March 2001: adverse event reports received

1,240 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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1,240reports received

1,395same month a year earlier-11%

1,545monthly average, preceding 12 months

57.7%concern dogscats 15.3%

FDA's database holds 1,240 adverse event reports received in March 2001, against 1,395 in the same month a year earlier and a monthly average of 1,545 over the preceding 12 months.

57.7% of the month's reports concern dogs, 15.3% cats and 2.4% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were carprofen (297), selamectin (280) and doramectin (57), and the terms listed most often were accidental exposure (193), vomiting (143) and no sign (135). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Carprofen	297	24%
Selamectin	280	22.6%
Doramectin	57	4.6%
Etodolac	56	4.5%
Selegiline Hydrochloride	51	4.1%
Moxidectin	44	3.5%
(S) - methoprene	32	2.6%
Medetomidine	29	2.3%
Milbemycin Oxime	23	1.9%
Lufenuron + Milbemycin Oxime	19	1.5%
Tilmicosin Phosphate	18	1.5%
Amoxicillin	17	1.4%
Atipamezole Hydrochloride	17	1.4%
Enrofloxacin + Silver sulfadiazine	16	1.3%
Enrofloxacin	15	1.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Accidental exposure[exposure that was not intended]15.6%193
Vomiting11.5%143
No sign[no clinical sign was reported]10.9%135
Depression[dull, quiet or withdrawn]9.8%122
Anorexia[not eating]7.9%98
Death7.8%97
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]5%62
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]4.8%59
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.4%55
Diarrhoea[diarrhea]4.4%54
Lack of efficacy (ectoparasite) - lice[the product did not have the expected effect: lice]4.3%53
Death by euthanasia[the animal was euthanized]3.7%46
Ataxia[unsteady, uncoordinated movement]3.5%43
Unclassifiable adverse event[event that fits no dictionary term]3.4%42
Convulsion[seizure]3.2%40

Single ingredients, pooled

Carprofen24%297

Selamectin22.6%280

Doramectin4.6%57

Etodolac4.5%56

Selegiline Hydrochloride4.1%51

Moxidectin3.5%44

Milbemycin Oxime3.4%42

(S) - methoprene2.6%32

Enrofloxacin2.5%31

Medetomidine2.3%29

Lufenuron1.9%24

Tilmicosin Phosphate1.5%18

Species

Dog57.7%716

Cat15.3%190

Horse2.4%30

Other or not given24.5%304

Questions about March 2001

How many animal drug adverse event reports did FDA receive in March 2001?

1,240 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,395.

Which drugs were named most often?

By active ingredient: carprofen (297), selamectin (280), doramectin (57), etodolac (56) and selegiline hydrochloride (51). Brands are masked in the public data.

Which signs were listed most often?

accidental exposure (193), vomiting (143), no sign (135), depression (122) and anorexia (98).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.