Ingredients

Ingredient sets that include sulfadimethoxine

Ordered by report count. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another"; counts follow sales volume and years on the market. A report can list more than one set, so shares can add to more than 100%.

Signs listed in reports, pooled

share of sulfadimethoxine reports listing the termall reports in the database

1. Vomiting11.8%333
2. Lack of efficacy (protozoa) - Coccidia[the product did not have the expected effect: coccidia]10.8%306
3. Depression[dull, quiet or withdrawn]9.7%273
4. Anorexia[not eating]8.1%229
5. Death7.7%218
6. Diarrhoea[diarrhea]7.4%209
7. Fever7%197
8. Ataxia[unsteady, uncoordinated movement]6.1%171
9. Lethargy[unusually tired or inactive]5.2%147
10. Anaemia NOS[low red blood cell count]4.6%131
11. Convulsion[seizure]4.6%129
12. Thrombocytopenia[low platelet count]4.1%117
13. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]3.9%110
14. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]3.9%109
15. Death by euthanasia[the animal was euthanized]3.5%100
16. No sign[no clinical sign was reported]3.2%89
17. Behavioural disorder NOS[behaviour change, type not specified]2.8%80
18. Trembling2.7%75
19. Leucocytosis NOS[high white blood cell count]2.6%73
20. Vials, Leaking[a product quality report, not a sign in an animal]2.6%73
21. Weakness2.6%73
22. Elevated total bilirubin[bilirubin above the normal range]2.5%70
23. Weight loss2.4%67
24. Keratoconjunctivitis sicca2.3%66
25. Accidental exposure[exposure that was not intended]2.3%64
26. Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]2.2%61
27. Other abnormal test result NOS[abnormal laboratory result, type not specified]2.2%61
28. Bolus, Abnormal2.1%60
29. Aggression2.1%58
30. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]1.9%55

Pooled across every ingredient set and every report that names the ingredient. One report can list several terms and several drugs; a term here may relate to any of them or to none.

Monthly reports by species, five years

By month of receipt; each panel has its own scale. The newest months are incomplete because FDA posts reports with a delay of three to six months.

Outcomes, report types and ages

Coloured bar: reports naming sulfadimethoxine. Grey bar: all 1,357,245 reports. Outcomes are as stated by the reporter; FDA has not necessarily determined whether any product played a part.

In context

Shares of reports, not of animals treated: how many animals receive the ingredient is not public. Ingredients used in anaesthesia, cancer care or in old animals carry more serious outcomes in their reports for that reason alone.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Ingredient names follow the Green Book; salts and forms are kept as FDA lists them. Drug entries are matched by the active ingredients their unmasked ingredient field discloses. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.