Pet Drug Reports

Cattleadverse event reports for animal drugs

Species

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From January 1987 to June 2026, FDA received 31,355 adverse event reports about cattle for animal drugs. That is 2.3% of the 1,378,761 reports that FDA received from January 1987 to June 2026.

In the 12 months to June 2026, FDA received 621 reports about cattle. The signs that appear in the largest number of the 31,355 reports are "Death" and "Lack of efficacy - NOS". A report is not proof that a drug caused a sign.

Since the last update of the FDA data

The site recorded an update of the FDA data on . 6 drug pages with reports about cattle have a different count. Open the update

All updatesFeed of updates (RSS)

Drug pages with reports about cattle

The table has every drug page with 20 or more reports about cattle, in order of name. No count decides which drug is in the table. The table has 84 drug pages.

Show the 84 drug pages
Drug pages with 20 or more reports about cattle, in order of name
Active ingredientsReports about cattle
Albendazole271
Amoxicillin74
Ampicillin Trihydrate166
Amprolium123
Ceftiofur Crystalline Free Acid978
Ceftiofur Hydrochloride669
Ceftiofur Sodium256
Cephapirin Benzathine288
Cephapirin Sodium722
Chlortetracycline48
Chlortetracycline Calcium Complex55
Cloprostenol Sodium131
Clorsulon + Ivermectin298
Cloxacillin Benzathine166
Danofloxacin135
Decoquinate102
Dexamethasone54
Dinoprost Tromethamine910
Doramectin3,238
Doramectin + Levamisole Hydrochloride80
Enrofloxacin236
Eprinomectin1,507
Estradiol262
Estradiol + Norgestomet44
Estradiol + Testosterone24
Estradiol + Trenbolone Acetate163
Estradiol + Trenbolone Acetate + Tylosin Tartrate29
Estradiol + Tylosin Tartrate66
Estradiol Benzoate + Progesterone175
Estradiol Benzoate + Testosterone Propionate27
Estradiol Benzoate + Trenbolone Acetate234
Famphur122
Fenbendazole204
Fenprostalene56
Fenthion75
Florfenicol490
Florfenicol + Flunixin297
Flunixin100
Flunixin Meglumine272
Follicle Stimulating Hormone47
Gamithromycin343
Gonadorelin59
Gonadorelin Hydrochloride47
Hetacillin Potassium32
Ivermectin2,168
Ketoprofen + Tulathromycin204
Lasalocid71
Lasalocid sodium173
Levamisole130
Levamisole Hydrochloride20
Levamisole Phosphate53
Lidocaine22
Lincomycin Hydrochloride Monohydrate + Spectinomycin Sulfate Tetrahydrate190
Lubabegron87
Melengestrol Acetate744
Monensin3,412
Monensin + Tylosin79
Monensin + Tylosin Phosphate69
Morantel Tartrate22
Moxidectin1,319
Novobiocin + Penicillin G Procaine22
Oxfendazole220
Oxytetracycline646
Oxytetracycline + Oxytetracycline Dihydrate76
Oxytetracycline Dihydrate88
Oxytetracycline Hydrochloride59
Oxytocin20
Pegbovigrastim90
Penicillin G Benzathine + Penicillin G Procaine50
Penicillin G Procaine202
Pirlimycin Hydrochloride23
Progesterone476
Ractopamine Hydrochloride180
Sulfadimethoxine64
Tildipirosin419
Tilmicosin180
Tilmicosin Phosphate827
Tulathromycin2,292
Tylosin180
Tylosin Phosphate148
Vitamin E255
Xylazine45
Zeranol163
Zilpaterol70

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Download all drugs for this species (CSV)

