Penicillin G Procaine: adverse event reports in all combinations
Active ingredient, alone and in combinations
Brand names with this ingredient: Quartermaster, Albacillin, Special Formula 17900-Forte, Dry-Mast, Albadry Plus, Norocillin, and 16 more.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
Read this first. FDA says this about the data:
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .
This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.
Contacting a veterinarianHow to report to FDAFDA reports received through . Counts include this ingredient alone and in combinations. Why brand names have no separate count.
From January 1987 to October 2025, FDA received 1,119 adverse event reports that name a drug with penicillin g procaine, alone or in a combination. 3 sets of active ingredients with penicillin g procaine have a drug page.
Of the 1,119 reports, 286 (25.6%) are about cattle. 182 reports are about dogs (16.3%). In January to March 2026, FDA received no reports that name penicillin g procaine, alone or in a combination. The signs that appear in the largest number of the 1,119 reports are "Death", "Suspension, Abnormal" and "Anaphylaxis". A report is not proof that a drug caused a sign.
Fewer than 20 reports named this ingredient in the 12 months before June 2026, so this page gives no change. Reports about dogs are 16.3% of the reports that name this ingredient, and 72.6% of all reports.
Search engines list an ingredient page with 500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.
Reports in the latest closed quarter
| Species | Jan to Mar 2026 | Oct to Dec 2025 | Jan to Mar 2025 |
|---|---|---|---|
| All species | 0 | 2 | 6 |
| Dog | 0 | 0 | 0 |
| Cat | 0 | 0 | 0 |
| Horse | 0 | 0 | 0 |
| Other or not given | 0 | 2 | 6 |
January to March 2026 is the latest closed quarter in the data.
Drug pages with penicillin g procaine
A report names a drug by its set of active ingredients. Each set with penicillin g procaine that has a drug page is in the table, in order of name. The table has 3 sets.
| Active ingredients | Reports, all years | Reports, latest 12 months |
|---|---|---|
| Novobiocin + Penicillin G Procaine | 54 | 0 |
| Penicillin G Benzathine + Penicillin G Procaine | 310 | 0 |
| Penicillin G Procaine | 729 | 1 |
A report can name more than one set, so the counts of the sets can add to more than the count of the page.
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
Signs that the reports list
A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 1,119 reports that list the sign. One report can list more than one sign and more than one drug.
The sign that is in the largest number of the reports comes first.
- Death24.6%275 reports
- Suspension, Abnormal[a product quality report, not a sign in an animal]14.9%167 reports
- Anaphylaxis[sudden severe allergic-type reaction]13%146 reports
- Residues in milk6.9%77 reports
- Injection site swelling[swelling where the injection was given]5.8%65 reports
- Collapse5.6%63 reports
- Injection site abscess[abscess where the injection was given]4.3%48 reports
- Vomiting4.3%48 reports
- Dyspnoea[difficulty breathing]3.3%37 reports
- Ataxia[unsteady, uncoordinated movement]3.1%35 reports
- Convulsion[seizure]2.9%33 reports
- Injection site pain[pain where the injection was given]2.6%29 reports
- Hyperactivity2.2%25 reports
- Respiratory distress2.2%25 reports
Show the next 16 signs
- Shaking2.1%24 reports
- Anorexia[not eating]1.9%21 reports
- Depression[dull, quiet or withdrawn]1.7%19 reports
- Diarrhoea[diarrhea]1.7%19 reports
- Fever1.7%19 reports
- No sign[no clinical sign was reported]1.7%19 reports
- Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]1.6%18 reports
- Recumbency[lying down and unable or unwilling to rise]1.6%18 reports
- Product Defect, General[a product quality report, not a sign in an animal]1.5%17 reports
- Mammary gland oedema1.4%16 reports
- Urticaria[hives]1.4%16 reports
- Accidental exposure[exposure that was not intended]1.3%15 reports
- Hypersalivation[drooling]1.3%15 reports
- Restlessness1.3%15 reports
- Trembling1.3%15 reports
- Vials, Damaged[a product quality report, not a sign in an animal]1.3%15 reports
Reports by species
Reports for each month, Jul 2021 to Jun 2026
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
No chart: no month has 5 or more reports.
