May 2022: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 5,636 adverse event reports for animal drugs in May 2022. It received 5,892 reports in May 2021. The average of the 12 months before May 2022 is 5,028 reports for each month.

Of the 5,636 reports, 79.6% are about dogs, 7.8% are about cats and 1.2% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Nov 2020 to Nov 2022. The column with the outline is May 2022.

Reports by species

Dog79.6%4,485
Cat7.8%437
Horse1.2%68
Other species, or species not given11.5%646

Drug pages with reports received in May 2022

The table has every drug page with 10 or more reports that FDA received in May 2022, in order of name. No count decides which drug is in the table. The table has 65 drug pages.

Show the 65 drug pages

Drug pages with 10 or more reports received in May 2022, in order of name
Active ingredients	Reports received in May 2022
(S) - methoprene	20
Afoxolaner	428
Amoxicillin Trihydrate + Clavulanate Potassium	12
Buprenorphine	13
Butorphanol Tartrate	34
Capromorelin	36
Carprofen	73
Cefovecin sodium	39
Cefpodoxime proxetil	10
Ceftiofur Crystalline Free Acid	16
Cephalexin	10
Cyclosporine	39
Dexamethasone	13
Dexmedetomidine	26
Dexmedetomidine hydrochloride	18
Doxycycline	30
Emodepside + Praziquantel	18
Enalapril Maleate	10
Enrofloxacin	12
Famotidine	12
Febantel + Praziquantel + Pyrantel Pamoate	21
Firocoxib	20
Florfenicol + Mometasone furoate + Terbinafine	44
Fluoxetine hydrochloride	11
Fluralaner	671
Fluralaner + Moxidectin	53
Gabapentin	48
Grapiprant	78
Imidacloprid	61
Imidacloprid + Moxidectin	60
Insulin	58
Ivermectin	26
Ivermectin + Praziquantel + Pyrantel Pamoate	19
Ivermectin + Pyrantel Pamoate	724
Lotilaner	136
Lufenuron + Milbemycin Oxime	75
Lufenuron + Milbemycin Oxime + Praziquantel	87
Maropitant	62
Melarsomine Dihydrochloride	82
Meloxicam	20
Metronidazole	14
Milbemycin Oxime	47
Milbemycin Oxime + Praziquantel	297
Milbemycin Oxime + Spinosad	208
Mirtazapine	15
Moxidectin	433
Nitenpyram	78
Oclacitinib	120
Omeprazole	27
Pimobendan	31
Polysulfated Glycosaminoglycan	36
Praziquantel	23
Praziquantel + Pyrantel Pamoate	22
Prednisolone	14
Prednisone	55
Propofol	16
Pyrantel Pamoate + Sarolaner	878
Sarolaner	113
Sarolaner + Selamectin	132
Selamectin	102
Sodium Chloride	62
Spinosad	32
Tigilanol tiglate	37
Tiletamine Hydrochloride + Zolazepam Hydrochloride	10
Trilostane	86

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 5,636 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting16.2%915 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]10.7%602 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]8.1%454 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]8%450 reports
Lethargy[unusually tired or inactive]7.9%447 reports
Diarrhoea[diarrhea]5.6%317 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]4.9%278 reports
Seizure NOS[seizure, type not specified]4.7%266 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]4%225 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.8%157 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.5%141 reports
Emesis (multiple)[vomiting more than once]2.4%133 reports
Anorexia[not eating]2.3%132 reports
Behavioural disorder NOS[behaviour change, type not specified]2.3%127 reports

Show the next 1 signs

Death2.3%127 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in May 2022, in order of name. It has 64 ingredients.

Show the 64 ingredients

The same month in other years

Cite this page

Pet Drug Reports. May 2022: adverse event reports for animal drugs. https://petdrugreports.com/month/2022-05/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for May 2022 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 915 reports of the 5,636 reports of May 2022 (16.2%).