October 2018: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,548 adverse event reports for animal drugs in October 2018. It received 6,462 reports in October 2017. The average of the 12 months before October 2018 is 5,941 reports for each month.

Of the 6,548 reports, 74.8% are about dogs, 10.6% are about cats and 0.8% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Apr 2017 to Apr 2019. The column with the outline is October 2018.

Reports by species

Dog74.8%4,897
Cat10.6%697
Horse0.8%52
Other species, or species not given13.8%902

Drug pages with reports received in October 2018

The table has every drug page with 10 or more reports that FDA received in October 2018, in order of name. No count decides which drug is in the table. The table has 77 drug pages.

Show the 77 drug pages

Drug pages with 10 or more reports received in October 2018, in order of name
Active ingredients	Reports received in October 2018
(S) - methoprene	26
Afoxolaner	627
Amoxicillin Trihydrate + Clavulanate Potassium	43
Buprenorphine	16
Butorphanol Tartrate	19
Capromorelin	23
Carprofen	99
Cefovecin sodium	55
Cefpodoxime proxetil	21
Ceftiofur Crystalline Free Acid	11
Cephalexin	18
Cyclosporine	65
Deracoxib	29
Desoxycorticosterone Pivalate	45
Dexamethasone	21
Dexamethasone + Neomycin Sulfate + Thiabendazole	12
Dexmedetomidine hydrochloride	18
Diphenhydramine	28
Doxycycline	35
Emodepside + Praziquantel	35
Enrofloxacin	24
Eprinomectin + Praziquantel	11
Estriol	15
Famotidine	12
Febantel + Praziquantel + Pyrantel Pamoate	45
Fenbendazole	11
Firocoxib	20
Florfenicol + Mometasone furoate + Terbinafine	46
Florfenicol + Terbinafine	31
Fluralaner	907
Gabapentin	41
Grapiprant	107
Imidacloprid	66
Imidacloprid + Moxidectin	149
Insulin	47
Isoflurane	10
Ivermectin	54
Ivermectin + Praziquantel + Pyrantel Pamoate	22
Ivermectin + Pyrantel Pamoate	986
Ketamine Hydrochloride	10
Ketoconazole	12
Levothyroxine sodium	14
Lotilaner	81
Lufenuron + Milbemycin Oxime	163
Lufenuron + Milbemycin Oxime + Praziquantel	85
Maropitant	76
Melarsomine Dihydrochloride	100
Meloxicam	42
Metronidazole	22
Milbemycin Oxime	75
Milbemycin Oxime + Praziquantel	354
Milbemycin Oxime + Spinosad	589
Mirtazapine	17
Monensin	22
Moxidectin	228
Nitenpyram	213
Oclacitinib	218
Omeprazole	11
Pergolide mesylate	14
Phenobarbital	13
Pimobendan	28
Polysulfated Glycosaminoglycan	24
Praziquantel	29
Praziquantel + Pyrantel Pamoate	24
Prednisolone	25
Prednisone	67
Pyrantel Pamoate	16
Robenacoxib	17
Sarolaner	375
Selamectin	232
Sodium Chloride	32
Spinosad	153
Sucralfate	11
Telmisartan	16
Tramadol	29
Trazodone	13
Trilostane	87

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,548 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting17.7%1,157 reports
Lethargy[unusually tired or inactive]7.9%518 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]6.5%427 reports
Ineffective, hooks[legacy FDA term: the product did not have the expected effect (hooks)]6%395 reports
Seizure NOS[seizure, type not specified]5.5%363 reports
Diarrhoea[diarrhea]5.2%339 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]5%327 reports
Lack of efficacy (flea)[the product did not have the expected effect: fleas]3%198 reports
Unpalatable[legacy FDA term: the animal would not take it]2.9%188 reports
Ataxia[unsteady, uncoordinated movement]2.8%182 reports
Anorexia[not eating]2.4%160 reports
Death2.4%156 reports
Product problem[a product quality report, not a sign in an animal]2.3%152 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.3%150 reports

Show the next 1 signs

Behavioural disorder NOS[behaviour change, type not specified]2.2%147 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in October 2018, in order of name. It has 77 ingredients.

Show the 77 ingredients

The same month in other years

Cite this page

Pet Drug Reports. October 2018: adverse event reports for animal drugs. https://petdrugreports.com/month/2018-10/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for October 2018 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 1,157 reports of the 6,548 reports of October 2018 (17.7%).