The month is the month in which FDA received the report. Each chart has its own scale. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Reports by year
- Dog
- Cat
- Horse
- Other or not given
| Year | Dog | Cat | Horse | Other or not given | All species |
|---|---|---|---|---|---|
| 2025 | 0 | 0 | 0 | 9 | 9 |
| 2024 | 1 | 0 | 0 | 12 | 13 |
| 2023 | 0 | 0 | 0 | 12 | 12 |
| 2022 | 3 | 0 | 0 | 9 | 12 |
| 2021 | 0 | 0 | 0 | 10 | 10 |
| 2020 | 1 | 0 | 0 | 5 | 6 |
| 2019 | 2 | 1 | 0 | 15 | 18 |
| 2018 | 3 | 1 | 0 | 16 | 20 |
| 2017 | 4 | 1 | 0 | 15 | 20 |
| 2016 | 7 | 0 | 1 | 18 | 26 |
| 2015 | 3 | 1 | 0 | 7 | 11 |
| 2014 | 6 | 2 | 2 | 10 | 20 |
| 2013 | 1 | 3 | 2 | 20 | 26 |
| 2012 | 6 | 1 | 2 | 11 | 20 |
| 2011 | 3 | 1 | 4 | 27 | 35 |
| 2010 | 4 | 1 | 1 | 36 | 42 |
| 2009 | 4 | 2 | 1 | 52 | 59 |
| 2008 | 2 | 1 | 7 | 31 | 41 |
| 2007 | 14 | 1 | 2 | 18 | 35 |
| 2006 | 7 | 0 | 6 | 47 | 60 |
| 2005 | 10 | 0 | 3 | 20 | 33 |
| 2004 | 5 | 0 | 13 | 21 | 39 |
| 2003 | 9 | 0 | 10 | 10 | 29 |
| 2002 | 3 | 1 | 1 | 6 | 11 |
| 2001 | 3 | 1 | 12 | 22 | 38 |
| 2000 | 7 | 6 | 13 | 22 | 48 |
| 1999 | 7 | 3 | 8 | 25 | 43 |
| 1998 | 11 | 0 | 17 | 60 | 88 |
| 1997 | 11 | 1 | 14 | 50 | 76 |
| 1996 | 8 | 3 | 5 | 14 | 30 |
| 1995 | 10 | 2 | 11 | 18 | 41 |
| 1994 | 4 | 1 | 6 | 10 | 21 |
| 1993 | 4 | 1 | 4 | 6 | 15 |
| 1992 | 3 | 0 | 5 | 8 | 16 |
| 1991 | 1 | 1 | 3 | 12 | 17 |
| 1990 | 5 | 0 | 2 | 14 | 21 |
| 1989 | 6 | 1 | 0 | 6 | 13 |
| 1988 | 1 | 0 | 5 | 8 | 14 |
| 1987 | 3 | 1 | 9 | 18 | 31 |
2025 has the reports that FDA received through Oct 2025. Download the years (CSV)
What the reports record
Outcome at the time of the report
- Recovered/Normal4.1%46
- Recovered with Sequela[recovered, with a lasting effect]0.3%3
- Ongoing0.8%9
- Died26.3%294
- Euthanized0.3%3
- Outcome Unknown2%22
An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 1,119 reports that name penicillin g procaine.
Kind of report
- Safety issue69.8%781
- Lack of expected effectiveness0.4%4
- Both safety and lack of expected effectiveness0.2%2
- Manufacturing or product defect29.4%329
- Other0.3%3
Age of the animal
- Under 1 year12.4%139
- 1 to 3 years10.3%115
- 4 to 7 years8.8%98
- 8 to 11 years5.2%58
- 12 years and over3.8%43
- Age not given59.5%666
Each share of kind and age is of the 1,119 reports that name penicillin g procaine.
Approved animal drugs with this active ingredient (FDA Green Book)
This section is reference data. It has no report count.
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.
Brand names
- Quartermaster
- Albacillin
- Special Formula 17900-Forte
- Dry-Mast
- Albadry Plus
- Norocillin
- Go-dry
- MASTI-CLEAR
- Longicil Fortified
- Pen-G Max
- Dura-Biotic
- Flo-cillin
The Green Book has 10 more brand names with this active ingredient. Brand names A to Z
What the Green Book records give
- Applications with an approval in force
- 16
- Approved species
- Cattle, Dogs, Cats, Equids, Sheep, Swine, Horses
- Dose forms
- Liquid (Suspension), Suspension, Injectable Suspension, Liquid, Ointment
- Routes
- Intramammary, Intramuscular, Subcutaneous, Topical
- Sale
- RX (prescription)
- Earliest approval date in the records
The species, dose forms and routes are the words of the Green Book records for all the applications together. One product can have fewer. The label of a product gives its approved use.
