August 2023: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,367 adverse event reports for animal drugs in August 2023. It received 6,303 reports in August 2022. The average of the 12 months before August 2023 is 5,212 reports for each month.

Of the 6,367 reports, 68.8% are about dogs, 18.6% are about cats and 0.8% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Feb 2022 to Feb 2024. The column with the outline is August 2023.

Reports by species

Dog68.8%4,378
Cat18.6%1,184
Horse0.8%51
Other species, or species not given11.8%754

Drug pages with reports received in August 2023

The table has every drug page with 10 or more reports that FDA received in August 2023, in order of name. No count decides which drug is in the table. The table has 99 drug pages.

Show the 99 drug pages

Drug pages with 10 or more reports received in August 2023, in order of name
Active ingredients	Reports received in August 2023
(S) - methoprene	38
Acepromazine Maleate	14
Afoxolaner	406
Afoxolaner + Moxidectin + Pyrantel Pamoate	12
Alfaxalone	17
Amoxicillin	11
Amoxicillin Trihydrate + Clavulanate Potassium	18
Atipamezole Hydrochloride	25
Betamethasone Acetate + Florfenicol + Terbinafine	13
Bexagliflozin	122
Buprenorphine	99
Butorphanol Tartrate	74
Capromorelin	34
Carprofen	105
Cefovecin sodium	64
Cefpodoxime proxetil	16
Ceftiofur Crystalline Free Acid	16
Clotrimazole + Gentamicin	10
Cyclosporine	44
Dexamethasone	22
Dexamethasone Sodium Phosphate	11
Dexmedetomidine	35
Dexmedetomidine hydrochloride	25
Diphenhydramine	33
Doxycycline	34
Emodepside + Praziquantel	18
Enrofloxacin	19
Eprinomectin + Esafoxolaner + Praziquantel	114
Estriol	12
Famotidine	32
Febantel + Praziquantel + Pyrantel Pamoate	30
Fenbendazole	12
Firocoxib	10
Florfenicol + Mometasone furoate + Terbinafine	43
Fluoxetine hydrochloride	10
Fluralaner	690
Fluralaner + Moxidectin	61
Frunevetmab	282
Furosemide	10
Gabapentin	102
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	17
Grapiprant	47
Hydromorphone	11
Imepitoin	15
Imidacloprid	116
Imidacloprid + Moxidectin	57
Insulin	79
Isoflurane	37
Ivermectin	29
Ivermectin + Pyrantel Pamoate	671
Ketamine Hydrochloride	29
Ketoconazole	19
Levothyroxine sodium	10
Lotilaner	161
Lufenuron + Milbemycin Oxime	61
Lufenuron + Milbemycin Oxime + Praziquantel	79
Maropitant	118
Medetomidine hydrochloride + Vatinoxan hydrochloride	15
Melarsomine Dihydrochloride	62
Meloxicam	35
Methimazole	18
Methylprednisolone Acetate	12
Metronidazole	31
Midazolam	19
Milbemycin Oxime	33
Milbemycin Oxime + Praziquantel	278
Milbemycin Oxime + Spinosad	109
Mirtazapine	23
Moxidectin	378
Moxidectin + Pyrantel Pamoate + Sarolaner	11
Nitenpyram	222
Oclacitinib	169
Omeprazole	34
Ondansetron	12
Phenobarbital	11
Phenylpropanolamine hydrochloride	10
Pimobendan	78
Polysulfated Glycosaminoglycan	39
Praziquantel	44
Praziquantel + Pyrantel Pamoate	30
Prednisolone	28
Prednisone	65
Propofol	37
Pyrantel Pamoate	26
Pyrantel Pamoate + Sarolaner	952
Robenacoxib	25
Ropinirole	11
Sarolaner	103
Sarolaner + Selamectin	162
Selamectin	82
Sodium Chloride	65
Spinosad	16
Sucralfate	13
Tigilanol tiglate	48
Trazodone	13
Trilostane	83
Tulathromycin	23
Velagliflozin	19
Verdinexor	14

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,367 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting13.9%883 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]9.3%595 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]8.6%548 reports
Lethargy[unusually tired or inactive]7.8%495 reports
Diarrhoea[diarrhea]6.9%438 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.9%375 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]4.8%304 reports
Lack of efficacy - NOS[the product did not have the expected effect]3.6%231 reports
Seizure NOS[seizure, type not specified]3.3%213 reports
Not eating3.3%209 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.1%198 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.6%166 reports
Death2.5%160 reports
Lack of efficacy (endoparasite) - tapeworm[the product did not have the expected effect: tapeworms]2.4%155 reports

Show the next 1 signs

Behavioural disorder NOS[behaviour change, type not specified]2.3%149 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in August 2023, in order of name. It has 100 ingredients.

Show the 100 ingredients

The same month in other years

Cite this page

Pet Drug Reports. August 2023: adverse event reports for animal drugs. https://petdrugreports.com/month/2023-08/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for August 2023 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 883 reports of the 6,367 reports of August 2023 (13.9%).