October 1998: adverse event reports received

433 reports in the openFDA release of 28 Sep 2026

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An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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433reports received

577same month a year earlier-25%

607monthly average, preceding 12 months

33.7%concern dogscats 8.5%

FDA's database holds 433 adverse event reports received in October 1998, against 577 in the same month a year earlier and a monthly average of 607 over the preceding 12 months.

33.7% of the month's reports concern dogs, 8.5% cats and 9.9% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were doramectin (109), carprofen (49) and flunixin meglumine (31), and the terms listed most often were lack of efficacy (ectoparasite) - lice (81), death (61) and pruritus (60). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Doramectin	109	25.2%
Carprofen	49	11.3%
Flunixin Meglumine	31	7.2%
Moxidectin	23	5.3%
Pyrantel Pamoate	21	4.8%
Etodolac	18	4.2%
Tilmicosin Phosphate	18	4.2%
Melarsomine Dihydrochloride	13	3%
Lufenuron	9	2.1%
Oxytetracycline Hydrochloride	8	1.8%
Selegiline Hydrochloride	8	1.8%
Tiletamine Hydrochloride + Zolazepam Hydrochloride	8	1.8%
Cephapirin Benzathine	6	1.4%
Isoflurane	6	1.4%
Ivermectin + Pyrantel Pamoate	6	1.4%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Lack of efficacy (ectoparasite) - lice[the product did not have the expected effect: lice]18.7%81
Death14.1%61
Pruritus[itching]13.9%60
Alopecia NOS[hair loss, type not specified]11.1%48
Accidental exposure[exposure that was not intended]9.7%42
Vomiting7.9%34
Anorexia[not eating]6.9%30
Unclassifiable adverse event[event that fits no dictionary term]6.5%28
Depression[dull, quiet or withdrawn]6.2%27
Diarrhoea[diarrhea]6%26
Ineffective, parasite(s) NOS[legacy FDA term: the product did not have the expected effect (parasite(s) nos)]4.8%21
No sign[no clinical sign was reported]4.4%19
Ataxia[unsteady, uncoordinated movement]4.2%18
Death by euthanasia[the animal was euthanized]3.9%17
Fever3.7%16

Single ingredients, pooled

Doramectin25.2%109

Carprofen11.3%49

Flunixin Meglumine7.2%31

Pyrantel Pamoate6.5%28

Moxidectin5.3%23

Etodolac4.2%18

Tilmicosin Phosphate4.2%18

Lufenuron3.5%15

Melarsomine Dihydrochloride3%13

Milbemycin Oxime2.5%11

Ivermectin2.3%10

Oxytetracycline Hydrochloride1.8%8

Species

Dog33.7%146

Cat8.5%37

Horse9.9%43

Other or not given47.8%207

Questions about October 1998

How many animal drug adverse event reports did FDA receive in October 1998?

433 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 577.

Which drugs were named most often?

By active ingredient: doramectin (109), carprofen (49), flunixin meglumine (31), moxidectin (23) and pyrantel pamoate (21). Brands are masked in the public data.

Which signs were listed most often?

lack of efficacy (ectoparasite) - lice (81), death (61), pruritus (60), alopecia NOS (48) and accidental exposure (42).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.