October 2001: adverse event reports received

1,226 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,226reports received

1,495same month a year earlier-18%

1,306monthly average, preceding 12 months

58.9%concern dogscats 17.3%

FDA's database holds 1,226 adverse event reports received in October 2001, against 1,495 in the same month a year earlier and a monthly average of 1,306 over the preceding 12 months.

58.9% of the month's reports concern dogs, 17.3% cats and 2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (421), carprofen (177) and moxidectin (100), and the terms listed most often were vomiting (167), accidental exposure (161) and depression (147). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	421	34.3%
Carprofen	177	14.4%
Moxidectin	100	8.2%
(S) - methoprene	63	5.1%
Amoxicillin	39	3.2%
Melarsomine Dihydrochloride	38	3.1%
Milbemycin Oxime	29	2.4%
Enrofloxacin	18	1.5%
Tilmicosin Phosphate	18	1.5%
Selegiline Hydrochloride	17	1.4%
Medetomidine	16	1.3%
Sulfadimethoxine	15	1.2%
Etodolac	12	1%
Ivermectin + Pyrantel Pamoate	11	0.9%
Lufenuron + Milbemycin Oxime	11	0.9%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting13.6%167
Accidental exposure[exposure that was not intended]13.1%161
Depression[dull, quiet or withdrawn]12%147
Death9.1%112
No sign[no clinical sign was reported]8.1%99
Anorexia[not eating]7.3%89
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]6.5%80
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.2%76
Unclassifiable adverse event[event that fits no dictionary term]5.3%65
Diarrhoea[diarrhea]5.1%62
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.3%53
Ataxia[unsteady, uncoordinated movement]4.2%51
Fever3.8%47
Pruritus[itching]3.5%43
Underfilling, Tubes[a product quality report, not a sign in an animal]3.4%42

Single ingredients, pooled

Selamectin34.3%421

Carprofen14.4%177

Moxidectin8.2%100

(S) - methoprene5.1%63

Milbemycin Oxime3.3%40

Amoxicillin3.2%39

Melarsomine Dihydrochloride3.1%38

Enrofloxacin2%24

Ivermectin1.9%23

Pyrantel Pamoate1.6%20

Tilmicosin Phosphate1.5%18

Selegiline Hydrochloride1.4%17

Species

Dog58.9%722

Cat17.3%212

Horse2%24

Other or not given21.9%268

Questions about October 2001

How many animal drug adverse event reports did FDA receive in October 2001?

1,226 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,495.

Which drugs were named most often?

By active ingredient: selamectin (421), carprofen (177), moxidectin (100), (s) - methoprene (63) and amoxicillin (39). Brands are masked in the public data.

Which signs were listed most often?

vomiting (167), accidental exposure (161), depression (147), death (112) and no sign (99).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.