August 2002: adverse event reports received

1,124 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,124reports received

1,528same month a year earlier-26%

1,177monthly average, preceding 12 months

57.9%concern dogscats 14.9%

FDA's database holds 1,124 adverse event reports received in August 2002, against 1,528 in the same month a year earlier and a monthly average of 1,177 over the preceding 12 months.

57.9% of the month's reports concern dogs, 14.9% cats and 2.2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (351), moxidectin (150) and carprofen (141), and the terms listed most often were vomiting (176), depression (157) and anorexia (122). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	351	31.2%
Moxidectin	150	13.3%
Carprofen	141	12.5%
Enrofloxacin	49	4.4%
Dimethyl Sulfoxide + Fluocinolone Acetonide	41	3.6%
Ivermectin + Pyrantel Pamoate	26	2.3%
(S) - methoprene	25	2.2%
Ivermectin	22	2%
Melarsomine Dihydrochloride	20	1.8%
Tilmicosin Phosphate	20	1.8%
Amoxicillin	19	1.7%
Marbofloxacin	17	1.5%
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	15	1.3%
Lufenuron + Milbemycin Oxime	14	1.2%
Medetomidine	14	1.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting15.7%176
Depression[dull, quiet or withdrawn]14%157
Anorexia[not eating]10.9%122
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]9%101
Death8.5%96
Accidental exposure[exposure that was not intended]7.3%82
Diarrhoea[diarrhea]6.7%75
Ataxia[unsteady, uncoordinated movement]5.3%60
Unclassifiable adverse event[event that fits no dictionary term]4.8%54
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.4%50
Anaphylaxis[sudden severe allergic-type reaction]4.4%49
Pruritus[itching]3.9%44
Death by euthanasia[the animal was euthanized]3.8%43
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]3.8%43
Application site alopecia[hair loss where the product was applied]3.7%42

Single ingredients, pooled

Selamectin31.2%351

Moxidectin13.3%150

Carprofen12.5%141

Ivermectin4.6%52

Enrofloxacin4.4%50

Dimethyl Sulfoxide3.6%41

Fluocinolone Acetonide3.6%41

Pyrantel Pamoate3%34

Milbemycin Oxime2.4%27

(S) - methoprene2.2%25

Melarsomine Dihydrochloride1.8%20

Tilmicosin Phosphate1.8%20

Species

Dog57.9%651

Cat14.9%167

Horse2.2%25

Other or not given25%281

Questions about August 2002

How many animal drug adverse event reports did FDA receive in August 2002?

1,124 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,528.

Which drugs were named most often?

By active ingredient: selamectin (351), moxidectin (150), carprofen (141), enrofloxacin (49) and dimethyl sulfoxide + fluocinolone acetonide (41). Brands are masked in the public data.

Which signs were listed most often?

vomiting (176), depression (157), anorexia (122), ineffective, heartworm larvae (101) and death (96).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.