October 2022: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 5,014 adverse event reports for animal drugs in October 2022. It received 4,963 reports in October 2021. The average of the 12 months before October 2022 is 4,848 reports for each month.

Of the 5,014 reports, 73% are about dogs, 13% are about cats and 1.2% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Apr 2021 to Apr 2023. The column with the outline is October 2022.

Reports by species

Dog73%3,662
Cat13%651
Horse1.2%62
Other species, or species not given12.7%639

Drug pages with reports received in October 2022

The table has every drug page with 10 or more reports that FDA received in October 2022, in order of name. No count decides which drug is in the table. The table has 80 drug pages.

Show the 80 drug pages

Drug pages with 10 or more reports received in October 2022, in order of name
Active ingredients	Reports received in October 2022
(S) - methoprene	15
Afoxolaner	294
Alfaxalone	17
Amoxicillin Trihydrate + Clavulanate Potassium	14
Atipamezole Hydrochloride	17
Bupivacaine	11
Buprenorphine	160
Butorphanol Tartrate	49
Capromorelin	23
Carprofen	84
Cefovecin sodium	50
Cefpodoxime proxetil	13
Ceftiofur Crystalline Free Acid	13
Cephalexin	12
Cyclosporine	43
Dexamethasone	17
Dexmedetomidine	41
Dexmedetomidine hydrochloride	27
Diphenhydramine	18
Doxycycline	37
Emodepside + Praziquantel	13
Enrofloxacin	12
Febantel + Praziquantel + Pyrantel Pamoate	23
Firocoxib	12
Florfenicol + Mometasone furoate + Terbinafine	58
Fluoxetine hydrochloride	12
Fluralaner	414
Fluralaner + Moxidectin	43
Frunevetmab	64
Gabapentin	46
Grapiprant	54
Hydromorphone	18
Imidacloprid	61
Imidacloprid + Moxidectin	67
Insulin	49
Isoflurane	59
Ivermectin	35
Ivermectin + Praziquantel + Pyrantel Pamoate	13
Ivermectin + Pyrantel Pamoate	638
Ketamine Hydrochloride	47
Lotilaner	122
Lufenuron + Milbemycin Oxime	62
Lufenuron + Milbemycin Oxime + Praziquantel	54
Maropitant	84
Medetomidine hydrochloride + Vatinoxan hydrochloride	23
Melarsomine Dihydrochloride	96
Meloxicam	31
Metronidazole	13
Midazolam	18
Milbemycin Oxime	18
Milbemycin Oxime + Praziquantel	239
Milbemycin Oxime + Spinosad	132
Mirtazapine	17
Monensin	11
Moxidectin	332
Moxidectin + Pyrantel Pamoate + Sarolaner	10
Nitenpyram	149
Oclacitinib	132
Omeprazole	19
Pergolide mesylate	14
Pimobendan	64
Polysulfated Glycosaminoglycan	40
Praziquantel	18
Praziquantel + Pyrantel Pamoate	21
Prednisolone	18
Prednisone	60
Propofol	51
Pyrantel Pamoate	12
Pyrantel Pamoate + Sarolaner	810
Robenacoxib	35
Sarolaner	69
Sarolaner + Selamectin	110
Selamectin	68
Sodium Chloride	84
Spinosad	26
Tigilanol tiglate	26
Tiletamine Hydrochloride + Zolazepam Hydrochloride	13
Trilostane	64
Tulathromycin	20
Verdinexor	13

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 5,014 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting12.7%636 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]12.4%620 reports
Lethargy[unusually tired or inactive]7.1%356 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]7%353 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.5%325 reports
Diarrhoea[diarrhea]5.1%256 reports
Seizure NOS[seizure, type not specified]4%201 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]3.9%197 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.5%174 reports
Death3.2%162 reports
Not eating3%150 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.9%144 reports
Containers, Damaged[a product quality report, not a sign in an animal]2.6%129 reports
Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]2.4%122 reports

Show the next 1 signs

Behavioural disorder NOS[behaviour change, type not specified]2.4%121 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in October 2022, in order of name. It has 80 ingredients.

Show the 80 ingredients

The same month in other years

Cite this page

Pet Drug Reports. October 2022: adverse event reports for animal drugs. https://petdrugreports.com/month/2022-10/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for October 2022 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 636 reports of the 5,014 reports of October 2022 (12.7%).