October 2007: adverse event reports received

2,613 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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2,613reports received

2,092same month a year earlier+25%

2,219monthly average, preceding 12 months

72.8%concern dogscats 10.4%

FDA's database holds 2,613 adverse event reports received in October 2007, against 2,092 in the same month a year earlier and a monthly average of 2,219 over the preceding 12 months.

72.8% of the month's reports concern dogs, 10.4% cats and 1.8% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were ivermectin + pyrantel pamoate (412), selamectin (252) and milbemycin oxime (222), and the terms listed most often were vomiting (406), ineffective, heartworm larvae (350) and depression (292). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Ivermectin + Pyrantel Pamoate	412	15.8%
Selamectin	252	9.6%
Milbemycin Oxime	222	8.5%
Cyclosporine	134	5.1%
Carprofen	130	5%
Firocoxib	90	3.4%
Maropitant	88	3.4%
Melarsomine Dihydrochloride	78	3%
Meloxicam	74	2.8%
Lufenuron + Milbemycin Oxime	70	2.7%
Deracoxib	68	2.6%
Dirlotapide	66	2.5%
Imidacloprid + Moxidectin	59	2.3%
Ivermectin	43	1.6%
Ivermectin + Praziquantel + Pyrantel Pamoate	43	1.6%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting15.5%406
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]13.4%350
Depression[dull, quiet or withdrawn]11.2%292
Anorexia[not eating]10%260
Diarrhoea[diarrhea]8.2%215
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]6.2%162
Death6%156
Accidental exposure[exposure that was not intended]4.4%115
Death by euthanasia[the animal was euthanized]3.4%89
Convulsion[seizure]3.3%86
Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]3.3%85
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]3.1%81
Ataxia[unsteady, uncoordinated movement]3%78
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]2.8%74
Pruritus[itching]2.8%73

Single ingredients, pooled

Ivermectin20.2%528

Pyrantel Pamoate18.7%488

Milbemycin Oxime11.2%292

Selamectin9.6%252

Cyclosporine5.1%134

Carprofen5%130

Praziquantel4.1%107

Firocoxib3.4%90

Maropitant3.4%88

Lufenuron3.1%81

Melarsomine Dihydrochloride3%78

Meloxicam2.8%74

Species

Dog72.8%1,903

Cat10.4%273

Horse1.8%47

Other or not given14.9%390

Questions about October 2007

How many animal drug adverse event reports did FDA receive in October 2007?

2,613 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 2,092.

Which drugs were named most often?

By active ingredient: ivermectin + pyrantel pamoate (412), selamectin (252), milbemycin oxime (222), cyclosporine (134) and carprofen (130). Brands are masked in the public data.

Which signs were listed most often?

vomiting (406), ineffective, heartworm larvae (350), depression (292), anorexia (260) and diarrhoea (215).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.