| Brand name | Active ingredients | Sponsor | Approved species | Application |
|---|---|---|---|---|
| Quartermaster Suspension | Dihydrostreptomycin Sulfate, Penicillin G Procaine | HQ Specialty Pharma Corp. | Cattle | NADA 055-028 |
| Albacillin Suspension; Special Formula 17900-Forte Suspension | Novobiocin Sodium, Penicillin G Procaine | Zoetis Inc. | Cattle | NADA 055-072 |
| Dry-Mast | Dihydrostreptomycin Sulfate, Penicillin G Procaine | HQ Specialty Pharma Corp. | Cattle | NADA 055-097 |
| Albadry Plus Suspension | Novobiocin Sodium, Penicillin G Procaine | Zoetis Inc. | Cattle | NADA 055-098 |
| Norocillin | Penicillin G Procaine | Norbrook Laboratories, Ltd. | Horses, Cattle, Swine, Sheep | NADA 065-010 |
| Go-dry; MASTI-CLEAR | Penicillin G Procaine | HQ Specialty Pharma Corp. | Cattle | NADA 065-081 |
| Longicil Fortified | Penicillin G Benzathine, Penicillin G Procaine | Zoetis Inc. | Cattle | NADA 065-087 |
| Pen-G Max | Penicillin G Procaine | Huvepharma EOOD | Dogs, Cats, Horses, Cattle, Swine, Sheep | NADA 065-110 |
| Forte Topical Ointment | Hydrocortisone Acetate, Neomycin Sulfate, Penicillin G Procaine, Polymyxin B Sulfate | Zoetis Inc. | Dogs, Cats | NADA 065-119 |
| Crystalline Pro Penicillin G | Penicillin G Procaine | Zoetis Inc. | Dogs, Cats, Horses | NADA 065-130 |
| Dura-Biotic; Flo-cillin | Penicillin G Benzathine, Penicillin G Procaine | Zoetis Inc. | Dogs, Horses, Cattle | NADA 065-169 |
| Crysticillin 300 A.S. | Penicillin G Procaine | Zoetis Inc. | Dogs, Cats, Horses, Cattle, Swine, Sheep | NADA 065-174 |
| Formula A-34; Uni-Biotic 4 Dose; Herdsman’s Choice; Dry-A-Cillin | Penicillin G Procaine | Bimeda Animal Health Ltd. | Cattle | NADA 065-383 |
| Dual-Cillin; Pen BP-48 | Penicillin G Benzathine, Penicillin G Procaine | Huvepharma EOOD | Cattle | NADA 065-498 |
| Pro-Pen-G | Penicillin G Procaine | Bimeda Animal Health Ltd. | Horses, Cattle, Swine, Sheep | NADA 065-505 |
| Combi-Pen-48 | Penicillin G Benzathine, Penicillin G Procaine | Bimeda Animal Health Ltd. | Cattle | NADA 065-506 |
| Bonaid & Zinc Bacitracin & Penicillinapproval withdrawn | Bacitracin Zinc, Buquinolate, Penicillin G Procaine | Proctor & Gamble Pharmaceuticals, Inc. | Not in the list of major species | NADA 035-315 |
| Bonaid & Penicillinapproval withdrawn | Buquinolate, Penicillin G Procaine | Proctor & Gamble Pharmaceuticals, Inc. | Not in the list of major species | NADA 035-317 |
| Bonaid & Bacitracin MD & Penapproval withdrawn | Bacitracin methylenedisalicylate, Buquinolate, Penicillin G Procaine | Proctor & Gamble Pharmaceuticals, Inc. | Not in the list of major species | NADA 035-327 |
| CSP 250; CSP 500approval withdrawn | Chlortetracycline Hydrochloride, Penicillin G Procaine, Sulfathiazole | Zoetis Inc. | Swine | NADA 039-077 |
| Penicillin 100 Type A Medicated Article; Penicillin G Procaine 50 Type A Medicated Articleapproval withdrawn | Penicillin G Procaine | Zoetis Inc. | Swine, Chickens, Turkeys | NADA 046-666 |
| Penicillin G Procaine 50% Type A Medicated Articleapproval withdrawn | Penicillin G Procaine | Phibro Animal Health Corp. | Swine, Chickens, Turkeys | NADA 046-668 |
| Rainbrook Broiler Premix No.1approval withdrawn | Amprolium, Arsanilic Acid, Ethopabate, Penicillin G Procaine, Streptomycin | Stockton Hay & Grain Co. | Chickens | NADA 049-462 |
| Bicillin Fortifiedapproval withdrawn | Penicillin G Benzathine, Penicillin G Procaine | Wyeth Laboratories | Dogs, Horses, Cattle | NADA 055-008 |
| Aqua-Mast; Hanfords Four-Penapproval withdrawn | Penicillin G Procaine | G.C. Hanford Mfg. Co. | Cattle | NADA 065-465 |
