May 2024: adverse event reports received

7,698 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

7,698reports received

6,258same month a year earlier+23%

5,999monthly average, preceding 12 months

72%concern dogscats 16.6%

FDA's database holds 7,698 adverse event reports received in May 2024, against 6,258 in the same month a year earlier and a monthly average of 5,999 over the preceding 12 months.

72% of the month's reports concern dogs, 16.6% cats and 1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were pyrantel pamoate + sarolaner (1,117), bedinvetmab (846) and fluralaner (732), and the terms listed most often were vomiting (967), lethargy (624) and diarrhoea (483). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Pyrantel Pamoate + Sarolaner	1,117	14.5%
Bedinvetmab	846	11%
Fluralaner	732	9.5%
Ivermectin + Pyrantel Pamoate	572	7.4%
Afoxolaner	480	6.2%
Moxidectin	399	5.2%
Afoxolaner + Moxidectin + Pyrantel Pamoate	348	4.5%
Milbemycin Oxime + Praziquantel	293	3.8%
Frunevetmab	240	3.1%
Oclacitinib	212	2.8%
Gabapentin	202	2.6%
Nitenpyram	178	2.3%
Carprofen	165	2.1%
Velagliflozin	165	2.1%
Lotilaner	164	2.1%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting12.6%967
Lethargy[unusually tired or inactive]8.1%624
Diarrhoea[diarrhea]6.3%483
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.1%468
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]5.5%426
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.8%372
Seizure NOS[seizure, type not specified]4.3%332
Lack of efficacy - NOS[the product did not have the expected effect]4.3%330
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]4.2%327
Death3.1%242
Not eating3.1%241
Death by euthanasia[the animal was euthanized]3%229
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]2.9%226
Emesis (multiple)[vomiting more than once]2.8%218
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.5%195

Single ingredients, pooled

Pyrantel Pamoate27.4%2,109

Sarolaner18.1%1,392

Moxidectin11.7%902

Bedinvetmab11%846

Afoxolaner10.5%806

Fluralaner10.5%805

Praziquantel7.9%608

Ivermectin7.8%604

Milbemycin Oxime6.9%531

Frunevetmab3.1%240

Oclacitinib2.8%212

Selamectin2.7%207

Species

Dog72%5,543

Cat16.6%1,280

Horse1%75

Other or not given10.4%800

Questions about May 2024

How many animal drug adverse event reports did FDA receive in May 2024?

7,698 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 6,258.

Which drugs were named most often?

By active ingredient: pyrantel pamoate + sarolaner (1,117), bedinvetmab (846), fluralaner (732), ivermectin + pyrantel pamoate (572) and afoxolaner (480). Brands are masked in the public data.

Which signs were listed most often?

vomiting (967), lethargy (624), diarrhoea (483), lack of efficacy (ectoparasite) - flea (468) and lack of efficacy (endoparasite) - heartworm (426).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.