Species
Rabbit: adverse event reports
511 reports, 0% of FDA's animal drug adverse event database
511 adverse event reports in FDA's database concern rabbits: 0% of all reports received from June 1987 to March 2026. 21 arrived in the 12 months to March 2026, up 200% from 7 in the 12 months before. That is 0% of all reports received in those 12 months and about 13 reports a year over the whole record.
By active ingredient, the drugs named most often are selamectin (19.6% of rabbit reports), meloxicam (15.1% of rabbit reports), ketamine hydrochloride (11.9% of rabbit reports) and isoflurane (8.6% of rabbit reports). Drugs given to the most animals lead the list for that reason; brands are masked in the public data.
The terms listed most often are death (35.8%), anorexia (10%) and weight loss (6.8%). 69.1% of reports stating seriousness were classed as serious (38.6% across all species), and 43.8% record a death or euthanasia (6.4% overall).
FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.
Drugs named most often, by active ingredient
| Active ingredients recorded for the drug | Reports | Share of rabbit reports | Share of the drug's reports that concern rabbits |
|---|---|---|---|
| Selamectin | 100 | 19.6% | 0.2% |
| Meloxicam | 77 | 15.1% | 0.4% |
| Ketamine Hydrochloride | 61 | 11.9% | 0.8% |
| Isoflurane | 44 | 8.6% | 0.9% |
| Imidacloprid + Moxidectin | 38 | 7.4% | 0.2% |
| Midazolam | 36 | 7% | 1.8% |
| Enrofloxacin | 34 | 6.7% | 0.4% |
| Buprenorphine | 31 | 6.1% | 0.4% |
| Ivermectin | 31 | 6.1% | 0.2% |
| Alfaxalone | 22 | 4.3% | 2.2% |
| Dexmedetomidine hydrochloride | 15 | 2.9% | 0.3% |
| Tilmicosin Phosphate | 12 | 2.3% | 0.3% |
| Amoxicillin | 10 | 2% | 0.1% |
| Carprofen | 9 | 1.8% | 0% |
| Sevoflurane | 9 | 1.8% | 0.7% |
| Hydromorphone | 8 | 1.6% | 0.6% |
| Sodium Chloride | 8 | 1.6% | 0.2% |
| Dexmedetomidine | 7 | 1.4% | 0.3% |
| Enrofloxacin + Silver sulfadiazine | 7 | 1.4% | 1% |
| Butorphanol Tartrate | 6 | 1.2% | 0.1% |
| Fluralaner | 6 | 1.2% | 0% |
| Maropitant | 6 | 1.2% | 0% |
| Monensin | 6 | 1.2% | 0.1% |
| Acepromazine Maleate | 5 | 1% | 0.2% |
| Atipamezole Hydrochloride | 5 | 1% | 0.1% |
| Sulfadimethoxine | 5 | 1% | 0.3% |
| Tylosin | 5 | 1% | 0.4% |
| Xylazine | 5 | 1% | 0.4% |
| Albendazole | 4 | 0.8% | 0.5% |
| Lidocaine | 4 | 0.8% | 0.8% |
Ordered by report count, which follows how widely a drug is used. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another". openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.
Signs listed in reports
share of rabbit reports listing the termall species
- Death35.8%183
- Anorexia[not eating]10%51
- Weight loss6.8%35
- Depression[dull, quiet or withdrawn]5.7%29
- Inappetence[reduced appetite]5.5%28
- Lethargy[unusually tired or inactive]5.5%28
- Cardiac arrest5.3%27
- Death by euthanasia[the animal was euthanized]3.7%19
- Convulsion[seizure]3.1%16
- Lack of efficacy - NOS[the product did not have the expected effect]3.1%16
- Apnoea[breathing stopped]2.9%15
- Diarrhoea[diarrhea]2.7%14
- Ataxia[unsteady, uncoordinated movement]2.5%13
- Ineffective, anesthesia[legacy FDA term: the product did not have the expected effect (anesthesia)]2.5%13
- Seizure NOS[seizure, type not specified]2.5%13
- Behavioural disorder NOS[behaviour change, type not specified]2.3%12
- Bradycardia[slow heart rate]2.3%12
- Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]2.3%12
- Head tilt - ear disorder2.2%11
- Tachypnoea[fast breathing]2%10
- Application site alopecia[hair loss where the product was applied]1.8%9
- Fever1.8%9
- Trembling1.8%9
- Hypothermia[low body temperature]1.6%8
- Skin oedema1.6%8
- Stillbirth1.6%8
- Weakness1.6%8
- Adipsia[not drinking]1.4%7
- Alopecia NOS[hair loss, type not specified]1.4%7
Single ingredients, pooled across combinations
- Selamectin103 reports · 20.2%
- Meloxicam77 reports · 15.1%
- Ketamine Hydrochloride61 reports · 11.9%
- Isoflurane44 reports · 8.6%
- Enrofloxacin41 reports · 8%
- Imidacloprid39 reports · 7.6%
- Moxidectin38 reports · 7.4%
- Midazolam36 reports · 7%
- Ivermectin33 reports · 6.5%
- Buprenorphine31 reports · 6.1%
- Alfaxalone22 reports · 4.3%
- Dexmedetomidine hydrochloride15 reports · 2.9%
- Tilmicosin Phosphate12 reports · 2.3%
- Amoxicillin11 reports · 2.2%
- Carprofen9 reports · 1.8%
- Sevoflurane9 reports · 1.8%
Age and weight
Age of the animal
Weight of the animal
Outcomes and report types
Outcome recorded in the report
What kind of report it was
Coloured bar: rabbit reports. Grey bar: all 1,357,245 reports. Outcomes are as stated by the reporter.
Trend
Reports by month FDA received them. The newest months are incomplete because FDA posts reports with a delay of three to six months.
| Measure | Rabbit | All reports |
|---|---|---|
| Reports | 511 | 1,357,245 |
| Classed serious, of reports stating it | 69.1% | 38.6% |
| Death or euthanasia recorded, per 1,000 reports | 438.4 | 63.8 |
| Filed as lack of expected effectiveness (wholly or partly) | 7.2% | 23% |
Questions about rabbit reports
How many adverse event reports involve rabbits?
511 reports through March 2026, 0% of the database; 21 in the latest 12 months.
Which drugs are reported most often for rabbits?
By active ingredient: selamectin (100), meloxicam (77), ketamine hydrochloride (61), isoflurane (44) and imidacloprid + moxidectin (38). The order tracks how widely each is used; brands are masked in the public data.
What signs are reported most in rabbits?
death (35.8%), anorexia (10%), weight loss (6.8%), depression (5.7%) and inappetence (5.5%).
What ages are the rabbits in these reports?
1 to 3 years (26.2%), under 1 year (18.4%) and 4 to 7 years (13.5%); age is not given in 35% of reports.
Do more reports mean more risk for this species?
No. Counts follow how many animals are treated and how readily their owners and veterinarians report. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."
How do I report a problem?
Call the drug company using the number on the label, or send Form FDA 1932a to FDA. See the guide on how to report.
Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.