| True Antibiotic Formula #10approval withdrawn | Penicillin G Procaine | Boehringer Ingelheim Animal Health USA Inc. | Not in the list of major species | NADA 065-466 |
| Benza-Penapproval withdrawn | Penicillin G Benzathine, Penicillin G Procaine | Walco International, Inc. | Dogs, Horses, Cattle | NADA 065-488 |
| Jetpen; Penicillin G Procaine Aqueous Suspensionapproval withdrawn | Penicillin G Procaine | Norbrook Laboratories, Ltd. | Horses, Cattle, Swine, Sheep | NADA 065-493 |
| Tandem Penapproval withdrawn | Penicillin G Benzathine, Penicillin G Procaine | Norbrook Laboratories, Ltd. | Dogs, Horses, Cattle | NADA 065-500 |
| Chlorachel 250 Swine; Pficlor 1000; Pficlor 250; Pficlor-SP 250approval withdrawn | Chlortetracycline Calcium Complex, Penicillin G Procaine, Sulfamethazine | Zoetis Inc. | Swine | NADA 091-668 |
| Nicarbazin plus Penicillin G Procaine plus 3-Nitroapproval withdrawn | Nicarbazin, Penicillin G Procaine, Roxarsone | Phibro Animal Health Corp. | Chickens | NADA 098-371 |
| Nicarbazin plus Penicillin G Procaineapproval withdrawn | Nicarbazin, Penicillin G Procaine | Phibro Animal Health Corp. | Chickens | NADA 098-374 |
| Aureozolapproval withdrawn | Chlortetracycline Hydrochloride, Penicillin G Procaine, Sulfathiazole | Zoetis Inc. | Swine | ANADA 200-140 |
| Aureozol 500 Granularapproval withdrawn | Chlortetracycline Calcium Complex, Penicillin G Procaine, Sulfathiazole | Zoetis Inc. | Swine | ANADA 200-167 |
FDA pages for this ingredient
- How to Report Animal Drug and Device Side Effects and Product ProblemsThe FDA page that tells an owner or a veterinarian how to send a report.
- Green Book record of NADA 055-028The FDA record of the application for Quartermaster Suspension.
- Green Book record of NADA 055-072The FDA record of the application for Albacillin Suspension, Special Formula 17900-Forte Suspension.
- Green Book record of NADA 055-097The FDA record of the application for Dry-Mast.
- Green Book record of NADA 055-098The FDA record of the application for Albadry Plus Suspension.
- Green Book record of NADA 065-010The FDA record of the application for Norocillin.
- Green Book record of NADA 065-081The FDA record of the application for Go-dry, MASTI-CLEAR.
- Animal Drugs @ FDAThe search page of the Green Book, the FDA list of approved animal drugs.
The site checked these addresses on . The links open in a new tab.
Cite this page
Pet Drug Reports. Penicillin G Procaine, all combinations: adverse event reports that FDA received. https://petdrugreports.com/ingredient/penicillin-g-procaine/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .
Where the data come from
The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. Ingredient names follow the Green Book, with salts and forms as FDA lists them.
The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.
Questions about these reports
- Which brand are these reports about?
The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. The Green Book section of this page lists brand names with this active ingredient.
- Do the reports show that the ingredient caused the signs?
No. A report can name more than one drug, and a drug can have more than one active ingredient. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices
- How many reports did FDA receive in the latest 12 months?
FDA received 2 reports in the 12 months to June 2026. It received 13 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
- What kinds of report are in the count?
Of the 1,119 reports received from January 1987 to October 2025, 69.8% are about a safety issue only. 0.5% are about a lack of expected effectiveness, alone or with a safety issue. 29.4% are about a defect of the product or its package.