Pet Drug Reports

Domestic Longhair: adverse event reports for animal drugs

Breed of cat

The FDA breed label is "Domestic Longhair". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From May 2002 to June 2026, FDA received 9,747 reports that give the breed Domestic Longhair. That is 6.5% of the reports about cats. In the 12 months to June 2026, FDA received 1,026 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 9,747 reports are "Lethargy", "Vomiting" and "Lack of efficacy (ectoparasite) - flea". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 2 of 21 breeds of cats with a page. Reports that give this breed rose by 7.0% in the 12 months to June 2026, compared with the 12 months before. Reports about cats fell by 10.5% in the same periods. The newest months can get more reports in a later update. The sign "Lethargy" is in 13.6% of the reports that give this breed, and in 9.7% of the reports about cats.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 119 drug pages.

Show the 119 drug pages
Drug pages with 5 or more reports that give the breed Domestic Longhair, in order of name
Active ingredientsReports that give this breed
(S) - methoprene53
Acepromazine Maleate30
Afoxolaner6
Alfaxalone42
Amlodipine28
Amoxicillin31
Amoxicillin + Clavulanate Potassium52
Amoxicillin Trihydrate + Clavulanate Potassium65
Ampicillin Sodium8
Atipamezole Hydrochloride75
Atropine16
Azithromycin6
Betamethasone Acetate + Florfenicol + Terbinafine12
Bexagliflozin331
Bupivacaine23
Buprenorphine392
Butorphanol Tartrate158
Butorphanol Tartrate + Dexmedetomidine + Ketamine Hydrochloride11
Capromorelin67
Carprofen6
Cefovecin sodium607
Cefpodoxime proxetil6
Cephalexin9
Cetirizine5
Chlorambucil7
Cisapride8
Clindamycin23
Cyclosporine184
Dexamethasone61
Dexamethasone + Neomycin Sulfate + Thiabendazole48
Dexamethasone + Thiabendazole7
Dexamethasone Sodium Phosphate10
Dexmedetomidine100
Dexmedetomidine hydrochloride92
Diazepam14
Diazepam + Ketamine Hydrochloride5
Diphenhydramine34
Doxycycline27
Emodepside + Praziquantel349
Enrofloxacin61
Enrofloxacin + Silver sulfadiazine5
Eprinomectin + Esafoxolaner + Praziquantel230
Eprinomectin + Praziquantel39
Epsiprantel6
Famotidine17
Fentanyl8
Florfenicol + Mometasone furoate + Terbinafine45
Florfenicol + Terbinafine8
Fluoxetine hydrochloride8
Fluralaner1,000
Fluralaner + Moxidectin274
Frunevetmab733
Furosemide19
Gabapentin180
Glycopyrrolate8
Hydromorphone22
Imidacloprid172
Imidacloprid + Moxidectin615
Insulin253
Insulin Glargine5
Isoflurane144
Itraconazole26
Ivermectin16
Ketamine Hydrochloride160
Ketoconazole8
Lactulose14
Lidocaine20
Lotilaner75
Lufenuron20
Marbofloxacin21
Maropitant270
Meloxicam111
Methadone13
Methimazole107
Methocarbamol5
Methylprednisolone9
Methylprednisolone Acetate77
Metoclopramide9
Metronidazole31
Midazolam68
Milbemycin Oxime23
Milbemycin Oxime + Spinosad22
Mirtazapine172
Molidustat48
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide11
Nitenpyram1,031
Oclacitinib31
Ondansetron22
Orbifloxacin35
Pentobarbital Sodium + Phenytoin Sodium5
Phenobarbital12
Pimobendan6
Polysulfated Glycosaminoglycan20
Pradofloxacin51
Praziquantel121
Praziquantel + Pyrantel Pamoate78
Prednisolone110
Prednisone74
Pregabalin12
Propofol84
Pyrantel Pamoate21
Robenacoxib225
Sarolaner14
Sarolaner + Selamectin498
Selamectin820
Sevoflurane24
Silver sulfadiazine5
Sodium Chloride12
Spinosad1,198
Sucralfate5
Sulfadimethoxine7
Telmisartan24
Tiletamine Hydrochloride25
Tiletamine Hydrochloride + Zolazepam Hydrochloride18
Triamcinolone5
Triamcinolone Acetonide7
Velagliflozin421
Vitamin E5
Xylazine6

