January 2024: adverse event reports received

5,784 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

5,784reports received

4,816same month a year earlier+20%

5,448monthly average, preceding 12 months

70.2%concern dogscats 17.1%

FDA's database holds 5,784 adverse event reports received in January 2024, against 4,816 in the same month a year earlier and a monthly average of 5,448 over the preceding 12 months.

70.2% of the month's reports concern dogs, 17.1% cats and 1% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were bedinvetmab (872), pyrantel pamoate + sarolaner (709) and ivermectin + pyrantel pamoate (453), and the terms listed most often were vomiting (648), lack of efficacy (endoparasite) - heartworm (512) and lethargy (462). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Bedinvetmab	872	15.1%
Pyrantel Pamoate + Sarolaner	709	12.3%
Ivermectin + Pyrantel Pamoate	453	7.8%
Fluralaner	344	5.9%
Moxidectin	327	5.7%
Gabapentin	233	4%
Afoxolaner	225	3.9%
Milbemycin Oxime + Praziquantel	222	3.8%
Frunevetmab	197	3.4%
Carprofen	159	2.7%
Oclacitinib	150	2.6%
Bexagliflozin	145	2.5%
Afoxolaner + Moxidectin + Pyrantel Pamoate	142	2.5%
Velagliflozin	129	2.2%
Maropitant	128	2.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting11.2%648
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]8.9%512
Lethargy[unusually tired or inactive]8%462
Diarrhoea[diarrhea]6.9%401
Lack of efficacy - NOS[the product did not have the expected effect]6%347
Death by euthanasia[the animal was euthanized]3.8%218
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.6%209
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]3.5%203
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]3.5%201
Death3.4%199
Seizure NOS[seizure, type not specified]3.4%198
Not eating3.3%190
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]3.2%185
Polydipsia[drinking more than usual]2.6%151
Weight loss2.6%151

Single ingredients, pooled

Pyrantel Pamoate24.2%1,398

Sarolaner15.2%881

Bedinvetmab15.1%872

Moxidectin9.8%564

Praziquantel8.8%511

Ivermectin8.6%495

Milbemycin Oxime7.4%429

Fluralaner6.6%381

Afoxolaner6.3%364

Gabapentin4%233

Frunevetmab3.4%197

Carprofen2.7%159

Species

Dog70.2%4,058

Cat17.1%989

Horse1%60

Other or not given11.7%677

Questions about January 2024

How many animal drug adverse event reports did FDA receive in January 2024?

5,784 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 4,816.

Which drugs were named most often?

By active ingredient: bedinvetmab (872), pyrantel pamoate + sarolaner (709), ivermectin + pyrantel pamoate (453), fluralaner (344) and moxidectin (327). Brands are masked in the public data.

Which signs were listed most often?

vomiting (648), lack of efficacy (endoparasite) - heartworm (512), lethargy (462), diarrhoea (401) and lack of efficacy - NOS (347).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.