December 2002: adverse event reports received

807 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

807reports received

900same month a year earlier-10%

1,110monthly average, preceding 12 months

61.5%concern dogscats 10%

FDA's database holds 807 adverse event reports received in December 2002, against 900 in the same month a year earlier and a monthly average of 1,110 over the preceding 12 months.

61.5% of the month's reports concern dogs, 10% cats and 2.6% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (164), moxidectin (156) and carprofen (62), and the terms listed most often were vomiting (125), depression (119) and anorexia (99). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	164	20.3%
Moxidectin	156	19.3%
Carprofen	62	7.7%
Deracoxib	44	5.5%
Enrofloxacin	28	3.5%
Tilmicosin Phosphate	26	3.2%
Amoxicillin	21	2.6%
Monensin	21	2.6%
Etodolac	18	2.2%
Ivermectin + Pyrantel Pamoate	18	2.2%
Ketamine Hydrochloride	17	2.1%
Melarsomine Dihydrochloride	17	2.1%
Ivermectin	16	2%
Milbemycin Oxime	15	1.9%
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	9	1.1%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting15.5%125
Depression[dull, quiet or withdrawn]14.7%119
Anorexia[not eating]12.3%99
Death10.7%86
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]9.7%78
Anaphylaxis[sudden severe allergic-type reaction]7.8%63
Accidental exposure[exposure that was not intended]7.4%60
Diarrhoea[diarrhea]5.6%45
Unclassifiable adverse event[event that fits no dictionary term]5%40
Fever4.7%38
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.6%37
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]4.5%36
Death by euthanasia[the animal was euthanized]4.3%35
Urticaria[hives]4.2%34
Convulsion[seizure]4.1%33

Single ingredients, pooled

Selamectin20.3%164

Moxidectin19.3%156

Carprofen7.7%62

Deracoxib5.5%44

Ivermectin4.3%35

Enrofloxacin3.5%28

Tilmicosin Phosphate3.2%26

Pyrantel Pamoate2.9%23

Monensin2.7%22

Amoxicillin2.6%21

Milbemycin Oxime2.6%21

Etodolac2.2%18

Species

Dog61.5%496

Cat10%81

Horse2.6%21

Other or not given25.9%209

Questions about December 2002

How many animal drug adverse event reports did FDA receive in December 2002?

807 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 900.

Which drugs were named most often?

By active ingredient: selamectin (164), moxidectin (156), carprofen (62), deracoxib (44) and enrofloxacin (28). Brands are masked in the public data.

Which signs were listed most often?

vomiting (125), depression (119), anorexia (99), death (86) and ineffective, heartworm larvae (78).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.