January 2022: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 3,818 adverse event reports for animal drugs in January 2022. It received 4,565 reports in January 2021. The average of the 12 months before January 2022 is 5,263 reports for each month.

Of the 3,818 reports, 74.5% are about dogs, 10.6% are about cats and 1.2% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Jul 2020 to Jul 2022. The column with the outline is January 2022.

Reports by species

Dog74.5%2,844
Cat10.6%406
Horse1.2%44
Other species, or species not given13.7%524

Drug pages with reports received in January 2022

The table has every drug page with 10 or more reports that FDA received in January 2022, in order of name. No count decides which drug is in the table. The table has 65 drug pages.

Show the 65 drug pages

Drug pages with 10 or more reports received in January 2022, in order of name
Active ingredients	Reports received in January 2022
Afoxolaner	207
Amoxicillin Trihydrate + Clavulanate Potassium	14
Buprenorphine	16
Butorphanol Tartrate	35
Capromorelin	25
Carprofen	60
Cefovecin sodium	44
Cefpodoxime proxetil	16
Cyclosporine	35
Dexamethasone	16
Dexmedetomidine	14
Dexmedetomidine hydrochloride	21
Diphenhydramine	21
Doxycycline	25
Emodepside + Praziquantel	25
Enrofloxacin	15
Febantel + Praziquantel + Pyrantel Pamoate	42
Florfenicol + Mometasone furoate + Terbinafine	30
Fluralaner	258
Fluralaner + Moxidectin	35
Furosemide	10
Gabapentin	37
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	16
Grapiprant	43
Hydromorphone	11
Imidacloprid	54
Imidacloprid + Moxidectin	50
Insulin	56
Isoflurane	17
Ivermectin	37
Ivermectin + Praziquantel + Pyrantel Pamoate	10
Ivermectin + Pyrantel Pamoate	530
Ketamine Hydrochloride	15
Lotilaner	61
Lufenuron + Milbemycin Oxime	50
Lufenuron + Milbemycin Oxime + Praziquantel	57
Maropitant	67
Melarsomine Dihydrochloride	68
Meloxicam	26
Metronidazole	10
Milbemycin Oxime	36
Milbemycin Oxime + Praziquantel	242
Milbemycin Oxime + Spinosad	141
Mirtazapine	10
Monensin	12
Moxidectin	305
Nitenpyram	68
Oclacitinib	89
Omeprazole	14
Pimobendan	28
Polysulfated Glycosaminoglycan	38
Praziquantel	19
Praziquantel + Pyrantel Pamoate	23
Prednisolone	15
Prednisone	40
Pyrantel Pamoate	20
Pyrantel Pamoate + Sarolaner	484
Robenacoxib	21
Sarolaner	73
Sarolaner + Selamectin	84
Selamectin	63
Sodium Chloride	58
Spinosad	23
Tigilanol tiglate	36
Trilostane	71

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 3,818 reports of the month.

The sign that is in the largest number of the reports comes first.

Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]15.1%576 reports
Vomiting14.6%557 reports
Lethargy[unusually tired or inactive]8%307 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.7%219 reports
Diarrhoea[diarrhea]5.5%210 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]4.8%183 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]4.2%160 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]4.1%157 reports
Seizure NOS[seizure, type not specified]3.7%142 reports
Death3%113 reports
Emesis (multiple)[vomiting more than once]2.7%103 reports
Containers, Damaged[a product quality report, not a sign in an animal]2.6%99 reports
Not eating2.6%99 reports
Underdose[less than the labelled amount was given]2.3%88 reports

Show the next 1 signs

Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]2.3%87 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in January 2022, in order of name. It has 66 ingredients.

Show the 66 ingredients

The same month in other years

Cite this page

Pet Drug Reports. January 2022: adverse event reports for animal drugs. https://petdrugreports.com/month/2022-01/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for January 2022 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Lack of efficacy (endoparasite) - heartworm" is in 576 reports of the 3,818 reports of January 2022 (15.1%).