Pet Drug Reports

Seal, Abnormalin adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: a product quality report, not a sign in an animal.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From July 1996 to June 2026, FDA received 5,608 adverse event reports for animal drugs that list this sign. That is 0.4% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 156 reports that list this sign.

Of the 5,608 reports, 0.6% are about people who were exposed to the drug. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 117 of 1,149 clinical signs with a page. Reports that list this sign rose by 10.6% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about people who were exposed to the drug are 0.6% of the reports that list this sign, and 1.2% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 46 drug pages.

Show the 46 drug pages
Drug pages with 20 or more reports that list this sign, in order of name
Active ingredientsReports that list the sign
Afoxolaner49
Altrenogest41
Amoxicillin282
Amoxicillin + Clavulanate Potassium44
Amoxicillin Trihydrate + Clavulanate Potassium150
Butorphanol Tartrate43
Carprofen276
Clindamycin Hydrochloride93
Clorsulon + Ivermectin99
Copper Naphthenate88
Cyclosporine43
Deracoxib41
Dexamethasone + Neomycin Sulfate + Thiabendazole31
Dirlotapide28
Doramectin92
Enrofloxacin96
Eprinomectin25
Etodolac22
Firocoxib22
Florfenicol20
Florfenicol + Mometasone furoate + Terbinafine32
Fluralaner96
Gonadorelin20
Grapiprant47
Hyaluronate Sodium25
Imidacloprid + Moxidectin28
Insulin85
Ivermectin97
Ivermectin + Pyrantel Pamoate730
Ketamine Hydrochloride63
Meloxicam480
Milbemycin Oxime55
Moxidectin737
Oclacitinib24
Orbifloxacin20
Oxytetracycline20
Oxytetracycline Hydrochloride25
Pimobendan48
Praziquantel25
Pyrantel Pamoate22
Pyrantel Tartrate89
Selamectin182
Sodium Chloride21
Sulfadimethoxine35
Triamcinolone Acetonide23
Tulathromycin25

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 51 ingredients.

Show the 51 ingredients

Reports by species

The share is of the 5,608 reports that list this sign. The sign is in 0.2% of all reports about the species human exposure. The sign is in 0% of all reports about the species dog.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Seal, Abnormal, by the year in which FDA received them
YearReports
202670
2025162
2024124
2023228
2022225
2021163
2020189
2019237
2018202
2017139
2016128
2015196
2014165
2013131
2012197
2011166
2010371
2009558
2008223
2007175
2006202
2005261
2004220
2003185
2002189
2001148
200087
199976
1998185
19975
19961

What these reports record

Outcome at the time of the report

  • Reports with this sign
  • All reports
  • Recovered/Normal0.4%20
  • Recovered with Sequela[recovered, with a lasting effect]0%0
  • Ongoingunder 0.1%2
  • Died0.1%4
  • Euthanized0%0
  • Outcome Unknown0.3%15

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 5,608 reports that list this sign.

Age of the animal

  • Reports with this sign
  • All reports
  • Under 1 yearunder 0.1%2
  • 1 to 3 years0.1%5
  • 4 to 7 years0.1%5
  • 8 to 11 years0.1%7
  • 12 years and over0.3%18
  • Age not given99.3%5,571

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Seal, Abnormal: adverse event reports for animal drugs. https://petdrugreports.com/reaction/seal-abnormal/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?

In plain words: a product quality report, not a sign in an animal. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 156 reports in the 12 months to June 2026. It received 141 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

How many of these reports have a serious flag?

Of the 36 reports that say if the event was serious, 11.1% have the serious flag. The person who sends a report sets the flag.

Does a drug in the table cause this sign?

The reports do not show that. A report can name more than one drug. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices