October 2024: adverse event reports received

7,101 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

7,101reports received

6,154same month a year earlier+15%

6,615monthly average, preceding 12 months

68.4%concern dogscats 17.7%

FDA's database holds 7,101 adverse event reports received in October 2024, against 6,154 in the same month a year earlier and a monthly average of 6,615 over the preceding 12 months.

68.4% of the month's reports concern dogs, 17.7% cats and 1.2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were pyrantel pamoate + sarolaner (986), bedinvetmab (768) and fluralaner (603), and the terms listed most often were vomiting (719), lack of efficacy (ectoparasite) - flea (595) and lethargy (547). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Pyrantel Pamoate + Sarolaner	986	13.9%
Bedinvetmab	768	10.8%
Fluralaner	603	8.5%
Ivermectin + Pyrantel Pamoate	484	6.8%
Afoxolaner + Moxidectin + Pyrantel Pamoate	366	5.2%
Afoxolaner	325	4.6%
Moxidectin	313	4.4%
Oclacitinib	295	4.2%
Gabapentin	262	3.7%
Milbemycin Oxime + Praziquantel	238	3.4%
Frunevetmab	218	3.1%
Nitenpyram	177	2.5%
Carprofen	174	2.5%
Velagliflozin	154	2.2%
Sarolaner + Selamectin	149	2.1%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting10.1%719
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]8.4%595
Lethargy[unusually tired or inactive]7.7%547
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]7.6%540
Diarrhoea[diarrhea]5.8%409
Lack of efficacy - NOS[the product did not have the expected effect]5.7%405
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4%284
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]4%281
Seizure NOS[seizure, type not specified]3.5%250
Death3.4%238
Not eating3%216
Intentional misuse[use that was knowingly different from the label]2.9%206
Death by euthanasia[the animal was euthanized]2.8%202
Weight loss2.7%194
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.5%175

Single ingredients, pooled

Pyrantel Pamoate26.9%1,908

Sarolaner17.4%1,234

Moxidectin11.5%818

Bedinvetmab10.8%768

Afoxolaner9.5%676

Fluralaner9.4%665

Praziquantel8.1%577

Ivermectin7.5%535

Milbemycin Oxime6.6%471

Oclacitinib4.2%295

Gabapentin3.7%262

Selamectin3.1%222

Species

Dog68.4%4,858

Cat17.7%1,254

Horse1.2%82

Other or not given12.8%907

Questions about October 2024

How many animal drug adverse event reports did FDA receive in October 2024?

7,101 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 6,154.

Which drugs were named most often?

By active ingredient: pyrantel pamoate + sarolaner (986), bedinvetmab (768), fluralaner (603), ivermectin + pyrantel pamoate (484) and afoxolaner + moxidectin + pyrantel pamoate (366). Brands are masked in the public data.

Which signs were listed most often?

vomiting (719), lack of efficacy (ectoparasite) - flea (595), lethargy (547), lack of efficacy (endoparasite) - heartworm (540) and diarrhoea (409).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.