Pet Drug Reports

Manx: adverse event reports for animal drugs

Breed of cat

The FDA breed label is "Manx". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From December 1988 to May 2026, FDA received 328 reports that give the breed Manx. That is 0.2% of the reports about cats. In the 12 months to June 2026, FDA received 19 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 328 reports are "Vomiting", "Lethargy" and "Anorexia". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 12 of 21 breeds of cats with a page. Fewer than 20 reports gave this breed in the 12 months before June 2026, so this page gives no change. The sign "Depression" is in 8.5% of the reports that give this breed, and in 4.1% of the reports about cats.

Search engines list a breed page with 1,500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 19 drug pages.

Drug pages with 5 or more reports that give the breed Manx, in order of name
Active ingredientsReports that give this breed
Bexagliflozin5
Buprenorphine7
Cefovecin sodium28
Emodepside + Praziquantel7
Eprinomectin + Esafoxolaner + Praziquantel6
Fluralaner25
Fluralaner + Moxidectin5
Frunevetmab24
Gabapentin5
Imidacloprid + Moxidectin24
Insulin10
Maropitant10
Meloxicam10
Mirtazapine5
Nitenpyram15
Robenacoxib9
Sarolaner + Selamectin19
Selamectin58
Spinosad39

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 328 reports that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Vomiting16.2%53 reports
  2. Lethargy[unusually tired or inactive]12.8%42 reports
  3. Anorexia[not eating]10.4%34 reports
  4. Depression[dull, quiet or withdrawn]8.5%28 reports
  5. Death8.2%27 reports
  6. Application site alopecia[hair loss where the product was applied]7.3%24 reports
  7. Emesis[vomiting]7.3%24 reports
  8. Diarrhoea[diarrhea]6.7%22 reports
  9. Weight loss6.4%21 reports
  10. Death by euthanasia[the animal was euthanized]6.1%20 reports
  11. Application site hair loss[hair loss where the product was applied]5.8%19 reports
  12. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]5.8%19 reports
  13. Hypersalivation[drooling]4.9%16 reports
  14. Lack of efficacy - NOS[the product did not have the expected effect]4.6%15 reports
Show the next 11 signs
  1. Ataxia[unsteady, uncoordinated movement]4.3%14 reports
  2. Dehydration4.3%14 reports
  3. Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]4%13 reports
  4. Not eating4%13 reports
  5. Anaemia NOS[low red blood cell count]3.7%12 reports
  6. Pruritus[itching]3.7%12 reports
  7. Adipsia[not drinking]3.4%11 reports
  8. Behavioural disorder NOS[behaviour change, type not specified]3.4%11 reports
  9. Fever3%10 reports
  10. Hyperglycaemia[high blood sugar]2.7%9 reports
  11. Hypothermia[low body temperature]2.7%9 reports

What the reports record

Age of the animal

  • Manx reports
  • All reports about cats
  • Under 1 year12.5%41, All reports about cats: 12.1%
  • 1 to 3 years19.8%65, All reports about cats: 19.7%
  • 4 to 7 years21.6%71, All reports about cats: 18.3%
  • 8 to 11 years19.2%63, All reports about cats: 17%
  • 12 years and over24.7%81, All reports about cats: 20%
  • Age not given2.1%7, All reports about cats: 12.8%

Weight of the animal

  • Manx reports
  • All reports about cats
  • Under 5 kg (11 lb)54.3%178, All reports about cats: 50.3%
  • 5 to 9.9 kg (11 to 22 lb)36.6%120, All reports about cats: 34.1%
  • 10 to 24.9 kg (22 to 55 lb)0.9%3, All reports about cats: 0.5%
  • 25 to 44.9 kg (55 to 99 lb)0%0, All reports about cats: 0%
  • 45 kg and over (99 lb and over)0%0, All reports about cats: 0%
  • Weight not given8.2%27, All reports about cats: 15%

Outcome at the time of the report

  • Recovered/Normal18.6%61
  • Recovered with Sequela[recovered, with a lasting effect]0.6%2
  • Ongoing26.8%88
  • Died10.4%34
  • Euthanized4%13
  • Outcome Unknown18.6%61

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 328 reports that give this breed.

Each share of age and weight is of the 328 reports that give this breed. The thin bar is the same share in the 151,153 reports about cats.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Manx, by the year in which FDA received them
YearReports
202612
202514
202424
202320
202212
202116
202010
201920
201812
201722
201614
201510
201419
201315
201217
20117
201013
20097
200811
20077
200610
20057
20042
20032
20023
20014
20004
19992
19982
19971
19962
19942
19932
19922
19881

Next in the A to Z list of breeds

All reports about cats. All breeds

Cite this page

Pet Drug Reports. Manx: adverse event reports for animal drugs. https://petdrugreports.com/breed/cat/manx/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?

The figures are shares of the 328 reports about this breed received from December 1988 to May 2026. 24.7% give an age of 12 years and over. 21.6% give an age of 4 to 7 years. 2.1% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 19 reports in the 12 months to June 2026. It received 16 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Why are crossbred animals not in the count?

The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for cats.

Do the reports show that this breed reacts more to a drug?

No. The reports do not give the number of animals of the breed. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices