January 2023: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 4,816 adverse event reports for animal drugs in January 2023. It received 3,818 reports in January 2022. The average of the 12 months before January 2023 is 4,891 reports for each month.

Of the 4,816 reports, 69.4% are about dogs, 14.8% are about cats and 1% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Jul 2021 to Jul 2023. The column with the outline is January 2023.

Reports by species

Dog69.4%3,344
Cat14.8%714
Horse1%47
Other species, or species not given14.8%711

Drug pages with reports received in January 2023

The table has every drug page with 10 or more reports that FDA received in January 2023, in order of name. No count decides which drug is in the table. The table has 91 drug pages.

Show the 91 drug pages

Drug pages with 10 or more reports received in January 2023, in order of name
Active ingredients	Reports received in January 2023
(S) - methoprene	17
Acepromazine Maleate	10
Afoxolaner	249
Alfaxalone	16
Amlodipine	11
Amoxicillin	12
Amoxicillin Trihydrate + Clavulanate Potassium	26
Atipamezole Hydrochloride	31
Betamethasone Acetate + Florfenicol + Terbinafine	10
Bupivacaine	16
Buprenorphine	148
Butorphanol Tartrate	57
Capromorelin	31
Carprofen	83
Cefovecin sodium	78
Ceftiofur Crystalline Free Acid	11
Clotrimazole + Gentamicin	14
Cyclosporine	53
Deracoxib	10
Dexamethasone	15
Dexamethasone Sodium Phosphate	10
Dexmedetomidine	48
Dexmedetomidine hydrochloride	29
Diphenhydramine	30
Doxycycline	11
Emodepside + Praziquantel	33
Enrofloxacin	22
Estriol	10
Famotidine	12
Febantel + Praziquantel + Pyrantel Pamoate	41
Firocoxib	20
Florfenicol + Mometasone furoate + Terbinafine	52
Fluoxetine hydrochloride	10
Fluralaner	263
Fluralaner + Moxidectin	30
Frunevetmab	175
Furosemide	13
Gabapentin	76
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	17
Grapiprant	46
Hydromorphone	17
Imidacloprid	30
Imidacloprid + Moxidectin	53
Insulin	59
Isoflurane	41
Ivermectin	31
Ivermectin + Pyrantel Pamoate	593
Ketamine Hydrochloride	40
Ketoconazole	10
Lotilaner	92
Lufenuron + Milbemycin Oxime	45
Lufenuron + Milbemycin Oxime + Praziquantel	58
Maropitant	116
Medetomidine hydrochloride + Vatinoxan hydrochloride	30
Melarsomine Dihydrochloride	52
Meloxicam	37
Methimazole	15
Metronidazole	13
Midazolam	26
Milbemycin Oxime	28
Milbemycin Oxime + Praziquantel	241
Milbemycin Oxime + Spinosad	117
Mirtazapine	14
Monensin	12
Moxidectin	365
Moxidectin + Pyrantel Pamoate + Sarolaner	12
Neomycin Sulfate + Nystatin + Thiostrepton + Triamcinolone Acetonide	10
Nitenpyram	64
Oclacitinib	105
Omeprazole	31
Pimobendan	73
Polysulfated Glycosaminoglycan	36
Praziquantel	27
Praziquantel + Pyrantel Pamoate	26
Prednisolone	24
Prednisone	67
Propofol	43
Pyrantel Pamoate	19
Pyrantel Pamoate + Sarolaner	744
Robenacoxib	43
Sarolaner	68
Sarolaner + Selamectin	98
Selamectin	63
Sodium Chloride	102
Spinosad	10
Tigilanol tiglate	52
Tiletamine Hydrochloride + Zolazepam Hydrochloride	13
Toceranib Phosphate	11
Trazodone	12
Trilostane	74
Verdinexor	11

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 4,816 reports of the month.

The sign that is in the largest number of the reports comes first.

Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]13.9%668 reports
Vomiting12.5%602 reports
Lethargy[unusually tired or inactive]6.9%330 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5%241 reports
Diarrhoea[diarrhea]5%239 reports
Seizure NOS[seizure, type not specified]4.3%206 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]3.9%187 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]3.5%168 reports
Death3.3%159 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.2%154 reports
Containers, Damaged[a product quality report, not a sign in an animal]2.9%142 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.8%133 reports
Behavioural disorder NOS[behaviour change, type not specified]2.5%120 reports
Not eating2.5%118 reports

Show the next 1 signs

Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]2.3%113 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in January 2023, in order of name. It has 93 ingredients.

Show the 93 ingredients

The same month in other years

Cite this page

Pet Drug Reports. January 2023: adverse event reports for animal drugs. https://petdrugreports.com/month/2023-01/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for January 2023 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Lack of efficacy (endoparasite) - heartworm" is in 668 reports of the 4,816 reports of January 2023 (13.9%).