May 2006: adverse event reports received

1,801 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,801reports received

1,897same month a year earlier-5%

1,659monthly average, preceding 12 months

71.1%concern dogscats 7.3%

FDA's database holds 1,801 adverse event reports received in May 2006, against 1,897 in the same month a year earlier and a monthly average of 1,659 over the preceding 12 months.

71.1% of the month's reports concern dogs, 7.3% cats and 3.1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were ivermectin + pyrantel pamoate (260), carprofen (164) and selamectin (139), and the terms listed most often were ineffective, heartworm larvae (319), vomiting (248) and depression (212). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Ivermectin + Pyrantel Pamoate	260	14.4%
Carprofen	164	9.1%
Selamectin	139	7.7%
Milbemycin Oxime	122	6.8%
Melarsomine Dihydrochloride	93	5.2%
Cyclosporine	92	5.1%
Deracoxib	90	5%
Lufenuron + Milbemycin Oxime	71	3.9%
Firocoxib	64	3.6%
Meloxicam	44	2.4%
Ivermectin	36	2%
Amoxicillin	33	1.8%
Ketamine Hydrochloride	25	1.4%
Nitenpyram	25	1.4%
Medetomidine	23	1.3%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]17.7%319
Vomiting13.8%248
Depression[dull, quiet or withdrawn]11.8%212
Anorexia[not eating]10.3%185
Death8.7%156
Diarrhoea[diarrhea]6.3%113
Accidental exposure[exposure that was not intended]5.2%93
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]4.7%85
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.2%76
Death by euthanasia[the animal was euthanized]3.8%69
Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]3.6%64
Ataxia[unsteady, uncoordinated movement]3.3%59
Convulsion[seizure]3.2%57
Elevated creatinine[a kidney value above the normal range]3.1%56
Fever3.1%55

Single ingredients, pooled

Ivermectin18.1%326

Pyrantel Pamoate15.4%277

Milbemycin Oxime10.7%193

Carprofen9.1%164

Selamectin7.7%139

Melarsomine Dihydrochloride5.2%93

Cyclosporine5.1%92

Deracoxib5%90

Lufenuron4.3%78

Firocoxib3.6%64

Meloxicam2.4%44

Amoxicillin1.8%33

Species

Dog71.1%1,280

Cat7.3%131

Horse3.1%55

Other or not given18.6%335

Questions about May 2006

How many animal drug adverse event reports did FDA receive in May 2006?

1,801 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,897.

Which drugs were named most often?

By active ingredient: ivermectin + pyrantel pamoate (260), carprofen (164), selamectin (139), milbemycin oxime (122) and melarsomine dihydrochloride (93). Brands are masked in the public data.

Which signs were listed most often?

ineffective, heartworm larvae (319), vomiting (248), depression (212), anorexia (185) and death (156).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.