December 2020: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 4,308 adverse event reports for animal drugs in December 2020. It received 4,220 reports in December 2019. The average of the 12 months before December 2020 is 5,690 reports for each month.

Of the 4,308 reports, 72.8% are about dogs, 9.9% are about cats and 1.3% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Jun 2019 to Jun 2021. The column with the outline is December 2020.

Reports by species

Dog72.8%3,136
Cat9.9%426
Horse1.3%58
Other species, or species not given16%688

Drug pages with reports received in December 2020

The table has every drug page with 10 or more reports that FDA received in December 2020, in order of name. No count decides which drug is in the table. The table has 71 drug pages.

Show the 71 drug pages

Drug pages with 10 or more reports received in December 2020, in order of name
Active ingredients	Reports received in December 2020
Acepromazine Maleate	10
Afoxolaner	231
Amoxicillin Trihydrate + Clavulanate Potassium	19
Betamethasone Acetate + Florfenicol + Terbinafine	15
Buprenorphine	21
Butorphanol Tartrate	29
Capromorelin	15
Carprofen	68
Cefovecin sodium	51
Cefpodoxime proxetil	15
Ceftiofur Crystalline Free Acid	19
Clotrimazole + Gentamicin	17
Cyclosporine	31
Dexamethasone	22
Dexmedetomidine	10
Dexmedetomidine hydrochloride	14
Diphenhydramine	36
Doxycycline	26
Emodepside + Praziquantel	29
Enrofloxacin	21
Eprinomectin	13
Febantel + Praziquantel + Pyrantel Pamoate	48
Fenbendazole	16
Firocoxib	13
Florfenicol + Mometasone furoate + Terbinafine	42
Fluralaner	329
Fluralaner + Moxidectin	30
Gabapentin	39
Grapiprant	60
Imidacloprid	50
Imidacloprid + Moxidectin	64
Insulin	63
Isoflurane	24
Ivermectin	53
Ivermectin + Praziquantel + Pyrantel Pamoate	12
Ivermectin + Pyrantel Pamoate	623
Ketamine Hydrochloride	35
Lotilaner	98
Lufenuron + Milbemycin Oxime	90
Lufenuron + Milbemycin Oxime + Praziquantel	60
Maropitant	65
Melarsomine Dihydrochloride	75
Meloxicam	38
Midazolam	11
Milbemycin Oxime	31
Milbemycin Oxime + Praziquantel	309
Milbemycin Oxime + Spinosad	252
Monensin	15
Moxidectin	342
Nitenpyram	70
Oclacitinib	124
Omeprazole	25
Orbifloxacin	12
Phenylpropanolamine hydrochloride	10
Pimobendan	24
Polysulfated Glycosaminoglycan	27
Praziquantel	16
Praziquantel + Pyrantel Pamoate	20
Prednisolone	16
Prednisone	46
Propofol	16
Pyrantel Pamoate	28
Pyrantel Pamoate + Sarolaner	294
Robenacoxib	15
Sarolaner	117
Sarolaner + Selamectin	96
Selamectin	75
Sodium Chloride	56
Spinosad	44
Trilostane	77
Tulathromycin	14

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 4,308 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting16%688 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]13.2%567 reports
Lethargy[unusually tired or inactive]8.5%365 reports
Diarrhoea[diarrhea]5.3%228 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]4.4%189 reports
Lack of efficacy - NOS[the product did not have the expected effect]3.8%163 reports
Seizure NOS[seizure, type not specified]3.7%159 reports
Death3.3%142 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]3.1%134 reports
Not eating2.4%103 reports
Behavioural disorder NOS[behaviour change, type not specified]2.3%99 reports
Emesis (multiple)[vomiting more than once]2.3%97 reports
Anorexia[not eating]2.2%96 reports
Lack of efficacy (endoparasite) - NOS[the product did not have the expected effect: target not specified]2.2%95 reports

Show the next 1 signs

Unpalatable[legacy FDA term: the animal would not take it]2.2%94 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in December 2020, in order of name. It has 67 ingredients.

Show the 67 ingredients

The same month in other years

Cite this page

Pet Drug Reports. December 2020: adverse event reports for animal drugs. https://petdrugreports.com/month/2020-12/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for December 2020 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 688 reports of the 4,308 reports of December 2020 (16%).