May 2010: adverse event reports received

3,815 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

3,815reports received

3,453same month a year earlier+10%

3,348monthly average, preceding 12 months

77.3%concern dogscats 8.4%

FDA's database holds 3,815 adverse event reports received in May 2010, against 3,453 in the same month a year earlier and a monthly average of 3,348 over the preceding 12 months.

77.3% of the month's reports concern dogs, 8.4% cats and 1.5% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were spinosad (858), ivermectin + pyrantel pamoate (672) and milbemycin oxime (336), and the terms listed most often were vomiting (870), ineffective, heartworm larvae (594) and depression (437). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Spinosad	858	22.5%
Ivermectin + Pyrantel Pamoate	672	17.6%
Milbemycin Oxime	336	8.8%
Selamectin	274	7.2%
Lufenuron + Milbemycin Oxime	119	3.1%
Imidacloprid + Moxidectin	114	3%
Carprofen	109	2.9%
Melarsomine Dihydrochloride	98	2.6%
Meloxicam	86	2.3%
Cyclosporine	83	2.2%
Ivermectin + Praziquantel + Pyrantel Pamoate	63	1.7%
Firocoxib	55	1.4%
Maropitant	52	1.4%
Amoxicillin	51	1.3%
Insulin	49	1.3%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting22.8%870
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]15.6%594
Depression[dull, quiet or withdrawn]11.5%437
Anorexia[not eating]8.3%315
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.5%211
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]5.4%206
Diarrhoea[diarrhea]4.9%186
Accidental exposure[exposure that was not intended]4.5%173
Death3.6%138
Pruritus[itching]3.3%124
Convulsion[seizure]2.9%112
Ataxia[unsteady, uncoordinated movement]2.8%107
Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]2.6%100
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]1.9%74
Unpalatable[legacy FDA term: the animal would not take it]1.9%72

Single ingredients, pooled

Spinosad22.5%858

Pyrantel Pamoate20.7%789

Ivermectin20.5%782

Milbemycin Oxime11.9%455

Selamectin7.2%274

Praziquantel3.6%137

Moxidectin3.4%131

Lufenuron3.4%128

Imidacloprid3%114

Carprofen2.9%109

Melarsomine Dihydrochloride2.6%98

Meloxicam2.3%86

Species

Dog77.3%2,948

Cat8.4%322

Horse1.5%58

Other or not given12.8%487

Questions about May 2010

How many animal drug adverse event reports did FDA receive in May 2010?

3,815 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 3,453.

Which drugs were named most often?

By active ingredient: spinosad (858), ivermectin + pyrantel pamoate (672), milbemycin oxime (336), selamectin (274) and lufenuron + milbemycin oxime (119). Brands are masked in the public data.

Which signs were listed most often?

vomiting (870), ineffective, heartworm larvae (594), depression (437), anorexia (315) and lack of efficacy (endoparasite) - hookworm (211).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.