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 31,355 reports about cattle that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Death29.5%9,244 reports
  2. Lack of efficacy - NOS[the product did not have the expected effect]10.3%3,223 reports
  3. Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]8.6%2,697 reports
  4. Lack of efficacy (ectoparasite) - lice[the product did not have the expected effect: lice]7.4%2,308 reports
  5. Residues in milk4.7%1,466 reports
  6. Injection site swelling[swelling where the injection was given]3.8%1,181 reports
  7. Recumbency[lying down and unable or unwilling to rise]3.3%1,048 reports
  8. Anorexia[not eating]3.3%1,027 reports
  9. Anaphylaxis[sudden severe allergic-type reaction]3.3%1,020 reports
  10. Pruritus[itching]3.2%1,007 reports
  11. Diarrhoea[diarrhea]3%936 reports
  12. Alteration of milk quality2.7%860 reports
  13. Mastitis NOS[NOS: not otherwise specified]2.5%774 reports
  14. Alopecia NOS[hair loss, type not specified]2.4%751 reports
Show the next 16 signs
  1. Milk production decrease2.1%666 reports
  2. Death by euthanasia[the animal was euthanized]2.1%657 reports
  3. Ineffective, lice biting[legacy FDA term: the product did not have the expected effect (lice biting)]2.1%651 reports
  4. Collapse2.1%649 reports
  5. Lack of efficacy (protozoa) - Coccidia[the product did not have the expected effect: coccidia]2.1%644 reports
  6. Dyspnoea[difficulty breathing]2%642 reports
  7. Death-treatment failure2%624 reports
  8. Abortion1.9%586 reports
  9. Ineffective, estrus synchroniz[legacy FDA term: the product did not have the expected effect (estrus synchroniz)]1.8%578 reports
  10. PR-lung(s), lesion(s)[legacy FDA term: lesions found in the lungs]1.7%545 reports
  11. Ineffective, estrus suppressio[legacy FDA term: the product did not have the expected effect (estrus suppressio)]1.7%542 reports
  12. Depression[dull, quiet or withdrawn]1.7%538 reports
  13. Hypersalivation[drooling]1.7%537 reports
  14. Lameness1.6%490 reports
  15. Culture/titer data abnormal1.4%446 reports
  16. Lack of efficacy (lice)[the product did not have the expected effect: lice]1.4%445 reports

Download all signs (CSV)

Reports by month and by year

Reports about cattle for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports about cattle, by the year in which FDA received them
YearReports
2026249
2025662
2024705
2023725
2022685
2021774
2020955
2019982
20181,106
20171,275
20161,264
20151,130
20141,081
20131,229
20121,167
20111,065
20101,083
20091,002
2008991
20071,020
20061,041
20051,018
2004839
2003699
2002515
2001649
2000959
1999874
1998868
1997665
1996591
19951,511
1994460
1993188
1992198
1991162
1990159
1989410
1988192
1987207

What the reports record

Age of the animal

  • Under 1 year19.3%6,066
  • 1 to 3 years14.7%4,614
  • 4 to 7 years6.5%2,027
  • 8 to 11 years0.5%149
  • 12 years and over0.1%30
  • Age not given58.9%18,469

Weight of the animal

  • Under 5 kg (11 lb)under 0.1%4
  • 5 to 9.9 kg (11 to 22 lb)under 0.1%5
  • 10 to 24.9 kg (22 to 55 lb)0.1%23
  • 25 to 44.9 kg (55 to 99 lb)0.6%202
  • 45 kg and over (99 lb and over)53.5%16,783
  • Weight not given45.7%14,338

Outcome at the time of the report

  • Reports about cattle
  • All reports
  • Recovered/Normal7.2%2,256
  • Recovered with Sequela[recovered, with a lasting effect]1%317
  • Ongoing4.5%1,421
  • Died35.8%11,212
  • Euthanized1.7%527
  • Outcome Unknown23.8%7,447

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 31,355 reports about cattle.

Kind of report

  • Reports about cattle
  • All reports
  • Safety issue77%24,155
  • Lack of expected effectiveness20.4%6,389
  • Both safety and lack of expected effectiveness2%624
  • Manufacturing or product defect0.6%173
  • Otherunder 0.1%14

Each share of age, weight and kind is of the 31,355 reports about cattle. The thin bar is the same share in all 1,378,761 reports.

Ingredients, all combinations

The list has every active ingredient with 20 or more reports about cattle, in order of name. It has 75 ingredients.

Show the 75 ingredients

Breeds with a page

A breed has a page when 100 or more reports give that one breed. Reports about crossbred animals are in the species count only.

Cite this page

Pet Drug Reports. Cattle: adverse event reports for animal drugs. https://petdrugreports.com/species/cattle/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

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Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the cattle in the reports?

The figures are shares of the 31,355 reports about cattle received from January 1987 to June 2026. 19.3% give an age of under 1 year. 14.7% give an age of 1 to 3 years. 58.9% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 621 reports in the 12 months to June 2026. It received 668 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

What kinds of report are in the count?

Of the 31,355 reports received from January 1987 to June 2026, 77% are about a safety issue only. 22.4% are about a lack of expected effectiveness, alone or with a safety issue. 0.6% are about a defect of the product or its package.

Do more reports for cattle show a higher risk for cattle?

No. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices