March 2024: adverse event reports received

6,461 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

6,461reports received

4,650same month a year earlier+39%

5,669monthly average, preceding 12 months

70.8%concern dogscats 16.4%

FDA's database holds 6,461 adverse event reports received in March 2024, against 4,650 in the same month a year earlier and a monthly average of 5,669 over the preceding 12 months.

70.8% of the month's reports concern dogs, 16.4% cats and 1.1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were bedinvetmab (868), pyrantel pamoate + sarolaner (850) and fluralaner (543), and the terms listed most often were vomiting (779), lethargy (540) and lack of efficacy (endoparasite) - heartworm (483). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Bedinvetmab	868	13.4%
Pyrantel Pamoate + Sarolaner	850	13.2%
Fluralaner	543	8.4%
Ivermectin + Pyrantel Pamoate	497	7.7%
Moxidectin	359	5.6%
Afoxolaner	300	4.6%
Milbemycin Oxime + Praziquantel	253	3.9%
Frunevetmab	231	3.6%
Afoxolaner + Moxidectin + Pyrantel Pamoate	221	3.4%
Gabapentin	216	3.3%
Oclacitinib	190	2.9%
Carprofen	188	2.9%
Velagliflozin	144	2.2%
Maropitant	137	2.1%
Bexagliflozin	125	1.9%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting12.1%779
Lethargy[unusually tired or inactive]8.4%540
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]7.5%483
Diarrhoea[diarrhea]6.6%424
Lack of efficacy - NOS[the product did not have the expected effect]5.5%355
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]4.6%297
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.1%266
Seizure NOS[seizure, type not specified]4.1%263
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]3.5%228
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.4%218
Death by euthanasia[the animal was euthanized]3.3%212
Not eating3%191
Death2.7%177
Emesis (multiple)[vomiting more than once]2.6%168
Anorexia[not eating]2.5%161

Single ingredients, pooled

Pyrantel Pamoate25.4%1,639

Sarolaner16.5%1,063

Bedinvetmab13.4%868

Moxidectin10.7%692

Fluralaner8.9%578

Ivermectin8.3%538

Praziquantel8.2%527

Afoxolaner8%516

Milbemycin Oxime7.5%487

Frunevetmab3.6%231

Gabapentin3.3%216

Oclacitinib2.9%190

Species

Dog70.8%4,574

Cat16.4%1,059

Horse1.1%70

Other or not given11.7%758

Questions about March 2024

How many animal drug adverse event reports did FDA receive in March 2024?

6,461 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 4,650.

Which drugs were named most often?

By active ingredient: bedinvetmab (868), pyrantel pamoate + sarolaner (850), fluralaner (543), ivermectin + pyrantel pamoate (497) and moxidectin (359). Brands are masked in the public data.

Which signs were listed most often?

vomiting (779), lethargy (540), lack of efficacy (endoparasite) - heartworm (483), diarrhoea (424) and lack of efficacy - NOS (355).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.