January 2003: adverse event reports received

1,058 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,058reports received

1,170same month a year earlier-10%

1,102monthly average, preceding 12 months

55.6%concern dogscats 9.8%

FDA's database holds 1,058 adverse event reports received in January 2003, against 1,170 in the same month a year earlier and a monthly average of 1,102 over the preceding 12 months.

55.6% of the month's reports concern dogs, 9.8% cats and 2.2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were moxidectin (322), selamectin (204) and carprofen (79), and the terms listed most often were vomiting (166), vials, Leaking (130) and ineffective, heartworm larvae (110). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Moxidectin	322	30.4%
Selamectin	204	19.3%
Carprofen	79	7.5%
Deracoxib	64	6%
Tilmicosin Phosphate	33	3.1%
Etodolac	28	2.6%
Ivermectin	25	2.4%
Melarsomine Dihydrochloride	23	2.2%
Ivermectin + Pyrantel Pamoate	21	2%
Milbemycin Oxime	17	1.6%
Tiletamine Hydrochloride + Zolazepam Hydrochloride	17	1.6%
Amoxicillin	16	1.5%
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	13	1.2%
Enrofloxacin	13	1.2%
Ketamine Hydrochloride	13	1.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting15.7%166
Vials, Leaking[a product quality report, not a sign in an animal]12.3%130
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]10.4%110
Depression[dull, quiet or withdrawn]10.3%109
Death10%106
Anorexia[not eating]8.5%90
Anaphylaxis[sudden severe allergic-type reaction]6%63
Accidental exposure[exposure that was not intended]5.6%59
Diarrhoea[diarrhea]5.4%57
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.4%47
Ataxia[unsteady, uncoordinated movement]3.4%36
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]3.3%35
Convulsion[seizure]3.2%34
Death by euthanasia[the animal was euthanized]3.2%34
Unclassifiable adverse event[event that fits no dictionary term]3.2%34

Single ingredients, pooled

Moxidectin30.4%322

Selamectin19.3%204

Carprofen7.5%79

Deracoxib6%64

Ivermectin4.8%51

Tilmicosin Phosphate3.1%33

Etodolac2.6%28

Melarsomine Dihydrochloride2.2%23

Pyrantel Pamoate2.2%23

Milbemycin Oxime1.7%18

Tiletamine Hydrochloride1.6%17

Zolazepam Hydrochloride1.6%17

Species

Dog55.6%588

Cat9.8%104

Horse2.2%23

Other or not given32.4%343

Questions about January 2003

How many animal drug adverse event reports did FDA receive in January 2003?

1,058 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,170.

Which drugs were named most often?

By active ingredient: moxidectin (322), selamectin (204), carprofen (79), deracoxib (64) and tilmicosin phosphate (33). Brands are masked in the public data.

Which signs were listed most often?

vomiting (166), vials, Leaking (130), ineffective, heartworm larvae (110), depression (109) and death (106).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.