |
| Enrofloxacin | 53 | 2% | 0.7% |
| Lincomycin Hydrochloride | 49 | 1.9% | 36.3% |
| Monensin | 49 | 1.9% | 1% |
| Penicillin G Procaine | 49 | 1.9% | 6.7% |
| Fenbendazole | 35 | 1.3% | 0.8% |
| Ceftiofur Crystalline Free Acid | 33 | 1.3% | 1.5% |
| Florfenicol | 33 | 1.3% | 3.1% |
| Chlortetracycline | 32 | 1.2% | 25.6% |
| Tilmicosin | 32 | 1.2% | 6.4% |
| Tylosin Phosphate | 32 | 1.2% | 14.1% |
| Altrenogest | 31 | 1.2% | 6.4% |
| Penicillin G Benzathine + Penicillin G Procaine | 25 | 1% | 8.1% |
| Dinoprost Tromethamine | 22 | 0.8% | 1.7% |
| Oxytetracycline | 19 | 0.7% | 1.5% |
| Avilamycin | 18 | 0.7% | 31.6% |
| Carbadox | 18 | 0.7% | 69.2% |
| Flunixin Meglumine | 18 | 0.7% | 1.2% |
| Ketamine Hydrochloride | 18 | 0.7% | 0.3% |
| Vitamin E | 18 | 0.7% | 1.5% |
| Dichlorvos | 17 | 0.7% | 40.5% |
Ordered by report count, which follows how widely a drug is used. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another". openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.
Signs listed in reports
share of pig reports listing the termall species
- Death38.3%1,001
- Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]8.3%218
- Recumbency[lying down and unable or unwilling to rise]7.7%201
- Lack of efficacy - NOS[the product did not have the expected effect]7.2%187
- Diarrhoea[diarrhea]5.2%137
- Lameness5.1%133
- Death by euthanasia[the animal was euthanized]4.8%125
- Anaphylaxis[sudden severe allergic-type reaction]4.7%124
- Anorexia[not eating]4.5%118
- Lack of efficacy (ectoparasite) - mite NOS[the product did not have the expected effect: mite NOS]4%104
- Depression[dull, quiet or withdrawn]3.2%84
- Vomiting3.1%82
- Dyspnoea[difficulty breathing]2.9%75
- Ataxia[unsteady, uncoordinated movement]2.6%69
- Accidental exposure[exposure that was not intended]2.4%64
- Lethargy[unusually tired or inactive]2.2%57
- Vocalisation[crying out or unusual noise]2.1%54
- Hyperactivity2%52
- Behavioural disorder NOS[behaviour change, type not specified]2%51
- Trembling1.8%47
- No sign[no clinical sign was reported]1.7%45
- Abortion1.7%44
- Convulsion[seizure]1.5%39
- Reluctant to move1.5%39
- Death-treatment failure1.4%37
- Loose stool1.4%36
- Pruritus[itching]1.4%36
- Rectal prolapse1.4%36
- Shaking1.4%36
- Skin hyperaemia[reddened skin]1.4%36
Single ingredients, pooled across combinations
- Tylosin209 reports · 8%
- Narasin170 reports · 6.5%
- Tilmicosin Phosphate150 reports · 5.7%
- Ivermectin144 reports · 5.5%
- Doramectin143 reports · 5.5%
- Ractopamine Hydrochloride104 reports · 4%
- Tiamulin90 reports · 3.4%
- Dextran87 reports · 3.3%
- Tulathromycin79 reports · 3%
- Penicillin G Procaine74 reports · 2.8%
- Tiamulin Hydrogen Fumarate71 reports · 2.7%
- Enrofloxacin53 reports · 2%
- Monensin50 reports · 1.9%
- Lincomycin Hydrochloride49 reports · 1.9%
- Fenbendazole35 reports · 1.3%
- Florfenicol34 reports · 1.3%
Age and weight
Age of the animal
Weight of the animal
Outcomes and report types
Outcome recorded in the report
What kind of report it was
Coloured bar: pig reports. Grey bar: all 1,357,245 reports. Outcomes are as stated by the reporter.
Trend
Reports by month FDA received them. The newest months are incomplete because FDA posts reports with a delay of three to six months.
| Measure | Pig | All reports |
|---|---|---|
| Reports | 2,615 | 1,357,245 |
| Classed serious, of reports stating it | 60.3% | 38.6% |
| Death or euthanasia recorded, per 1,000 reports | 491 | 63.8 |
| Filed as lack of expected effectiveness (wholly or partly) | 7.4% | 23% |
Questions about pig reports
How many adverse event reports involve pigs?
2,615 reports through March 2026, 0.2% of the database; 55 in the latest 12 months.
Which drugs are reported most often for pigs?
By active ingredient: tylosin (204), narasin (170), tilmicosin phosphate (150), ivermectin (143) and doramectin (142). The order tracks how widely each is used; brands are masked in the public data.
What signs are reported most in pigs?
death (38.3%), lack of efficacy (bacteria) - NOS (8.3%), recumbency (7.7%), lack of efficacy - NOS (7.2%) and diarrhoea (5.2%).
What ages are the pigs in these reports?
under 1 year (43%), 1 to 3 years (3.6%) and 4 to 7 years (0.3%); age is not given in 52.6% of reports.
Do more reports mean more risk for this species?
No. Counts follow how many animals are treated and how readily their owners and veterinarians report. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."
How do I report a problem?
Call the drug company using the number on the label, or send Form FDA 1932a to FDA. See the guide on how to report.
Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.