August 2024: adverse event reports received

7,460 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

7,460reports received

6,367same month a year earlier+17%

6,357monthly average, preceding 12 months

69.5%concern dogscats 18.4%

FDA's database holds 7,460 adverse event reports received in August 2024, against 6,367 in the same month a year earlier and a monthly average of 6,357 over the preceding 12 months.

69.5% of the month's reports concern dogs, 18.4% cats and 1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were pyrantel pamoate + sarolaner (932), bedinvetmab (784) and fluralaner (676), and the terms listed most often were vomiting (897), lack of efficacy (ectoparasite) - flea (660) and lethargy (574). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Pyrantel Pamoate + Sarolaner	932	12.5%
Bedinvetmab	784	10.5%
Fluralaner	676	9.1%
Ivermectin + Pyrantel Pamoate	566	7.6%
Afoxolaner	393	5.3%
Moxidectin	360	4.8%
Milbemycin Oxime + Praziquantel	356	4.8%
Afoxolaner + Moxidectin + Pyrantel Pamoate	327	4.4%
Oclacitinib	288	3.9%
Gabapentin	251	3.4%
Frunevetmab	229	3.1%
Nitenpyram	207	2.8%
Lotilaner	197	2.6%
Velagliflozin	183	2.5%
Carprofen	180	2.4%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting12%897
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]8.8%660
Lethargy[unusually tired or inactive]7.7%574
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]7.3%541
Diarrhoea[diarrhea]6.1%456
Lack of efficacy - NOS[the product did not have the expected effect]5.3%392
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.5%333
Seizure NOS[seizure, type not specified]4.1%303
Death by euthanasia[the animal was euthanized]3.6%270
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.2%237
Death3.1%228
Intentional misuse[use that was knowingly different from the label]3%225
Not eating2.9%215
Weight loss2.7%202
Panting2.4%178

Single ingredients, pooled

Pyrantel Pamoate25.6%1,913

Sarolaner16%1,194

Moxidectin11.7%874

Bedinvetmab10.5%784

Fluralaner10.1%751

Afoxolaner9.5%705

Praziquantel9.3%697

Ivermectin8.1%605

Milbemycin Oxime7.5%563

Oclacitinib3.9%288

Gabapentin3.4%251

Selamectin3.1%230

Species

Dog69.5%5,181

Cat18.4%1,375

Horse1%76

Other or not given11.1%828

Questions about August 2024

How many animal drug adverse event reports did FDA receive in August 2024?

7,460 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 6,367.

Which drugs were named most often?

By active ingredient: pyrantel pamoate + sarolaner (932), bedinvetmab (784), fluralaner (676), ivermectin + pyrantel pamoate (566) and afoxolaner (393). Brands are masked in the public data.

Which signs were listed most often?

vomiting (897), lack of efficacy (ectoparasite) - flea (660), lethargy (574), lack of efficacy (endoparasite) - heartworm (541) and diarrhoea (456).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.