March 2023: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 4,650 adverse event reports for animal drugs in March 2023. It received 5,292 reports in March 2022. The average of the 12 months before March 2023 is 5,013 reports for each month.

Of the 4,650 reports, 69.5% are about dogs, 15.7% are about cats and 1.1% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Sep 2021 to Sep 2023. The column with the outline is March 2023.

Reports by species

Dog69.5%3,231
Cat15.7%731
Horse1.1%51
Other species, or species not given13.7%637

Drug pages with reports received in March 2023

The table has every drug page with 10 or more reports that FDA received in March 2023, in order of name. No count decides which drug is in the table. The table has 75 drug pages.

Show the 75 drug pages

Drug pages with 10 or more reports received in March 2023, in order of name
Active ingredients	Reports received in March 2023
(S) - methoprene	15
Acepromazine Maleate	11
Afoxolaner	266
Amoxicillin Trihydrate + Clavulanate Potassium	17
Atipamezole Hydrochloride	14
Bupivacaine	11
Buprenorphine	115
Butorphanol Tartrate	45
Capromorelin	27
Carprofen	86
Cefovecin sodium	55
Clotrimazole + Gentamicin	15
Cyclosporine	34
Deracoxib	10
Dexmedetomidine	38
Dexmedetomidine hydrochloride	12
Diphenhydramine	15
Doxycycline	23
Emodepside + Praziquantel	29
Enrofloxacin	21
Famotidine	11
Febantel + Praziquantel + Pyrantel Pamoate	21
Firocoxib	18
Florfenicol + Mometasone furoate + Terbinafine	50
Flunixin	10
Fluoxetine hydrochloride	11
Fluralaner	345
Fluralaner + Moxidectin	45
Frunevetmab	235
Gabapentin	69
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	18
Grapiprant	47
Hydromorphone	10
Imidacloprid	46
Imidacloprid + Moxidectin	48
Insulin	70
Isoflurane	40
Ivermectin	30
Ivermectin + Pyrantel Pamoate	546
Ketamine Hydrochloride	22
Lotilaner	81
Lufenuron + Milbemycin Oxime	43
Lufenuron + Milbemycin Oxime + Praziquantel	58
Maropitant	91
Medetomidine hydrochloride + Vatinoxan hydrochloride	22
Melarsomine Dihydrochloride	47
Meloxicam	32
Methimazole	10
Metronidazole	17
Midazolam	18
Milbemycin Oxime	31
Milbemycin Oxime + Praziquantel	230
Milbemycin Oxime + Spinosad	128
Mirtazapine	21
Moxidectin	334
Nitenpyram	65
Oclacitinib	90
Omeprazole	20
Phenylpropanolamine hydrochloride	11
Pimobendan	59
Polysulfated Glycosaminoglycan	37
Praziquantel	28
Praziquantel + Pyrantel Pamoate	18
Prednisolone	27
Prednisone	33
Propofol	36
Pyrantel Pamoate	14
Pyrantel Pamoate + Sarolaner	783
Robenacoxib	38
Sarolaner	74
Sarolaner + Selamectin	84
Selamectin	65
Sodium Chloride	65
Tigilanol tiglate	34
Trilostane	69

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 4,650 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting13.2%613 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]11.5%534 reports
Lethargy[unusually tired or inactive]7.4%344 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.8%270 reports
Diarrhoea[diarrhea]5.7%263 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]4.2%196 reports
Seizure NOS[seizure, type not specified]3.9%180 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]3.6%169 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.6%167 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]3.3%154 reports
Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]3%140 reports
Death2.9%135 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.7%126 reports
Not eating2.7%125 reports

Show the next 1 signs

Containers, Damaged[a product quality report, not a sign in an animal]2.6%119 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in March 2023, in order of name. It has 81 ingredients.

Show the 81 ingredients

The same month in other years

Cite this page

Pet Drug Reports. March 2023: adverse event reports for animal drugs. https://petdrugreports.com/month/2023-03/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for March 2023 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 613 reports of the 4,650 reports of March 2023 (13.2%).