August 2012: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,486 adverse event reports for animal drugs in August 2012. It received 5,102 reports in August 2011. The average of the 12 months before August 2012 is 5,027 reports for each month.

Of the 6,486 reports, 77.5% are about dogs, 7.7% are about cats and 0.8% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Feb 2011 to Feb 2013. The column with the outline is August 2012.

Reports by species

Dog77.5%5,026
Cat7.7%497
Horse0.8%54
Other species, or species not given14%909

Drug pages with reports received in August 2012

The table has every drug page with 10 or more reports that FDA received in August 2012, in order of name. No count decides which drug is in the table. The table has 79 drug pages.

Show the 79 drug pages

Drug pages with 10 or more reports received in August 2012, in order of name
Active ingredients	Reports received in August 2012
(S) - methoprene	42
Acepromazine Maleate	14
Amitraz	14
Amitraz + (S) - methoprene	34
Amoxicillin	10
Amoxicillin Trihydrate + Clavulanate Potassium	54
Atipamezole Hydrochloride	14
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	19
Buprenorphine	24
Butorphanol Tartrate	25
Carprofen	145
Cefovecin sodium	61
Cefpodoxime proxetil	32
Ceftiofur Crystalline Free Acid	20
Cephalexin	32
Clindamycin	12
Clomipramine Hydrochloride	30
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate	21
Cyclosporine	199
Deracoxib	25
Dexamethasone	20
Dexmedetomidine hydrochloride	30
Diphenhydramine	40
Doramectin	22
Doxycycline	12
Emodepside + Praziquantel	35
Enalapril Maleate	11
Enrofloxacin	36
Famotidine	25
Febantel + Praziquantel + Pyrantel Pamoate	23
Fenbendazole	33
Firocoxib	53
Fluoxetine hydrochloride	15
Furosemide	11
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	15
Hyaluronate Sodium	10
Hydroxyzine	23
Imidacloprid	14
Imidacloprid + Moxidectin	203
Insulin	25
Isoflurane	21
Ivermectin	183
Ivermectin + Praziquantel + Pyrantel Pamoate	81
Ivermectin + Pyrantel Pamoate	721
Ketamine Hydrochloride	24
Ketoconazole	23
Levothyroxine sodium	34
Lufenuron	22
Lufenuron + Milbemycin Oxime	70
Maropitant	56
Melarsomine Dihydrochloride	100
Meloxicam	169
Methylprednisolone Acetate	15
Metoclopramide	10
Metronidazole	20
Milbemycin Oxime	151
Milbemycin Oxime + Spinosad	2,526
Monensin	13
Moxidectin	96
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide	13
Nitenpyram	76
Omeprazole	13
Orbifloxacin	11
Phenobarbital	16
Pimobendan	23
Polysulfated Glycosaminoglycan	15
Praziquantel + Pyrantel Pamoate	31
Prednisolone + Trimeprazine Tartrate	17
Prednisone	77
Propofol	13
Pyrantel Pamoate	35
Robenacoxib	21
Selamectin	265
Spinosad	896
Sucralfate	12
Toceranib Phosphate	12
Tramadol	40
Triamcinolone Acetonide	23
Trilostane	44

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,486 reports of the month.

The sign that is in the largest number of the reports comes first.

Emesis[vomiting]23.5%1,523 reports
Vomiting14.2%924 reports
Lethargy[unusually tired or inactive]12.7%822 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.2%405 reports
Diarrhoea[diarrhea]6.1%395 reports
Lack of efficacy - NOS[the product did not have the expected effect]5.4%353 reports
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]4.5%295 reports
Anorexia[not eating]3.7%243 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]3.4%218 reports
Behavioural disorder NOS[behaviour change, type not specified]3.2%210 reports
Digestive tract disorder NOS[digestive problem, type not specified]3.2%209 reports
Unpalatable[legacy FDA term: the animal would not take it]3.1%200 reports
Other abnormal test result NOS[abnormal laboratory result, type not specified]3%195 reports
Seizure NOS[seizure, type not specified]2.6%166 reports

Show the next 1 signs

Pruritus[itching]2.4%157 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in August 2012, in order of name. It has 81 ingredients.

Show the 81 ingredients

The same month in other years

Cite this page

Pet Drug Reports. August 2012: adverse event reports for animal drugs. https://petdrugreports.com/month/2012-08/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for August 2012 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Emesis" is in 1,523 reports of the 6,486 reports of August 2012 (23.5%).