November 2024: adverse event reports received

5,748 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

5,748reports received

5,744same month a year earlier+0%

6,694monthly average, preceding 12 months

65.8%concern dogscats 19.6%

FDA's database holds 5,748 adverse event reports received in November 2024, against 5,744 in the same month a year earlier and a monthly average of 6,694 over the preceding 12 months.

65.8% of the month's reports concern dogs, 19.6% cats and 1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were pyrantel pamoate + sarolaner (810), bedinvetmab (577) and fluralaner (426), and the terms listed most often were vomiting (593), lack of efficacy (endoparasite) - heartworm (448) and lethargy (424). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Pyrantel Pamoate + Sarolaner	810	14.1%
Bedinvetmab	577	10%
Fluralaner	426	7.4%
Ivermectin + Pyrantel Pamoate	382	6.6%
Afoxolaner	271	4.7%
Moxidectin	268	4.7%
Afoxolaner + Moxidectin + Pyrantel Pamoate	241	4.2%
Oclacitinib	241	4.2%
Milbemycin Oxime + Praziquantel	225	3.9%
Gabapentin	203	3.5%
Velagliflozin	178	3.1%
Frunevetmab	163	2.8%
Carprofen	155	2.7%
Mirtazapine	142	2.5%
Maropitant	131	2.3%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting10.3%593
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]7.8%448
Lethargy[unusually tired or inactive]7.4%424
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.7%386
Diarrhoea[diarrhea]6%346
Lack of efficacy - NOS[the product did not have the expected effect]5.5%315
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]4.3%248
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4%232
Seizure NOS[seizure, type not specified]4%230
Not eating3.2%184
Intentional misuse[use that was knowingly different from the label]3%175
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.9%169
Weight loss2.9%166
Death2.8%162
Death by euthanasia[the animal was euthanized]2.8%161

Single ingredients, pooled

Pyrantel Pamoate25.9%1,488

Sarolaner17.6%1,013

Moxidectin10.7%613

Bedinvetmab10%577

Afoxolaner8.7%502

Fluralaner8.3%479

Praziquantel8.2%471

Ivermectin7.3%417

Milbemycin Oxime6.5%371

Oclacitinib4.2%241

Selamectin3.6%206

Gabapentin3.5%203

Species

Dog65.8%3,784

Cat19.6%1,124

Horse1%56

Other or not given13.6%784

Questions about November 2024

How many animal drug adverse event reports did FDA receive in November 2024?

5,748 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 5,744.

Which drugs were named most often?

By active ingredient: pyrantel pamoate + sarolaner (810), bedinvetmab (577), fluralaner (426), ivermectin + pyrantel pamoate (382) and afoxolaner (271). Brands are masked in the public data.

Which signs were listed most often?

vomiting (593), lack of efficacy (endoparasite) - heartworm (448), lethargy (424), lack of efficacy (ectoparasite) - flea (386) and diarrhoea (346).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.