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 9,747 reports that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Lethargy[unusually tired or inactive]13.6%1,330 reports
  2. Vomiting12%1,174 reports
  3. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]10.5%1,019 reports
  4. Lack of efficacy - NOS[the product did not have the expected effect]6.1%596 reports
  5. Behavioural disorder NOS[behaviour change, type not specified]5.9%575 reports
  6. Emesis[vomiting]5.8%568 reports
  7. Weight loss5.7%560 reports
  8. Anorexia[not eating]5.5%540 reports
  9. Application site hair loss[hair loss where the product was applied]5.3%518 reports
  10. Diarrhoea[diarrhea]5.2%508 reports
  11. Panting5.2%502 reports
  12. Hyperactivity4.4%431 reports
  13. Vocalisation[crying out or unusual noise]4.4%424 reports
  14. Not eating4.2%405 reports
Show the next 11 signs
  1. Application site alopecia[hair loss where the product was applied]3.7%365 reports
  2. Ataxia[unsteady, uncoordinated movement]3.5%346 reports
  3. Death3.5%339 reports
  4. Agitation3.3%326 reports
  5. Decreased appetite3.3%323 reports
  6. Hiding3.3%322 reports
  7. Ketosis[ketones building up in the body]3%293 reports
  8. Pruritus[itching]3%292 reports
  9. Death by euthanasia[the animal was euthanized]3%291 reports
  10. Hypersalivation[drooling]3%289 reports
  11. Other abnormal test result NOS[abnormal laboratory result, type not specified]2.5%243 reports

What the reports record

Age of the animal

  • Domestic Longhair reports
  • All reports about cats
  • Under 1 year8.6%843, All reports about cats: 12.1%
  • 1 to 3 years20.4%1,992, All reports about cats: 19.7%
  • 4 to 7 years21.1%2,059, All reports about cats: 18.3%
  • 8 to 11 years20.5%2,000, All reports about cats: 17%
  • 12 years and over26.8%2,609, All reports about cats: 20%
  • Age not given2.5%244, All reports about cats: 12.8%

Weight of the animal

  • Domestic Longhair reports
  • All reports about cats
  • Under 5 kg (11 lb)53.5%5,217, All reports about cats: 50.3%
  • 5 to 9.9 kg (11 to 22 lb)41.4%4,033, All reports about cats: 34.1%
  • 10 to 24.9 kg (22 to 55 lb)0.7%68, All reports about cats: 0.5%
  • 25 to 44.9 kg (55 to 99 lb)under 0.1%2, All reports about cats: 0%
  • 45 kg and over (99 lb and over)under 0.1%1, All reports about cats: 0%
  • Weight not given4.4%426, All reports about cats: 15%

Outcome at the time of the report

  • Recovered/Normal28.2%2,749
  • Recovered with Sequela[recovered, with a lasting effect]0.5%51
  • Ongoing32.7%3,186
  • Died3.9%380
  • Euthanized3%297
  • Outcome Unknown31.6%3,083

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 9,747 reports that give this breed.

Each share of age and weight is of the 9,747 reports that give this breed. The thin bar is the same share in the 151,153 reports about cats.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Domestic Longhair, by the year in which FDA received them
YearReports
2026470
2025977
20241,119
2023862
2022460
2021442
2020537
2019615
2018665
2017721
2016600
2015595
2014583
2013613
2012338
2011100
201015
20093
200822
20073
20064
20023

Next in the A to Z list of breeds

All reports about cats. All breeds

Cite this page

Pet Drug Reports. Domestic Longhair: adverse event reports for animal drugs. https://petdrugreports.com/breed/cat/domestic-longhair/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?

The figures are shares of the 9,747 reports about this breed received from May 2002 to June 2026. 26.8% give an age of 12 years and over. 21.1% give an age of 4 to 7 years. 2.5% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 1,026 reports in the 12 months to June 2026. It received 959 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Why are crossbred animals not in the count?

The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for cats.

Do the reports show that this breed reacts more to a drug?

No. The reports do not give the number of animals of the breed. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices