Panting: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From November 2004 to June 2026, FDA received 15,433 adverse event reports for animal drugs that list this sign. That is 1.1% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 1,143 reports that list this sign.

Of the 15,433 reports, 81.3% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 34 of 1,149 clinical signs with a page. Reports that list this sign fell by 17.8% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 81.3% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 114 drug pages.

Show the 114 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
(S) - methoprene	161
Acepromazine Maleate	74
Afoxolaner	1,436
Afoxolaner + Moxidectin + Pyrantel Pamoate	124
Alprazolam	21
Amantadine	28
Amlodipine	20
Amoxicillin	51
Amoxicillin + Clavulanate Potassium	61
Amoxicillin Trihydrate + Clavulanate Potassium	80
Atipamezole Hydrochloride	141
Atropine	37
Bedinvetmab	963
Benazepril	21
Buprenorphine	201
Butorphanol Tartrate	243
Capromorelin	63
Carprofen	749
Cefovecin sodium	192
Cefpodoxime proxetil	82
Cephalexin	68
Cetirizine	21
Clindamycin	33
Cyclosporine	254
Deracoxib	127
Desoxycorticosterone Pivalate	38
Dexamethasone	194
Dexamethasone Sodium Phosphate	61
Dexmedetomidine	81
Dexmedetomidine hydrochloride	128
Diazepam	32
Diphenhydramine	307
Doxycycline	151
Emodepside + Praziquantel	28
Enalapril Maleate	59
Enrofloxacin	107
Eprinomectin + Esafoxolaner + Praziquantel	29
Estriol	26
Famotidine	148
Febantel + Praziquantel + Pyrantel Pamoate	71
Fentanyl	43
Firocoxib	126
Florfenicol + Mometasone furoate + Terbinafine	91
Fluoxetine hydrochloride	97
Fluralaner	968
Fluralaner + Moxidectin	50
Frunevetmab	41
Furosemide	63
Gabapentin	566
Grapiprant	299
Hydrocodone	29
Hydromorphone	55
Hydroxyzine	30
Ilunocitinib	45
Imidacloprid	148
Imidacloprid + Moxidectin	325
Insulin	125
Isoflurane	136
Ivermectin	164
Ivermectin + Praziquantel + Pyrantel Pamoate	116
Ivermectin + Pyrantel Pamoate	790
Ketamine Hydrochloride	82
Ketoconazole	61
Levothyroxine sodium	184
Lidocaine	23
Lotilaner	248
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate	33
Lufenuron + Milbemycin Oxime	189
Lufenuron + Milbemycin Oxime + Praziquantel	43
Lufenuron + Praziquantel	33
Maropitant	507
Melarsomine Dihydrochloride	844
Meloxicam	165
Methadone	20
Methocarbamol	38
Methylprednisolone Acetate	23
Metoclopramide	35
Metronidazole	134
Midazolam	69
Milbemycin Oxime	102
Milbemycin Oxime + Praziquantel	298
Milbemycin Oxime + Spinosad	1,112
Mirtazapine	28
Moxidectin	940
Moxidectin + Pyrantel Pamoate + Sarolaner	27
Nitenpyram	2,113
Oclacitinib	528
Omeprazole	62
Ondansetron	43
Phenobarbital	43
Phenylpropanolamine hydrochloride	102
Pimobendan	159
Polysulfated Glycosaminoglycan	147
Praziquantel	28
Praziquantel + Pyrantel Pamoate	88
Prednisolone	64
Prednisolone + Trimeprazine Tartrate	47
Prednisone	460
Propofol	104
Pyrantel Pamoate	60
Pyrantel Pamoate + Sarolaner	433
Robenacoxib	51
Sarolaner	308
Sarolaner + Selamectin	86
Selamectin	197
Sevoflurane	26
Spinosad	470
Sucralfate	56
Tigilanol tiglate	137
Tramadol	215
Trazodone	98
Trilostane	570
Ursodiol	28
Vitamin E	23

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 111 ingredients.

Show the 111 ingredients

Reports by species

Dog81.3%12,550
Cat18.4%2,841
Cattle0.2%24
Horseunder 0.1%6
Otherunder 0.1%2
Sheepunder 0.1%2

The share is of the 15,433 reports that list this sign. The sign is in 1.3% of all reports about the species dog. The sign is in 1.9% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Panting, by the year in which FDA received them
Year	Reports
2026	522
2025	1,261
2024	1,480
2023	1,041
2022	867
2021	889
2020	1,018
2019	1,010
2018	992
2017	1,185
2016	1,127
2015	1,066
2014	1,037
2013	888
2012	782
2011	148
2010	18
2009	17
2008	47
2007	12
2006	6
2005	19
2004	1

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal34.5%5,321, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]1.8%276, All reports: 2.3%
Ongoing24.5%3,778, All reports: 17.4%
Died5.4%830, All reports: 4.9%
Euthanized5.2%806, All reports: 1.5%
Outcome Unknown28.8%4,439, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 15,433 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year6.4%982, All reports: 9.5%
1 to 3 years24.7%3,805, All reports: 23.9%
4 to 7 years25.4%3,917, All reports: 20.2%
8 to 11 years24.4%3,760, All reports: 15.4%
12 years and over15.8%2,431, All reports: 10.7%
Age not given3.5%538, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

Palpebral disorder NOS[NOS: not otherwise specified]
Pancreas disorder
Pancreatitis[inflamed pancreas]
Pancreatitis NOS[NOS: not otherwise specified]
Papilloma
Papule
Paraesthesia
Paralysis

All clinical signs

Cite this page

Pet Drug Reports. Panting: adverse event reports for animal drugs. https://petdrugreports.com/reaction/panting/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 1,143 reports in the 12 months to June 2026. It received 1,390 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 15,202 reports that say if the event was serious, 49.9% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices