Pet Drug Reports

Maine Coon: adverse event reports for animal drugs

Breed of cat

The FDA breed label is "Maine Coon". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From December 1989 to June 2026, FDA received 2,262 reports that give the breed Maine Coon. That is 1.5% of the reports about cats. In the 12 months to June 2026, FDA received 163 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 2,262 reports are "Vomiting", "Lethargy" and "Lack of efficacy (ectoparasite) - flea". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 5 of 21 breeds of cats with a page. Reports that give this breed fell by 17.3% in the 12 months to June 2026, compared with the 12 months before. Reports about cats fell by 10.5% in the same periods. The newest months can get more reports in a later update. The sign "Panting" is in 4.7% of the reports that give this breed, and in 1.9% of the reports about cats.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 73 drug pages.

Show the 73 drug pages
Drug pages with 5 or more reports that give the breed Maine Coon, in order of name
Active ingredientsReports that give this breed
(S) - methoprene6
Acepromazine Maleate5
Alfaxalone9
Amlodipine6
Amoxicillin23
Amoxicillin + Clavulanate Potassium8
Amoxicillin Trihydrate + Clavulanate Potassium15
Atipamezole Hydrochloride16
Bexagliflozin39
Bupivacaine7
Buprenorphine87
Butorphanol Tartrate32
Capromorelin13
Carprofen19
Cefovecin sodium118
Clindamycin5
Clindamycin Hydrochloride8
Cyclosporine64
Dexamethasone9
Dexamethasone + Neomycin Sulfate + Thiabendazole9
Dexmedetomidine24
Dexmedetomidine hydrochloride12
Diphenhydramine5
Emodepside + Praziquantel39
Enrofloxacin16
Enrofloxacin + Silver sulfadiazine5
Eprinomectin + Esafoxolaner + Praziquantel34
Eprinomectin + Praziquantel6
Famotidine9
Florfenicol + Mometasone furoate + Terbinafine10
Fluralaner188
Fluralaner + Moxidectin56
Frunevetmab108
Furosemide8
Gabapentin33
Imidacloprid30
Imidacloprid + Moxidectin131
Insulin70
Isoflurane33
Itraconazole10
Ivermectin14
Ketamine Hydrochloride24
Lotilaner21
Lufenuron15
Marbofloxacin11
Maropitant71
Medetomidine7
Meloxicam49
Methimazole18
Methylprednisolone Acetate13
Metronidazole6
Midazolam14
Milbemycin Oxime5
Mirtazapine31
Molidustat6
Nitenpyram213
Oclacitinib6
Orbifloxacin12
Polysulfated Glycosaminoglycan6
Pradofloxacin12
Praziquantel20
Praziquantel + Pyrantel Pamoate9
Prednisolone24
Prednisone13
Propofol29
Pyrantel Pamoate7
Robenacoxib60
Sarolaner + Selamectin121
Selamectin325
Sevoflurane5
Spinosad253
Tiletamine Hydrochloride + Zolazepam Hydrochloride8
Velagliflozin46

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 2,262 reports that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Vomiting13.2%298 reports
  2. Lethargy[unusually tired or inactive]11.3%255 reports
  3. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]8.5%193 reports
  4. Anorexia[not eating]7.7%175 reports
  5. Application site alopecia[hair loss where the product was applied]5.9%134 reports
  6. Diarrhoea[diarrhea]5.7%130 reports
  7. Application site hair loss[hair loss where the product was applied]5.2%118 reports
  8. Emesis[vomiting]5.2%118 reports
  9. Behavioural disorder NOS[behaviour change, type not specified]5.1%115 reports
  10. Panting4.7%106 reports
  11. Weight loss4.6%105 reports
  12. Lack of efficacy - NOS[the product did not have the expected effect]4.5%101 reports
  13. Hyperactivity4.4%99 reports
  14. Death4.2%94 reports
Show the next 11 signs
  1. Hypersalivation[drooling]3.8%86 reports
  2. Pruritus[itching]3.6%81 reports
  3. Death by euthanasia[the animal was euthanized]3.5%80 reports
  4. Vocalisation[crying out or unusual noise]3.5%79 reports
  5. Ataxia[unsteady, uncoordinated movement]3.4%78 reports
  6. Depression[dull, quiet or withdrawn]3.4%76 reports
  7. Not eating3.2%73 reports
  8. Fever2.8%64 reports
  9. Decreased appetite2.7%62 reports
  10. Agitation2.4%54 reports
  11. Hiding2.4%54 reports

What the reports record

Age of the animal

  • Maine Coon reports
  • All reports about cats
  • Under 1 year10.9%247, All reports about cats: 12.1%
  • 1 to 3 years22.6%511, All reports about cats: 19.7%
  • 4 to 7 years20.7%469, All reports about cats: 18.3%
  • 8 to 11 years20.5%464, All reports about cats: 17%
  • 12 years and over21.7%491, All reports about cats: 20%
  • Age not given3.5%80, All reports about cats: 12.8%

Weight of the animal

  • Maine Coon reports
  • All reports about cats
  • Under 5 kg (11 lb)31.3%709, All reports about cats: 50.3%
  • 5 to 9.9 kg (11 to 22 lb)59.9%1,355, All reports about cats: 34.1%
  • 10 to 24.9 kg (22 to 55 lb)4%91, All reports about cats: 0.5%
  • 25 to 44.9 kg (55 to 99 lb)0%0, All reports about cats: 0%
  • 45 kg and over (99 lb and over)0%0, All reports about cats: 0%
  • Weight not given4.7%107, All reports about cats: 15%

Outcome at the time of the report

  • Recovered/Normal24.7%558
  • Recovered with Sequela[recovered, with a lasting effect]0.8%17
  • Ongoing27.1%614
  • Died5.7%128
  • Euthanized2.5%56
  • Outcome Unknown23.3%526

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 2,262 reports that give this breed.

Each share of age and weight is of the 2,262 reports that give this breed. The thin bar is the same share in the 151,153 reports about cats.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Maine Coon, by the year in which FDA received them
YearReports
202681
2025173
2024191
2023165
202281
202193
2020105
2019121
2018125
2017134
2016107
2015117
2014131
2013122
2012100
201163
201078
200957
200833
200735
200624
200520
200418
20036
200217
200120
200024
19995
19988
19974
19961
19941
19931
19891

Next in the A to Z list of breeds

All reports about cats. All breeds

Cite this page

Pet Drug Reports. Maine Coon: adverse event reports for animal drugs. https://petdrugreports.com/breed/cat/maine-coon/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?

The figures are shares of the 2,262 reports about this breed received from December 1989 to June 2026. 22.6% give an age of 1 to 3 years. 21.7% give an age of 12 years and over. 3.5% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 163 reports in the 12 months to June 2026. It received 197 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Why are crossbred animals not in the count?

The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for cats.

Do the reports show that this breed reacts more to a drug?

No. The reports do not give the number of animals of the breed. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices